COVID Vaccines not being tested to work, CBD a COVID Lung Saver?, Shoes thee COVID carrier and Data.

This week we review disturbing vaccine study requirements, CBD an incredible gem if possibly protecting the lungs and restoring oxygen levels, and a strong correlation as to shoes being an unrecognized major disease vector. In addition to looking at COVID data correlations to which countries are locking down in response Sars-COV-2 to those which have not or have done little. #covidvaccine #covidvector #covidnews Data Sources API for DataFrames: The COVID Tracking Project Our wold in Data (Oxford) Links: https://www.eurekalert.org/pub_releases/2020-10/uoo-ecw102220.php#.X5N_7_DuPM0.wordpress https://www.eurekalert.org/pub_releases/2020-10/b-cvt102020.php#.X5OGbCHAYR8.wordpress https://www.eurekalert.org/pub_releases/2020-10/mcog-chr101620.php#.X45lOsCeu4k.wordpress https://wwwnc.cdc.gov/eid/article/26/7/20-0885_article

COVID19 Analytics – Mask Trash and Shoes a Major Spreader, Newsom & Fauci Being Odd, Florida Wins

Our weekly review of the current COVID data and country comparisons as well as other oddities such as Mask Litter, Trash Cans, and Shoes being unintended spreaders. All this under the guise of Amateur Python Analytics. Brief CSV File Request Code below (Pandas). That will allow you to pull Oxford University Data up to the current date. Enjoy 😉

This is a long one, next week I will make it A LOT shorter.

#covid19 #sarscov2 #data

Code Snippet:
import pandas as pd
import csv
import requests
younameit = pd.read_csv(‘https://covid.ourworldindata.org/data/owid-covid-data.csv’)

https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/bulletins/deathsduetocoronaviruscovid19comparedwithdeathsfrominfluenzaandpneumoniaenglandandwales/deathsoccurringbetween1januaryand31august2020

https://wwwnc.cdc.gov/eid/article/26/7/20-0885_article

https://www.eurekalert.org/pub_releases/2020-10/uoh-rci100120.php#.X3fUGZsAGM0.wordpress

https://www.cidrap.umn.edu/news-perspective/2020/04/commentary-masks-all-covid-19-not-based-sound-data

Vitamin D may be more effective than masks and distancing combined for COVID ?

Vitamin D may be more effective than masks and distancing combined for COVID ?

In patients older than 40 years they observed that those patients who were vitamin D sufficient were 51.5 percent less likely to die from the infection compared to patients who were vitamin D deficient or insufficient with a blood level of 25-hydroxyvitamin D less than 30 ng/mL.

Holick, who most recently published a study which found that a sufficient amount of vitamin D can reduce the risk of catching coronavirus by 54 percent, believes that being vitamin D sufficient helps to fight consequences from being infected not only with the corona virus but also other viruses causing upper respiratory tract illnesses including influenza. “There is great concern that the combination of an influenza infection and a coronal viral infection could substantially increase hospitalizations and death due to complications from these viral infections.”

#covid19 #sarscov2 #vitaminD

Kaufman HW, Niles JK, Kroll MH, Bi C, Holick MF (2020) SARS-CoV-2 positivity rates associated with circulating 25-hydroxyvitamin D levels. PLOS ONE 15(9): e0239252. https://doi.org/10.1371/journal.pone.0239252

Pandemic Charting – Weaponizing Uncertainty – Countries Do better with a Light touch – Python Data

COVID-19 Made worse By Social Distancing?

We are led to question whether the recommended social distancing measures to prevent SARS-CoV-2 transmission could increase the number of other serious instabilities. The breaking of the contagion pathways reduces the sharing of microorganisms between people, thus favoring dysbiosis, which, in turn, may increase the poor prognosis of the disease. #covid #microbiome #dysbiosis Célia P. F. Domingues, João S. Rebelo, Francisco Dionisio, Ana Botelho, Teresa Nogueira. The Social Distancing Imposed To Contain COVID-19 Can Affect Our Microbiome: a Double-Edged Sword in Human Health. mSphere, 2020; 5 (5) DOI: 10.1128/mSphere.00716-20 https://msphere.asm.org/content/5/5/e00716-20

Lockdowns a Complete Failure compared to controls – Countries that did not? Python Analysis Part 2

Part 2 as promised. We compare cases and death per million from industrialized countries which did little to nothing to Great Britain and the United States. The Data extrapolated is from: https://ourworldindata.org/coronaviru…
#covid19 #lockdown #socialdistancing

(Volume is kind of Choppy midpoint)
Additional Code: From Part 1:
datasw = data.loc[data.iso_code==’SWE’, :]
datagb = data.loc[data.iso_code==’GBR’, :]
dataus = data.loc[data.iso_code==’USA’, :]
datasg = data.loc[data.iso_code==’SGP’, :]
datajp = data.loc[data.iso_code==’JPN’, :]
datako = data.loc[data.iso_code==’KOR’, :]
datatw = data.loc[data.iso_code==’TWN’, :]
dataall = [datagb,dataus,datasw,datasg,datajp,datako, datatw]
dataall = pd.concat(dataall)
dataall
dataall.datetime = pd.to_datetime(dataall.date)
dataall.set_index(‘date’, inplace=True)
fig, ax = plt.subplots(figsize=(50,25))
dataall.groupby(‘iso_code’)[‘new_cases_smoothed_per_million’].plot(legend=True,fontsize = 20, linewidth=7.0)
ax.legend([‘Great Britain = Lockdown’,’Japan = No LD’, ‘South Korea = No LD’, ‘Singapore = LD JUNE -Migrant LD HIghest POP Density’, ‘Sweden = No LD’, ‘Taiwan = No LD’,’USA = Lockdown’],prop=dict(size=50))
comp = dataall.loc[‘2020-09-18’]
comp.set_index(“iso_code”, inplace=True)
comp= pd.DataFrame(comp[[‘total_cases_per_million’,’total_deaths_per_million’]])
plt.rc(‘legend’, fontsize=50)
comp.plot.bar(rot=0, figsize=(20,20),fontsize=30)

Pandemic Over? COVID-19 World data Amateur Python Analysis

From an educational perspective, we review current COVID-19 data and arrive look at lockdowns and population density appears to have no numerical effect currently on COVID-19. In any case, this is more about exploring the code from a beginner’s standpoint with Python and DataFrames.
#covid19 #pandemicover #coviddata
CSV files found here:
https://ourworldindata.org/coronaviru…
Code: (Had to remove the angle brackets)
import numpy as np
import pandas as pd
from scipy import stats
import statsmodels.api as sm
import matplotlib.pyplot as plt
import pandas as pd
from scipy.stats import spearmanr
from scipy.stats import kendalltau
from scipy.stats import pearsonr
from scipy import stats
import seaborn as sns
import warnings
warnings.filterwarnings(“ignore”)
#Pandemic
Claim Currently Invalid —Ralph Turchiano
data = pd.read_csv(‘owid-covid-data-19SEP2020.csv’)
data.info()
pd.set_option(‘max_columns’, None)
data.tail(5)
data[‘date’] = pd.to_datetime(data[‘date’])
data.info()
data_18SEP = data[data[‘date’]==’2020-09-18′]
data_ind = data_18SEP[data_18SEP[‘human_development_index’]=.8]
data_ind.head(10)
data_ind.drop([‘iso_code’,’continent’,’handwashing_facilities’,’stringency_index’,], axis=1, inplace=True)
data_ind.columns
data_ind[‘extreme_poverty’].fillna(0, inplace=True)
data_compare = pd.DataFrame([data.loc[37991],data.loc[41736]])
data_compare
data_compare.set_index(‘location’,inplace=True)
data_compare[‘total_cases_per_million’]
data_Swe_USA=pd.DataFrame(data_compare[[‘total_cases_per_million’,’new_cases_per_million’,’new_deaths_per_million’]])
data_Swe_USApd.DataFrame(data_compare[[‘total_cases_per_million’,’new_cases_per_million’,’new_deaths_per_million’]])
data_Swe_USA
data_ind.drop([‘date’,’new_cases’,’new_deaths’,’total_tests’, ‘total_tests_per_thousand’,
‘new_tests_per_thousand’, ‘new_tests_smoothed’, ‘new_tests’,
‘new_tests_smoothed_per_thousand’, ‘tests_per_case’,’tests_units’,’new_deaths_per_million’,’positive_rate’ ], axis=1, inplace=True)
data_ind.tail()
data_ind.dropna(inplace=True)
data_ind.corr(“kendall”)
data_18SEP.tail()
data_18SEP.loc[44310]
data_18SEP.loc[44310,[‘new_cases_smoothed_per_million’,’new_deaths_smoothed_per_million’]]
New =pd.DataFrame(data[[‘new_cases_smoothed_per_million’,’new_deaths_smoothed_per_million’]])
New.corr(‘kendall’)
dataw = data.loc[data[‘iso_code’] == ‘OWID_WRL’]
dataw
dataw.datetime = pd.to_datetime(data.date)
dataw.set_index(‘date’, inplace=True)
data_cl = pd.DataFrame(dataw[[‘new_deaths_smoothed’,’new_cases_smoothed’]])
data_cl.dropna(inplace=True)
data_cl.plot(figsize=(30,12))
data_cl.tail(20)

