Alzheimer’s-like symptoms reversed in animal study

Alzheimer’s-like symptoms reversed in animal study

Alzheimer’s-like symptoms reversed in animal study

For this study, the researchers took a look at two compounds: EGCG, or epigallocatechin-3-gallate, a key ingredient in green tea, and FA, or ferulic acid, which is found in carrots, tomatoes, rice, wheat and oats.

“After three months, combination treatment completely restored working memory and the Alzheimer’s mice performed just as well as the healthy comparison mice,” Town said.

Takashi Mori, Naoki Koyama, Jun Tan, Tatsuya Segawa, Masahiro Maeda, Terrence Town. Combined treatment with the phenolics (−)-epigallocatechin-3-gallate and ferulic acid improves cognition and reduces Alzheimer-like pathology in mice. Journal of Biological Chemistry, 2019; 294 (8): 2714 DOI: 10.1074/jbc.RA118.004280

Alzheimer disease, flavonoid, amyloid precursor protein (APP), amyloid-beta (AB), secretase, transgenic, neuroinflammation, oxidative stress, nonamyloidogenic, phenol, plant polyphenol, egcg, ferulic acid, green tea

Author: Ralph Turchiano

In short, I review clinical research on an almost daily basis. What I post tends to be articles that are relevant to the readers in addition to some curiosities that have intriguing potential. As a hobby, I truly enjoy the puzzle-solving play that statistics and programming as in the python language bring to the table. I just do not enjoy problem-solving, I love problem-solving and the childlike inspiration and exploration of that innocent exhilaration of discovering something new. Enjoy ;-)