COVID-19 Tracking Data API and Data Anomalies (No Correlations? Cases to Hospitalizations Increases)

Is there a correlation between Positive cases and Hospitalizations? Below is the API for python access, open to all who desire to filter the data. I want to just give easy access to all the beginner students data scientists out there, such as myself..Explore and Discover: **My Apologies It says High Def, but does not look High Def on video here**

Code: import matplotlib.pyplot as plt import pandas as pd from scipy import stats import statsmodels.api as sm import requests import time from IPython.display import clear_output response = requests.get(“https://covidtracking.com/api/v1/us/daily.csv”) covid = response.content ccc = open(“daily.csv”,”wb”) ccc.write(covid) ccc.close() df = pd.read_csv(“daily.csv”, index_col = ‘date’) df.head() data = df[[‘positiveIncrease’,’hospitalizedIncrease’]] dataT = df[[‘positiveIncrease’,’hospitalizedIncrease’,’hospitalizedCurrently’]] dataD = df[[‘hospitalizedIncrease’,’deathIncrease’]] dataT.head(20) plt.figure(figsize=(20,10)) Y = data[‘positiveIncrease’] X = data[‘hospitalizedIncrease’] plt.scatter(X,Y) plt.ylabel(“Tested Positive Increase”) plt.xlabel(“Hospitalization Increase”) plt.show() Y1 = sm.add_constant(Y) reg = sm.OLS(X, Y1).fit() reg.summary() data.plot(y=[‘hospitalizedIncrease’,’positiveIncrease’],xticks=data.index[0:len(data):30], rot=90, figsize=(20,10) ) for x in range(len(data)): plt.figure(figsize=(20,10)) plt.xticks( data.index.values[0:len(data):30], rotation = 90, fontsize=20 ) plt.plot(data.tail(x))

Honeysuckle Decoction Inhibits SARS-CoV-2

In a new study in Cell Discovery, Chen-Yu Zhang’s group at Nanjing University and two other groups from Wuhan Institute of Virology and the Second Hospital of Nanjing present a novel finding that absorbed miRNA MIR2911 in honeysuckle decoction (HD) can directly target SARS-CoV-2 genes and inhibit viral replication. Drinking of HD accelerate the negative conversion of COVID-19 patients.

#mir2911 #sarcov2 #honeysuckle

Zhou, L., Zhou, Z., Jiang, X. et al. Absorbed plant MIR2911 in honeysuckle decoction inhibits SARS-CoV-2 replication and accelerates the negative conversion of infected patients. Cell Discov 6, 54 (2020). https://doi.org/10.1038/s41421-020-00197-3

https://www.nature.com/articles/s41421-020-00197-3#ethics

An easier way to go vegan, Vitamin B12 CAN be produced during grain fermentation

The highest production was found in the rice bran (ca. 742 ng/g dw), followed by the buckwheat bran (ca. 631 ng/g dw), after fermentation. Meanwhile, the addition of L. brevis was able to dominate indigenous microbes during fermentation and thus greatly improve microbial safety during the fermentation of different grain materials. #b12 #vegan #fermentation https://helda.helsinki.fi/bitstream/handle/10138/317682/insitufo.pdf?sequence=1&isAllowed=y In situ fortification of vitamin B12 in grain materials by fermentation withPropionibacterium freudenreichii, Chong Xie ISBN 978-951-51-6355-4 (PAPERBACK) ISBN 978-951-51-6356-1 (PDF, http://ETHESIS.HELSINKI.FI) ISSN 0355-1180 UNIGRAFIA HELSINKI 2020

More COVID Research Information Censored

More COVID Research Censored CDC and the WHO, to my dismay, are either directly or indirectly controlling the flow of information and research, possibly creating an echo chamber of bias. The level of censorship is getting so out of control; it is highly likely now it may be resulting in harm in a variety of societal dimensions. As well as the Freedom to Speech is becoming rapidly stratified among those in positions of wealth, power, or fame, It is becoming painfully apparent that self-proclaimed thought leaders may not be behooving us in times of crisis, manufactured, self-inflicted, or real. At the very least, by not reviewing and growing from our errors, we are, in all essence, committed to repeating them. Freedom of Speech, in its most basic form, is simply the freedom to speak. Take that right away from one, and you build a case to take it away from all, for, of course, your own protection. #censorship #freedomofspeech #covid

Was the Stock Market brought down by a cyberattack ?

Editors Note: There are many rumors flying around currently at the unusual coincidences that occurred prior to the shut down. While I am not going to add directly to the speculation such as the photo present by the IBT.  I will give you an idea of the current cybe rwar being conducted with the help of Norse. Even though a little over dramatic, it is like watching someone else play a video game. It is good to get an idea of the daily routine, especially in a world where many do not know what a DDOS attack really is. Enjoy ;-)- Ralph Turchiano

stock

Enlarge the Videos and watch in HD

A little closer

Invasive Candida reversed by Common Herb (In Vitro)


Invasive Candida reversed by Common Herb (In Vitro)

C. albicans cells exist in different morphological states (yeast, pseudohypha, hypha) and can undergo white-opaque phenotype switching in certain conditions. The ability to convert from yeast or pseudohyphal states to the hyphal growth state is critical for systemic infection

The Candida albicans fungus also makes a biofilm, which is a fungal cell collection that can be difficult to treat. The researchers found that the gymnemic acid compounds converted the biofilm back to treatable yeast cells.

“This compound prevents the biofilm formation because hyphae are the major builders of biofilms and biofilms are resistant to antifungals,” Vediyappan said. “Yeast cells by themselves cannot make biofilms and are sensitive to antifungal treatments.”

The gymnemic acid compounds are nontoxic, which is especially important for cancer patients and other immunocompromised patients. The gymnemic acids can stop the unwanted invasive infection while preserving important healthy cells.

Please like us on http://www.facebook.com/vitaminandherbstore to stay current or http://www.youtube.com/vhfilm for our archive.

Gymnemic Acids Inhibit Hyphal Growth and Virulence in Candida albicans Published: September 11, 2013 DOI:
10.1371/journal.pone.0074189

Research treats the fungus among us with nontoxic medicinal compound

Vitamin Wars – Will keep posted till the end of February 2014

EEV: Video posted here at request – That’s me So Don’t Troll me Bro 😉

Brief Commentary in regards to the Dr. OZ show and his upcoming guest. Discusses the plea that we need to stop relying on those who do not present facts to back up their outrageous claims. In addition to recognize, that we the public are being ignored by all sides in a quest for unbiased knowledge.

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165th Health Research Report 5 OCT 2015 ( Synopsis)

ScreenHunter_42 Dec. 31 12.07           

Health Research Report

165th Issue Date 5 OCT 2013

Compiled By Ralph Turchiano

FOUND AT :

 

www.healthresearchreport.me 

In This Issue:

1.    Melatonin helps control weight gain as it stimulates the appearance of ‘beige fat’

2.    Folic acid deficiency can affect the health of great, great grandchildren

3.    Mouse studies reveal promising vitamin D-based treatment for MS

4.    Organized screening for prostate cancer does more harm than good

5.    Niacin, the fountain of youth

6.    Red wine chemical remains effective against cancer after the body converts it

7.    Component of citrus fruits found to block the formation of kidney cysts

163rd Health Research Report Synopsis 07 SEP 2013

 

Health Research Report

163rd Issue Date 7 SEP 2013

Compiled By Ralph Turchiano

www.healthresearchreport.me 

In this issue:

  1. Four or more cups of coffee a day may keep prostate cancer recurrence and progression away
  2. Broccoli could be key in the fight against osteoarthritis
  3. Potential diagnostic marker for zinc status offers insights into the effects of zinc deficiency
  4. Doubling the daily allowance of protein intake with diet and exercise protects muscle loss
  5. Oral nutritional supplements demonstrate significant health and cost benefits
  6. 1 in 4 has alarmingly few intestinal bacteria
  7. Aging really is ‘in your head’
  8. Exercise may reduce the risk of epilepsy later in life for men
  9. Antioxidant effect of resveratrol in the treatment of vascular dementia

161st Health Research Report 10 AUG 2013 – Synopsis

www.healthresearchreport.me 

 

 

In this issue:

1.       Plant-Based Compound May Inhibit HIV Infection, Research Shows

2.       Methamphetamine increases susceptibility to deadly fungal infection

3.       Exercise May be the Best Medicine for Alzheimer’s

4.       Study finds evidence of nerve damage in around half of fibromyalgia patients

5.       Blocking sugar intake may reduce cancer risk or progression in obese and diabetic people

6.       Fatty acids could aid cancer prevention and treatment

7.       Illinois scientists put cancer-fighting power back into frozen broccoli

8.       Diets of Pregnant Women Contain Harmful, Hidden Toxins

9.       L-3-n-butylphthalide protects against cognitive dysfunction in vascular dementia

 ScreenHunter_42 Dec. 31 12.07

Health Research Report

161st Issue Date 10 AUG 2013

Compiled By Ralph Turchiano

www.vit.bz

www.youtube.com/vhfilm

 www.facebook.com/engineeringevil

Topics of the 160th Health Research Report 26 JUL 2013

ScreenHunter_42 Dec. 31 12.07

Health Research Report

160th Issue Date 26 JUL 2013

Compiled By Ralph Turchiano

www.healthresearchreport.me 

 

1. Prostate cancers are fewer, smaller on walnut-enriched diet

2. What are Fructooliogosaccharides and How Do They Provide Digestive, Immunity and Bone Health Benefits?

3. Vitamins and minerals can boost energy and enhance mood

4. Uncovering a healthier remedy for chronic pain

5. Breastfeeding Could Prevent ADHD

6. A ginkgo biloba extract promotes proliferation of endogenous neural stem cells

7. Bad sleep around full moon is no longer a myth

 

151st Health Research Report 22 MAR 2013

In this Issue:

Folic acid lowers risk of autism

Bitter melon juice prevents pancreatic cancer in mouse models

Study: Probiotics reduce stress-induced intestinal flare-ups

Green tea, coffee may help lower stroke risk

How oils and fats regulate feeling of satiety

Study Shows How Vitamin E Can Help Prevent Cancer

New study highlights strong anti-cancer properties of soybeans

Explaining how extra virgin olive oil protects against Alzheimer’s disease

Vectorproof[1]

Health Research Report

151st Issue Date 22 Mar 2013

Compiled By Ralph Turchiano

www.vit.bz

www.youtube.com/vhfilm

 www.facebook.com/engineeringevil

www.healthresearchreport.me 

120922_0002

91st Health Research Report 10 OCT 2010 – Reconstruction

store logo

Health Research Report

91st Issue 10 OCT 2010

Compiled By Ralph Turchiano

www.vit.bz

www.youtube.com/vhfilm 

www.facebook.com/engineeringevil

www.engineeringevil.com  

www.healthresearchreport.me 

120922_0002

 

Editors Top Five:

 

1. Diabetes risk may fall as magnesium intake climbs

2. J&J, FDA leaders take heat for ‘phantom’ recall

3. Vitamin D deficiency rampant in patients undergoing orthopedic surgery, damaging patient recovery

4. Think saturated fat contributes to heart disease? Think again

5. Surprise: Scientists discover that inflammation helps to heal wounds

 

In this Issue:

 

1. Diabetes risk may fall as magnesium intake climbs

2. UM School of Medicine Center for Celiac Research finds rate of celiac disease is growing

3. Sparkling drinks spark pain circuits

4. Maternal diet high in trans fats doubles risk of excess body fat in breastfed babies, study finds

5. Garlic oil shows protective effect against heart disease in diabetes

6. Blueberries help fight artery hardening, lab animal study indicates

7. IU researchers: Chemotherapy alters brain tissue in breast cancer patients

8. Dirty hands, dirty mouths: U-M study finds a need to clean the body part that lies

9. Research examines vicious cycle of overeating and obesity

10. Dog ownership is associated with reduced eczema in children with dog allergies

11. Faith in God associated with improved survival after liver transplantation

12. Drugs for low libido raise concerns over industry ‘construction’ of new diseases

13. Bioethics scholars fault requirement that all women in clinical drug trials use contraception

14. J&J, FDA leaders take heat for ‘phantom’ recall

15. Vitamin D levels lower in African-Americans

16. Vigorous exercise reduces breast cancer risk in African-American women

17. Think saturated fat contributes to heart disease? Think again

18. Sleep loss limits fat loss

19. Walnuts, walnut oil, improve reaction to stress

20. Surprise: Scientists discover that inflammation helps to heal wounds

21. Amino acid supplement makes mice live longer

22. Shortfalls in carotenoid ( Pro-Vitamin A )intake may impact women’s health

23. Low Testosterone Linked to Alzheimer’s Disease

24. Vitamin D deficiency rampant in patients undergoing orthopedic surgery, damaging patient recovery

 

Public release date: 24-Sep-2010

 

Diabetes risk may fall as magnesium intake climbs

 

NEW YORK (Reuters Health) – Getting enough magnesium in your diet could help prevent diabetes, a new study suggests.

 

People who consumed the most magnesium in foods and from vitamin supplements were about half as likely to develop diabetes over the next 20 years as people who took in the least magnesium, Dr. Ka He of the University of North Carolina at Chapel Hill and colleagues found.

 

The results may explain in part why consuming whole grains, which are high in magnesium, is also associated with lower diabetes risk. However, large clinical trials testing the effects of magnesium on diabetes risk are needed to determine whether a causal relationship truly exists, the researchers note in Diabetes Care.

 

It’s plausible that magnesium could influence diabetes risk because the mineral is needed for the proper functioning of several enzymes that help the body process glucose, the researchers point out. Studies of magnesium and diabetes risk have had conflicting results, though.

 

To investigate the link, the researchers looked at magnesium intake and diabetes risk in 4,497 men and women 18 to 30 years old, none of whom were diabetic at the study’s outset. During a 20-year follow-up period, 330 of the subjects developed diabetes.

 

People with the highest magnesium intake, who averaged about 200 milligrams of magnesium for every 1,000 calories they consumed, were 47 percent less likely to have developed diabetes during follow up than those with the lowest intakes, who consumed about 100 milligrams of magnesium per 1,000 calories.

 

He and colleagues also found that as magnesium intake rose, levels of several markers of inflammation decreased, as did resistance to the effects of the key blood-sugar-regulating hormone insulin. Higher blood levels of magnesium also were linked to a lower degree of insulin resistance.

 

“Increasing magnesium intake may be important for improving insulin sensitivity, reducing systemic inflammation, and decreasing diabetes risk,” He and colleagues write. “Further large-scale clinical trials are needed to establish causal inference and elucidate the mechanisms behind this potential benefit.”

 

SOURCE: http://link.reuters.com/xuz35p Diabetes Care, published online August 31, 2010.

 

Public release date: 27-Sep-2010

 

UM School of Medicine Center for Celiac Research finds rate of celiac disease is growing

 

Study finds increasing number of celiac cases, particularly in the elderly

Working to solve the puzzle of when people develop celiac disease has led researchers from the University of Maryland School of Medicine Center for Celiac Research to some surprising findings. They have found that the autoimmune disorder is on the rise with evidence of increasing cases in the elderly. An epidemiological study published September 27 in the Annals of Medicine supports both trends—with interesting implications for possible treatment and prevention.

 

“You’re never too old to develop celiac disease,” says Alessio Fasano, M.D., director of the University of Maryland’s Mucosal Biology Research Center and the celiac research center, which led the study. The Universita Politecnica delle Marche in Ancona, Italy; the Johns Hopkins Bloomberg School of Public Health; the Women & Children’s Hospital of Buffalo; and Quest Diagnostics Inc. of San Juan Capistrano, Calif., also participated.

 

Celiac disease is triggered by consuming gluten, a protein found in wheat, barley and rye. Classic symptoms include diarrhea, intestinal bloating and stomach cramps. Left untreated, it can lead to the malabsorption of nutrients, damage to the small intestine and other medical complications.

 

Since 1974, in the U.S., the incidence of the disorder has doubled every 15 years. Using blood samples from more than 3,500 adults, the researchers found that the number of people with blood markers for celiac disease increased steadily from one in 501 in 1974 to one in 219 in 1989. In 2003, a widely cited study conducted by the celiac research center placed the number of people with celiac disease in the U.S. at one in 133.

 

As the people in the study aged, the incidence of celiac disease rose, echoing the findings of a 2008 Finnish study in Digestive and Liver Disease that found the prevalence of celiac disease in the elderly to be nearly two and a half times higher than the general population. The recent findings challenge the common speculation that the loss of gluten tolerance resulting in the disease usually develops in childhood.

 

“You’re not necessarily born with celiac disease,” says Carlo Catassi, M.D., of the Universita Politecnica delle Marche in Italy. Dr. Catassi is the lead author of the paper and co-director of the Center for Celiac Research. “Our findings show that some people develop celiac disease quite late in life.” The trend is supported by clinical data from the center, notes Dr. Catassi, who urges physicians to consider screening their elderly patients.

 

Although researchers have identified specific genetic markers for the development of celiac disease, exactly how and why an individual loses tolerance to gluten remains a mystery. “Even if you have these genetic markers, it’s not your destiny to develop an autoimmune disease,” adds Dr. Fasano. “Our study shows that environmental factors cause an individual’s immune system to lose tolerance to gluten, given the fact that genetics was not a factor in our study since we followed the same individuals over time.”

 

The finding contradicts the common wisdom that nothing can be done to prevent autoimmune disease unless the triggers that cause autoimmunity are identified and removed. Gluten is one of the triggers for celiac disease. But if individuals can tolerate gluten for many decades before developing celiac disease, some environmental factor or factors other than gluten must be in play, notes Dr. Fasano.

 

Identifying and manipulating those factors could lead to novel treatment and possible prevention of celiac disease and other autoimmune disorders including type 1 diabetes, rheumatoid arthritis and multiple sclerosis. Researchers at the University of Maryland Center for Celiac Research are working toward that goal, says Dr. Fasano. As the third most common disease category after cancer and heart disease, autoimmune disorders affect approximately five to eight percent of the U.S. population, according to the National Institutes of Health.

 

“The groundbreaking research of Dr. Fasano and his team sheds new light on the development of celiac disease, a complex disorder that continues to present challenges to physicians and their patients,” says E. Albert Reece, M.D., Ph.D., M.B.A, vice president for medical affairs, University of Maryland, and John Z. and Akiko K. Bowers Distinguished Professor and dean, University of Maryland School of Medicine.

 

Diagnosis of celiac disease can be a challenge as patients who test positive for the disease may not display the classic symptoms of gastrointestinal distress linked to the disease. Atypical symptoms include joint pain, chronic fatigue and depression. In the study, only 11 percent of people identified as positive for celiac disease autoimmunity through blood samples had actually been diagnosed with the disease.

 

Public release date: 28-Sep-2010

 

Sparkling drinks spark pain circuits

 

Fizzy beverages light up same pain sensors as mustard and horseradish, a new study shows — so why do we drink them?

 

You may not think of the fizz in soda as spicy, but your body does.

 

The carbon dioxide in fizzy drinks sets off the same pain sensors in the nasal cavity as mustard and horseradish, though at a lower intensity, according to new research from the University of Southern California.

 

“Carbonation evokes two distinct sensations. It makes things sour and it also makes them burn. We have all felt that noxious tingling sensation when soda goes down your throat too fast,” said Emily Liman, senior author of a study published online in the Journal of Neuroscience.

 

That burning sensation comes from a system of nerves that respond to sensations of pain, skin pressure and temperature in the nose and mouth.

 

“What we did not know was which cells and which molecules within those cells are responsible for the painful sensation we experience when we drink a carbonated soda,” said Liman, an associate professor of neurobiology in the USC College of Letters, Arts and Sciences.

 

By flowing carbonated saline onto a dish of nerve cells from the sensory circuits in the nose and mouth, the researchers found that the gas activated only a particular type of cell.

 

“The cells that responded to CO2 were the same cells that detect mustard,” Liman said.

 

These cells express a gene known as TRPA1 and serve as general pain sensors.

 

Mice missing the TRPA1 gene showed “a greatly reduced response” to carbon dioxide, Liman said, while adding the TRPA1 genetic code to CO2-insensitive cells made them responsive to the gas.

 

Now that carbonated beverages have been linked to pain circuits, some may wonder why we consume them. A new park in Paris even features drinking fountains that dispense free sparkling water.

 

Liman cited studies going back as far as 1885 that found carbonation dramatically reduced the growth of bacteria.

 

“Or it may be a macho thing,” she speculated.

 

If only a sip of San Pellegrino were all it took to prove one’s hardiness.

 

The pain-sensing TRPA1 provides only one aspect of carbonation’s sensory experience. In 2009, a group led by Charles Zuker of the University of California, San Diego and Nicholas Ryba of the National Institutes of Health showed that carbonation trips cells in the tongue that convey sourness.

 

Public release date: 29-Sep-2010

 

Maternal diet high in trans fats doubles risk of excess body fat in breastfed babies, study finds

 

Athens, Ga. – A new University of Georgia study suggests that mothers who consume a diet high in trans fats double the likelihood that their infants will have high levels of body fat.

 

Researchers, whose results appear in the early online edition of the European Journal of Clinical Nutrition, found that infants whose mothers consumed more than 4.5 grams of trans fats per day while breastfeeding were twice as likely to have high percentages of body fat, or adiposity, than infants whose mothers consumed less than 4.5 grams per day of trans fats.

 

The researchers investigated different fatty acids, but determined trans fats to be the most important contributor to excess body fat. “Trans fats stuck out as a predictor to increased adiposity in both mothers and their babies,” said study co-author Alex Anderson, assistant professor in the UGA College of Family and Consumer Sciences.

 

Anderson explained that although breast milk is optimal for the health of infants, it could also contain high levels of trans fats, depending on the mother’s diet. A better understanding of how a mother’s consumption of trans fats may impact the health of her baby would aid nutritionists in making more accurate dietary recommendations to prevent chronic disease later in life by encouraging mothers to select a diet low in trans fats, he said.

 

To determine the effect of the intake of trans fats by the child through breast milk, the researchers studied three different groups; mothers who only breast fed their infants, those that only used formula and those that used a combination of breast milk and formula.

 

It is important to measure body fat in addition to weight, said Anderson, since being overweight does not always mean having a high percent of body fat and vice versa. “It’s not just the weight, but the amount of body fat in the person that affects their health,” Anderson said. “That is why adiposity is such an important measure of cardiovascular risk.”

 

The researchers also found that mothers who consumed more than 4.5 grams of trans fats per day increased their own risk of excessive fat accumulation, independent of pre-pregnancy weight, by almost six times. This data suggests that trans fats intake could have a more significant weight-gain effect on breastfeeding mothers than it does at other times in their lives, Anderson said.

 

The researchers studied 96 women, many of whom were highly educated non-Hispanic white women, and note that the study should be replicated in a larger, more diverse group to strengthen information about the health dangers of eating trans fats. “It would help to be able to follow the child from when the mother was pregnant, through birth, and then adolescence, so that we can confirm what the type of infant feeding and maternal diet during breastfeeding have to do with the recent epidemic of childhood obesity,” said Anderson.

 

Maternal diet high in trans fats doubles risk of excess body fat in breastfed babies, study finds

Athens, Ga. – A new University of Georgia study suggests that mothers who consume a diet high in trans fats double the likelihood that their infants will have high levels of body fat.

 

Researchers, whose results appear in the early online edition of the European Journal of Clinical Nutrition, found that infants whose mothers consumed more than 4.5 grams of trans fats per day while breastfeeding were twice as likely to have high percentages of body fat, or adiposity, than infants whose mothers consumed less than 4.5 grams per day of trans fats.

 

The researchers investigated different fatty acids, but determined trans fats to be the most important contributor to excess body fat. “Trans fats stuck out as a predictor to increased adiposity in both mothers and their babies,” said study co-author Alex Anderson, assistant professor in the UGA College of Family and Consumer Sciences.

 

Anderson explained that although breast milk is optimal for the health of infants, it could also contain high levels of trans fats, depending on the mother’s diet. A better understanding of how a mother’s consumption of trans fats may impact the health of her baby would aid nutritionists in making more accurate dietary recommendations to prevent chronic disease later in life by encouraging mothers to select a diet low in trans fats, he said.

 

To determine the effect of the intake of trans fats by the child through breast milk, the researchers studied three different groups; mothers who only breast fed their infants, those that only used formula and those that used a combination of breast milk and formula.

 

It is important to measure body fat in addition to weight, said Anderson, since being overweight does not always mean having a high percent of body fat and vice versa. “It’s not just the weight, but the amount of body fat in the person that affects their health,” Anderson said. “That is why adiposity is such an important measure of cardiovascular risk.”

 

The researchers also found that mothers who consumed more than 4.5 grams of trans fats per day increased their own risk of excessive fat accumulation, independent of pre-pregnancy weight, by almost six times. This data suggests that trans fats intake could have a more significant weight-gain effect on breastfeeding mothers than it does at other times in their lives, Anderson said.

 

The researchers studied 96 women, many of whom were highly educated non-Hispanic white women, and note that the study should be replicated in a larger, more diverse group to strengthen information about the health dangers of eating trans fats. “It would help to be able to follow the child from when the mother was pregnant, through birth, and then adolescence, so that we can confirm what the type of infant feeding and maternal diet during breastfeeding have to do with the recent epidemic of childhood obesity,” said Anderson.

 

Public release date: 29-Sep-2010

 

Garlic oil shows protective effect against heart disease in diabetes

 

Garlic has “significant” potential for preventing cardiomyopathy, a form of heart disease that is a leading cause of death in people with diabetes, scientists have concluded in a new study. Their report, which also explains why people with diabetes are at high risk for diabetic cardiomyopathy, appears in ACS’ bi-weekly Journal of Agricultural and Food Chemistry.

 

Wei-Wen Kuo and colleagues note that people with diabetes have at least twice the risk of death from heart disease as others, with heart disease accounting for 80 percent of all diabetes-related deaths. They are especially vulnerable to a form of heart disease termed diabetic cardiomyopathy, which inflames and weakens the heart’s muscle tissue. Kuo’s group had hints from past studies that garlic might protect against heart disease in general and also help control the abnormally high blood sugar levels that occur in diabetes. But they realized that few studies had been done specifically on garlic’s effects on diabetic cardiomyopathy.

 

The scientists fed either garlic oil or corn oil to laboratory rats with diabetes. Animals given garlic oil experienced beneficial changes associated with protection against heart damage. The changes appeared to be associated with the potent antioxidant properties of garlic oil, the scientists say, adding that they identified more than 20 substances in garlic oil that may contribute to the effect. “In conclusion, garlic oil possesses significant potential for protecting hearts from diabetes-induced cardiomyopathy,” the report notes.

 

Public release date: 29-Sep-2010

 

Blueberries help fight artery hardening, lab animal study indicates

 

Blueberries may help fight atherosclerosis, also known as hardening of the arteries, according to results of a preliminary U.S. Department of Agriculture (USDA)-funded study with laboratory mice. The research provides the first direct evidence that blueberries can help prevent harmful plaques or lesions, symptomatic of atherosclerosis, from increasing in size in arteries.

 

Principal investigator Xianli Wu, based in Little Rock, Ark., with the USDA Agricultural Research Service (ARS) Arkansas Children’s Nutrition Center and with the University of Arkansas for Medical Sciences, led the investigation. The findings are reported in the current issue of the Journal of Nutrition.

 

Atherosclerosis is the leading cause of two forms of cardiovascular disease–heart attacks and strokes. Cardiovascular disease is the number one killer of Americans.

 

The study compared the size, or area, of atherosclerotic lesions in 30 young laboratory mice. Half of the animals were fed diets spiked with freeze-dried blueberry powder for 20 weeks; the diet of the other mice did not contain the berry powder.

 

Lesion size, measured at two sites on aorta (arteries leading from the heart), was 39 and 58 percent less than that of lesions in mice whose diet did not contain blueberry powder.

 

Earlier studies, conducted elsewhere, have suggested that eating blueberries may help combat cardiovascular disease. But direct evidence of that effect has never been presented previously, according to Wu.

 

The blueberry-spiked diet contained 1 percent blueberry powder, the equivalent of about a half-cup of fresh blueberries.

 

All mice in the investigation were deficient in apolipoprotein-E, a trait which makes them highly susceptible to forming atherosclerotic lesions and thus an excellent model for biomedical and nutrition research.

 

Wu’s group wants to determine the mechanism or mechanisms by which blueberries helped control lesion size. For example, by boosting the activity of four antioxidant enzymes, blueberries may have reduced the oxidative stress that is a known risk factor for atherosclerosis.

 

In followup studies, Wu’s group wants to determine whether eating blueberries in infancy, childhood and young adulthood would help protect against onset and progression of atherosclerosis in later years. Early prevention may be especially important in light of the nation’s epidemic of childhood obesity. Overweight and obesity increase atherosclerosis risk.

 

Public release date: 29-Sep-2010

 

IU researchers: Chemotherapy alters brain tissue in breast cancer patients

 

INDIANAPOLIS — Researchers at the Indiana University Melvin and Bren Simon Cancer Center have published the first report using imaging to show that changes in brain tissue can occur in breast cancer patients undergoing chemotherapy.

 

The cognitive effects of chemotherapy, often referred to as “chemobrain,” have been known for years. However, the IU research is the first to use brain imaging to study women with breast cancer before and after treatment, showing that chemotherapy can affect gray matter. The researchers reported their findings in the October 2010 edition of Breast Cancer Research and Treatment.

 

“This is the first prospective study,” said Andrew Saykin, Psy.D., director of the Indiana University Center for Neuroimaging and a researcher at the IU Simon Cancer Center. “These analyses, led by Brenna McDonald, suggest an anatomic basis for the cognitive complaints and performance changes seen in patients. Memory and executive functions like multi-tasking and processing speed are the most typically affected functions and these are handled by the brain regions where we detected gray matter changes.”

 

Dr. Saykin, who is Raymond C. Beeler Professor of Radiology at the IU School of Medicine, and colleagues studied structural MRI scans of the brain obtained on breast cancer patients and healthy controls. The scans were taken after surgery, but before radiation or chemotherapy, to give the researchers a baseline. Scans were then repeated one month and one year after chemotherapy was completed.

 

The researchers found gray matter changes were most prominent in the areas of the brain that are consistent with cognitive dysfunction during and shortly after chemotherapy. Gray matter density in most women improved a year after chemotherapy ended.

 

For many patients, Dr. Saykin said, the effects are subtle. However, they can be more pronounced for others. Although relatively rare, some patients — often middle-aged women — are so affected that they are never able to return to work. More commonly, women will still be able to work and multi-task, but it may be more difficult to do so.

 

The study focused on 17 breast cancer patients treated with chemotherapy after surgery, 12 women with breast cancer who did not undergo chemotherapy after surgery, and 18 women without breast cancer.

 

“We hope there will be more prospective studies to follow so that the cause of these changes in cancer patients can be better understood,” Dr. Saykin said.

 

Dr. Saykin and his colleagues started their research at Dartmouth Medical School before finishing the data analyses at IU. A new, independent sample is now being studied at the IU Simon Cancer Center to replicate and further investigate this problem affecting many cancer patients.

 

Public Release: 29-Sep-2010

 

Dirty hands, dirty mouths: U-M study finds a need to clean the body part that lies

 

ANN ARBOR, Mich.—Apparently your mom had it right when she threatened to wash your mouth out with soap if you talked dirty. Lying really does create a desire to clean the “dirty” body part, according to a University of Michigan study.

 

“The references to ‘dirty hands’ or ‘dirty mouths’ in everyday language suggest that people think about abstract issues of moral purity in terms of more concrete experiences with physical purity,” said Spike W.S. Lee, a U-M doctoral candidate in psychology, who conducted the study with Norbert Schwarz, a psychologist at the U-M Institute for Social Research (ISR), the Ross School of Business, and the U-M psychology department.

 

The findings of the study, published in the current (October) issue of Psychological Science, support that connection.

 

For the study, Lee and Schwarz asked 87 students to play the role of lawyers competing with a colleague, “Chris,” for a promotion. Each was asked to imagine they found an important document that Chris had lost, and that returning the document would help his career and hurt their own career. Each participant was instructed to leave Chris a message by either voice mail or email, telling him who they were and either lying that they could not find his document or telling the truth that they had found the document.

 

Next, participants rated the desirability of several products as part of a supposed marketing survey and reported how much they were willing to pay for each product. The products included mouthwash and hand sanitizer.

 

Study participants who lied on the phone, leaving an untrue and malevolent voicemail, felt a stronger desire for mouthwash and were willing to pay more for it than those who lied on e-mail. And conversely, those who lied on e-mail, typing the same mean message, felt a stronger desire for hand sanitizer and were willing to pay more for that. Saying nice and ethical things, on the other hand, made it less appealing to clean the body part involved in conveying the message.

 

In scientific terms, the findings showed that “the embodiment of moral purity is specific to the motor modality involved in the moral transgression.” Verbal lying increased participants’ assessment of mouthwash while lying on e-mail, using their hands, increased the assessment of hand sanitizer’s value.

 

“This study shows how ‘concrete’ the metaphorical links are between abstract and concrete domains of life,” Schwarz said. “Not only do people want to clean after a dirty deed, they want to clean the specific body part involved.”

 

Public release date: 29-Sep-2010

 

Research examines vicious cycle of overeating and obesity

 

New research provides evidence of the vicious cycle created when an obese individual overeats to compensate for reduced pleasure from food.

 

Obese individuals have fewer pleasure receptors and overeat to compensate, according to a study by University of Texas at Austin senior research fellow and Oregon Research Institute senior scientist Eric Stice and his colleagues published this week in The Journal of Neuroscience.

 

Stice shows evidence this overeating may further weaken the responsiveness of the pleasure receptors (“hypofunctioning reward circuitry”), further diminishing the rewards gained from overeating.

 

Food intake is associated with dopamine release. The degree of pleasure derived from eating correlates with the amount of dopamine released. Evidence shows obese individuals have fewer dopamine (D2) receptors in the brain relative to lean individuals and suggests obese individuals overeat to compensate for this reward deficit.

 

People with fewer of the dopamine receptors need to take in more of a rewarding substance — such as food or drugs — to get an effect other people get with less.

 

“Although recent findings suggested that obese individuals may experience less pleasure when eating, and therefore eat more to compensate, this is the first prospective evidence to show that the overeating itself further blunts the award circuitry,” says Stice, a senior scientist at Oregon Research Institute, a non-profit, independent behavioral research center. “The weakened responsivity of the reward circuitry increases the risk for future weight gain in a feed-forward manner. This may explain why obesity typically shows a chronic course and is resistant to treatment.”

 

Using Functional Magnetic Resonance Imaging (fMRI), Stice’s team measured the extent to which a certain area of the brain (the dorsal striatum) was activated in response to the individual’s consumption of a taste of chocolate milkshake (versus a tasteless solution). Researchers tracked participants’ changes in body mass index over six months.

 

Results indicated those participants who gained weight showed significantly less activation in response to the milkshake intake at six-month follow-up relative to their baseline scan and relative to women who did not gain weight.

 

“This is a novel contribution to the literature because, to our knowledge, this is the first prospective fMRI study to investigate change in striatal response to food consumption as a function of weight change,” said Stice. “These results will be important when developing programs to prevent and treat obesity.”

 

Public release date: 30-Sep-2010

 

Dog ownership is associated with reduced eczema in children with dog allergies

 

Cincinnati, OH, September 30, 2010 — Children with eczema, a chronic skin condition that often begins in childhood, have a greater risk of developing asthma and food allergies. The number of children with eczema is rising, but the reasons for this are unclear. A new study soon to be published in The Journal of Pediatrics examines the relationship between pet ownership and eczema. Researchers found that dog ownership among children with dog allergies may reduce the risk of developing eczema by age 4 years; cat ownership, however, may increase the risk among children with cat allergies.

 

Dr. Tolly Epstein and colleagues from the University of Cincinnati and Cincinnati Children’s Hospital Medical Center gathered data from 636 children enrolled in the Cincinnati Childhood Allergy & Air Pollution Study (CCAAPS), a long-term epidemiologic study examining the effects of environmental particulates on childhood respiratory health and allergy development. Children enrolled in the study are considered at high risk for developing allergies because they were born to parents with allergies. The researchers focused on several potential risk factors for developing eczema, including dog and cat ownership. The children were tested for 17 separate allergies on a yearly basis from ages 1 through 4 years, and the parents completed yearly surveys.

 

The results provided interesting information regarding pet ownership. The researchers found that children who tested positive for dog allergies were less likely to develop eczema by age 4 years if they owned a dog before age 1 year. According to Dr. Epstein, “Children with dog allergies who did not own dogs were 4 times more likely to develop eczema.”

 

Unlike dog ownership, cat ownership seemed to have a negative effect on children with cat allergies. “Children who owned a cat before age 1 year and were allergic to cats based on a skin allergy test were 13 times more likely to develop eczema by age 4 years,” Dr. Epstein explains. She notes, however, that children who were not allergic to cats were not at an increased risk for eczema if they owned a cat. Dr. Epstein suggests that parents of children at risk for eczema may want to consider these findings when choosing a family pet.

 

Public release date: 30-Sep-2010

 

Faith in God associated with improved survival after liver transplantation

 

Study reveals religiosity prolongs life span

 

Italian researchers report that liver transplant candidates who have a strong religious connection have better post-transplant survival. This study also finds that religiosity—regardless of cause of death—prolongs the life span of individuals who underwent liver transplantation. Full findings are now available online and in the October issue of Liver Transplantation. a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases (AASLD).

 

Much of the medical profession today is focused on the delivery of services, rather than whole patient care which not only takes into account physical well-being, but psychological, social, and spiritual aspects as well. Although there is a lack of interest in religion by the medical community, the authors point out that 90% of the world’s population today is involved in some form of religion or spiritual pursuit. Prior studies have demonstrated that religiosity allows individuals to better cope with illness, and may even influence disease progression. Furthermore, a report by McCullough et al. that included a meta-analysis of 42 studies (surveying roughly 126,000 people) found active religious involvement increased the odds of being alive at follow-up by 26%.

 

“Our study tested the hypothesis that religiosity—seeking God’s help, having faith in God, trusting in God, trying to discern God’s will even in the disease—improves survival of patients with end-stage liver disease who underwent liver transplantation,” explains Franco Bonaguidi, D.Psych., and lead author of the study. The study team selected 179 patients who received a liver transplant between January 2004 and December 2007, and who also completed the religiosity questionnaire. Participants (129 males and 50 females) had a media age of 52 years and were followed for 4 years (median = 21 months) post-transplantation. Indications for liver transplant included: viral hepatitis (68%), alcoholic liver disease (17%), and autoimmune hepatitis (7%).

 

Results indicate that the Search for God factor (hazard ratio = 2.95) and length of stay in the intensive care unit (1.05) were independently associated with survival. Furthermore, it was the personal relationship between the patient and God, regardless of religious creed (Christian, Muslim, or other) rather than formal church attendance that positively affected survival. As one participant described, “I recovered my life by the will of Someone up there…I had great faith in Him. This closeness made me feel strong and calm.”

 

Dr. Bonaguidi concluded, “We found that an active search for God—the patient’s faith in a higher power rather than a generic destiny—had a positive impact on patient survival.” The authors caution that this study focuses on a severely ill patient population, therefore the conclusions may not be applicable to individuals with different illnesses or degrees of disease severity.

 

Public release date: 30-Sep-2010

 

Drugs for low libido raise concerns over industry ‘construction’ of new diseases

 

Feature: Merging of marketing and medical science: female sexual dysfunction

 

Drug companies have not only sponsored the science of a new condition known as female sexual dysfunction, they have helped to construct it, in order to build global markets for new drugs, reveals an article in this week’s BMJ.

 

Researching his new book ‘Sex, Lies and Pharmaceuticals’ Ray Moynihan, journalist and lecturer at the University of Newcastle in Australia, discovered that drug industry employees have worked with paid key opinion leaders to help develop the disease entity; they have run surveys to portray it as widespread; and they helped design diagnostic tools to persuade women that their sexual difficulties deserve a medical label and treatment.

 

He believes that “drug marketing is merging with medical science in a fascinating and frightening way” and he asks whether we need a fresh approach to defining disease.

 

He quotes a company employee saying that her company was interested in “expediting the development of a disease” and he reveals how companies are funding surveys that portray sexual problems as widespread and creating tools to assess women for “hypoactive sexual desire disorder.”

 

Many of the researchers involved in these activities were drug company employees or had financial ties to the industry, writes Moynihan. Meanwhile, scientific studies conducted without industry funding were questioning whether a widespread disorder of low desire really existed.

 

Industry is also taking a leading role in “educating” both professionals and the public about this controversial condition, he adds.

 

For example, a Pfizer funded course designed for doctors across the United States claimed that up to 63% of women had sexual dysfunction and that testosterone and sildenafil (Viagra) may be helpful, along with behavioural therapy. And he points out that German drug company Boehringer Ingelheim’s “educational” activities “went into overdrive” as the planned 2010 launch of its desire drug, flibanserin, approached.

 

In June, flibanserin was rejected by advisors to the US Food and Drug Administration and Pfizer’s sildenafil was also pulled after studies showed virtually no difference from placebo. But although the drugs have so far failed, Moynihan warns that “the edifice of scientific evidence about the condition remains in place … creating the impression that there is a massive “unmet need” for treatment.”

 

And with more experimental drugs in the pipeline, “the drug industry shows no signs of abandoning plans to meet the unmet need it has helped to manufacturer,” he says.

 

“Perhaps it’s time to reassess the way in which the medical establishment defines common conditions and recommends how to treat them,” he suggests.

 

“Perhaps it is time to develop new panels to take responsibility for defining treatable illness, made up of people without financial ties to those with vested interests in the outcomes of their deliberations and much more broadly representative of the wider public … and start the slow process of untangling the marketing from the medical science.” he concludes.

 

“Faced with a woman in tears whose libido has disappeared and who is terrified of losing her partner, doctors can feel immense pressure to provide an immediate, effective solution,” says Dr Sandy Goldbeck-Wood, a specialist in psychosexual medicine, in an accompanying commentary.

 

She says Moynihan’s research clarifies both the conflicts of interest at work and the relative paucity of good quality evidence for pharmacological solutions to women’s sexual problems. However, she argues: “his argument that female sexual dysfunction is an illness constructed by pathologising doctors under the influence of drug companies will fail to convince clinicians who see women with sexual dysfunction, or their patients.”

 

Women who have struggled to overcome the psychological and cultural barriers to requesting help with their sexual difficulties will not welcome the argument that they are to be “left alone,” she writes.

 

She believes the problem is one of oversimplification and believes that more studies are needed that reflect the complexity of sexual life. “It’s time to invest in more research into the most realistic, respectful and evidence based treatments, rather than narrow biological ones founded on poor evidence,” she says.

 

Public release date: 30-Sep-2010

 

Bioethics scholars fault requirement that all women in clinical drug trials use contraception

 

(Garrison, NY) Research ethics review committees often require all women of childbearing age who enroll in clinical trials to use contraceptives to protect against a developing fetus being exposed to potentially harmful drugs. A mandatory contraceptive policy is often imposed even when there is no evidence that a trial drug could harm a fetus or when women have no chance of becoming pregnancy. This requirement is excessive and can safely be relaxed in many cases, according to a report in IRB: Ethics & Human Research.

 

Policies on contraceptive use in research should reflect the level of potential risk the study drug poses to the fetus, write Chris Kaposy, an assistant professor of Health Care Ethics at Memorial University of Newfoundland, Canada; and Françoise Baylis, professor and Canada Research Chair in Bioethics and Philosophy at Dalhousie University in Halifax. They point to the U.S. Food and Drug Administration’s categories for prescription drug labeling for drug use in pregnancy as a helpful guide. The FDA has five categories, each with different degrees of evidence of risk to fetuses.

 

Category A, for example, indicates that “adequate, well-controlled studies in pregnant women have not shown increased risk of fetal abnormalities.” And yet the policy of the University of Nebraska Medical Center’s institutional review board – which Kaposy and Baylis reviewed as a typical example of IRB contraceptive use policies – permits researchers to petition the IRB to impose a mandatory contraception or abstinence requirement for trial participants in studies that use Category A drugs. However, the authors argue that an ideal policy for Category A drugs would not require contraception or abstinence.

 

The authors also say that contraception should not be mandated for women who have no chance of becoming pregnant while participating in a clinical drug trial. “Consider, for example, women who are not sexually active (e.g., nuns) or who are not sexually active in a heterosexual relationship (e.g., lesbians),” they write. Mandating contraception for these groups sends “a paternalistic message of mistrust” that undermines the normal practice of treating research participants as autonomous decision-makers.

 

“Our recommendations are an attempt to find an appropriate balance between the interests of potential fetuses and the autonomy and well-being of women,” they write.

 

Public release date: 30-Sep-2010

 

J&J, FDA leaders take heat for ‘phantom’ recall

 

By MATTHEW PERRONE, AP Health Writer Matthew Perrone, Ap Health Writer

Thu Sep 30, 5:58 pm ET

 

WASHINGTON – Johnson & Johnson executives and the Food and Drug Administration both shouldered the blame Thursday for a secret recall in which hired contractors quietly bought up defective painkillers to clear them from store shelves.

 

J&J Chief Executive William Weldon told House lawmakers the company “made a mistake” in conducting the so-called “phantom recall,” which is one of a string of problems that have drawn congressional scrutiny

 

In the same committee hearing, the FDA’s deputy commissioner, Dr. Joshua Sharfstein, said his agency should have acted sooner to halt J&J’s plan. At the same time, though, he stressed that regulators were not aware of the deceptive nature of the recall.

 

Sharfstein and Weldon testified before the House Committee on Oversight and Government Reform, which held its second hearing on J&J’s unprecedented spate of recalls. The largest, involving more than 135 million bottles of infants’ and children’s Tylenol and other medicines, triggered the committee’s investigation.

 

“We recognize that we need to do better, and we will work hard to restore the public’s trust and faith in Johnson & Johnson,” Weldon told lawmakers.

 

Democrats and Republicans pressed Weldon on its “phantom” recall involving 88,000 packets of Motrin, which Weldon acknowledged as “not one of our finer moments.”

 

But lawmakers also pressed the FDA on when and what it knew about the activity. New Brunswick, N.J.-based J&J has repeatedly claimed it alerted the agency’s officials in Puerto Rico, where the defective Motrin was originally manufactured.

 

Sharfstein said J&J informed the FDA of its plan to repurchase the pills – which did not dissolve correctly – in April 2009.

 

“From this point, it took until July for the FDA to tell the company that a recall should be conducted,” Sharfstein said in his testimony. “In my opinion that message should have been given sooner.”

 

But Sharfstein stressed that the FDA did not know J&J had instructed contractors to pose as regular customers while buying the product and to not alert store employees to their activity.

 

“Based on the documents I reviewed, I don’t see any indication that the FDA was aware of the surreptitious, lying nature of the recall,” he said.

 

Republican lawmakers criticized a “too cozy” relationship between FDA and J&J employees, citing months-long e-mail exchanges between the two before regulators took action. But Sharfstein said ultimate blame lies with J&J, pointing out that the FDA does not have the authority to order when and how companies conduct recalls.

 

“I think fundamentally the responsibility is with the company to handle their quality problems in a much different way,” Sharfstein said.

 

Companies are advised to work with the FDA on recalls, although that isn’t a legal requirement.

 

Committee Chairman Edolphus Towns, D-N.Y., has introduced a bill that would give the agency the power to order recalls.

 

The maker of trusted brands like Tylenol and Benadryl, J&J has announced nine recalls of drugs for children and adults since last September with problems ranging from too much active ingredient to tiny shards of metal.

 

In May, J&J closed its Fort Washington, Pa., facility, the largest manufacturing site for children’s medications. J&J announced Thursday it would begin shipping its grape-flavored Children’s Tylenol next week, the first of its children’s formulas to return to the market.

 

Weldon said the company plans to invest $100 million across the company to improve facilities, equipment and operations around the world.

 

Weldon, who has been CEO since 2002, missed the committee’s last hearing because of back surgery.

 

Testifying beside him Thursday was J&J executive Colleen Goggins, who oversaw the consumer division of the company’s McNeil Healthcare unit during the recalls.

 

At the May hearing, Goggins told lawmakers she had no knowledge of instructions to contractors involved in the phantom recall to not tell store employees what they were doing. In her testimony Thursday, Goggins acknowledged that the company wrote those instructions.

 

“Based on what I have learned since May, I believe that McNeil should have handled things differently,” Goggins said.

 

Goggins will retire in March, Johnson & Johnson announced this month.

 

Ralph’s Note – If all the product did was not dissolve correctly….Then why the incredible secrecy, and deception? I’m sorry.. First the FDA and J&J admit being dishonest….Then they issue this weak press release. Yes the FDA may not of had the authoity to issue a recall…BUT IT IS THEIR JOB TO AT LEAST INFORM THE PUBLIC.. Now that all the recalled tablets have been secretly REMOVED AS EVIDENCE….How will we ever know the TRUTH. Whatever Tablets remain, need to go to an independent testing facility…. WHY are no lot numbers mentioned in this article? They are probably still sitting in medicine cabinets across the country….

 

Public release date: 1-Oct-2010

 

Vitamin D levels lower in African-Americans

 

MIAMI — African-American women had lower vitamin D levels than white women, and vitamin D deficiency was associated with a greater likelihood for aggressive breast cancer, according to data presented at the Third AACR Conference on the Science of Cancer Health Disparities.

 

“We know that darker skin pigmentation acts somewhat as a block to producing vitamin D when exposed to sunlight, which is the primary source of vitamin D in most people,” said Susan Steck, Ph.D., M.P.H., associate professor of epidemiology at the University of South Carolina.

 

Steck and colleagues observed 107 women who were all diagnosed with breast cancer in the previous five years. Sixty of these women were African-American, while the remaining 47 were white.

 

All women donated a blood sample, and vitamin D status was determined using circulating 25 hydroxyvitamin D levels as a marker. The mean serum concentration of vitamin D was 29.8 ng/ml in white women and 19.3 ng/ml in African-American women.

 

Researchers defined vitamin D deficiency as a serum concentration less than 20 ng/ml, and found this to be the case in 60 percent of African-American women compared with 15 percent of white women. Serum levels were lowest among patients with triple-negative breast cancer, and aggressive disease was eight times more likely among patients with vitamin D deficiency.

 

Steck said the findings of this study provide a foundation for a possible prevention strategy, but further research would be required.

 

Public release date: 1-Oct-2010

 

Vigorous exercise reduces breast cancer risk in African-American women

 

MIAMI — Vigorous exercise of more than two hours per week reduces the risk of developing breast cancer in postmenopausal African-American women by 64 percent, compared to women of the same race who do not exercise, according to researchers at Georgetown Lombardi Comprehensive Cancer Center.

 

Results were presented at the Third AACR Conference on The Science of Cancer Health Disparities, held Sept. 30 to Oct. 3, 2010.

 

“People often want to know what they can do to reduce their risk of disease, and we have found that just two or more hours of vigorous activity per week can made a difference in one’s risk of developing breast cancer,” said the lead researcher Vanessa Sheppard, Ph.D., a cancer control scientist and assistant professor in the department of oncology at the Lombardi Comprehensive Cancer Center.

 

In this study, more than two hours of aerobics, running or similar activity over the span of a week counted as vigorous activity.

 

“We also know from other studies that being physically active can have benefits in other diseases that occur at high rates in African-American women, such as diabetes and hypertension,” Sheppard said. “Four out of five African-American women are either overweight or obese, and disease control is a particularly important issue for them.”

 

Evidence showing exercise reduces breast cancer risk has been inconsistent, and there are few that look specifically at African-American women, Sheppard said. The issue is important, she added, because breast cancer has some important differences in this community. Whereas more white women are diagnosed with breast cancer, African-American women have a higher risk of developing premenopausal breast cancer than white women do, and comparatively more African-American women develop the most aggressive form of the disease, known as triple-negative breast cancer.

 

The researchers identified 97 recently diagnosed African-American breast cancer patients in the Washington, D.C., area and matched them with 102 African-American women without breast cancer. Participants filled out a questionnaire about exercise routines; the responses were analyzed and compared.

 

Women who exercised vigorously for more than two hours a week in the past year had a 64 percent reduced risk of breast cancer compared to women who did not exercise. Women who engaged in moderate exercise, like walking, had a 17 percent reduced risk, compared to women who were sedentary.

 

After evaluating those who were pre- and postmenopausal, they found that vigorous exercise only significantly benefitted postmenopausal women — they had a 62 percent reduction in risk.

 

“I was surprised that we did not find a significant effect in premenopausal women, but it may be because we need a larger sample,” Sheppard said.

 

However, when the researchers examined the effect of total physical activity, which combined walking with vigorous activity of two or more hours per week, they saw significant gains for both premenopausal and postmenopausal women.

 

“We suggest that our findings, while promising, should be interpreted with caution. This is a pilot study and a larger, more rigorous study is needed to precisely quantify the effect of exercise on development of breast cancer. I think it is fair to conclude that if African American women exercise they can help take charge of their health,” said Sheppard.

 

Public release date: 1-Oct-2010

 

Think saturated fat contributes to heart disease? Think again

 

Leading scientists re-examine the role of saturated fat in the diet

(Rosemont, IL) Oct. 1 – For the past three decades, saturated fat has been considered a major culprit of cardiovascular disease (CVD) and as a result dietary advice persists in recommending reduced consumption of this macronutrient. However, new evidence shows that saturated fat intake has only a very limited impact on CVD risk — causing many to rethink the “saturated fat is bad” paradigm.

 

A series of research articles published in the October issue of Lipids provides a snapshot of recent advances in saturated fat and health research, based on science presented at the 100th American Oil Chemists’ Society (AOCS) annual meeting in Orlando, Florida (May 2009). During a symposium entitled “Saturated Fats and Health: Facts and Feelings,” world-renowned scientists specializing in fat research analyzed the evidence between saturated fat intake and health, and overall agreed upon the need to reduce over-simplification when it came to saturated fat dietary advice.

 

“The relationship between dietary intake of fats and health is intricate, and variations in factors such as human genetics, life stage and lifestyles can lead to different responses to saturated fat intake,” said J. Bruce German, PhD, professor and chemist in the Department of Food Science and Technology, University of California at Davis. “Although diets inordinately high in fat and saturated fat are associated with increased cardiovascular disease risk in some individuals, assuming that saturated fat at any intake level is harmful is an over-simplification and not supported by scientific evidence.”

 

Professor Philippe Legrand of Agrocampus-INRA in France confirmed this by discussing various roles that different saturated fatty acids play in the body. His main conclusion was that saturated fats can no longer be considered a single group in terms of structure, metabolism and cellular function, and recommendations that group them together with regard to health effects need to be updated.

 

Effect of Saturated Fat Replacement on CVD Risk

 

Results from a research review conducted by Dariush Mozaffarian, MD, MPH, Department of Epidemiology and Nutrition at Harvard University School of Public Health, found that the effects of saturated fat intake on CVD risk depend upon simultaneous changes in other nutrients. For example, replacing saturated fat with mono-unsaturated fat yielded uncertain effects on CVD risk, while replacing saturated fat with carbohydrates was found to be ineffective and even harmful especially when refined carbohydrates such as starches or sugars were used in place of fat . Replacing saturated fat with polyunsaturated fat gave a small reduction in CVD risk, but even with optimal replacement the magnitude of the benefit was very small. According to Mozaffarian it would be far better to focus on dietary factors giving much larger benefits for CVD health, such as increasing intake of seafood/omega-3 fatty acids, whole grains, fruits and vegetables, and decreasing intake of trans fats and sodium.

 

”Carbohydrate intake has been intimately linked to metabolic syndrome, which is a combination of risk factors that can increase CVD risk,” said Jeff Volek, PhD, RD, Department of Kinesiology, University of Connecticut. His research showed that very low carbohydrate diets can favorably impact a broad spectrum of metabolic syndrome and cardiovascular risk factors, even in the presence of high saturated fat intake and in the absence of weight loss.

 

Kiran Musunuru, MD, PhD, MPH. Cardiovascular Research Center and Center for Human Genetic Research, Massachusetts General Hospital, focused on the role of carbohydrates and fats on atherogenic dyslipidemia – a new marker for CVD risk often seen in patients with obesity, metabolic syndrome, insulin resistance and type 2 diabetes. He showed that low-carbohydrate diets appear to have beneficial lipoprotein effects in individuals with atherogenic dyslipidemia, compared to high-carbohydrate diets, whereas the content of saturated fat in the diet has no significant effect.

 

Full-Fat Dairy: An Unnecessary Target?

 

As long as saturated fat targets remain firmly rooted in dietary advice, nutrient-rich foods that contribute saturated fat to the diet, like full-fat dairy products, will continue to be unduly criticized regardless of their health benefits.

 

A recent meta-analysis of epidemiological and intervention studies of milk fat conducted by Peter Elwood, DSc, MD, FRCP, FFPHM, DUniv, Hon DSc, Honorary Professor at the School of Medicine, Cardiff University, found that milk and dairy consumption actually was associated with a decrease in CVD risk .

 

“It is clear that we have barely scratched the surface in our understanding about the biological effects of saturated fatty acids,” said Cindy Schweitzer, PhD, Technical Director, Global Dairy Platform. “Scientific meetings where researchers from different disciplines within the field of nutrition share information are extremely important to identify both the gaps in our knowledge and the studies that are needed to answer the important questions about diet and health.”

 

All of these recent research advances add to the growing body of science re-assessing the role of saturated fat in the diet. Whether it’s nutrient replacement or better understanding the role certain foods can play in CVD risk, saturated fat is definitely not be as bad as once thought.

 

Public release date: 4-Oct-2010

 

Sleep loss limits fat loss

 

Cutting back on sleep reduces the benefits of dieting, according to a study published October 5, 2010, in the Annals of Internal Medicine.

 

When dieters in the study got a full night’s sleep, they lost the same amount of weight as when they slept less. When dieters got adequate sleep, however, more than half of the weight they lost was fat. When they cut back on their sleep, only one-fourth of their weight loss came from fat.

 

They also felt hungrier. When sleep was restricted, dieters produced higher levels of ghrelin, a hormone that triggers hunger and reduces energy expenditure.

 

“If your goal is to lose fat, skipping sleep is like poking sticks in your bicycle wheels,” said study director Plamen Penev, MD, PhD, assistant professor of medicine at the University of Chicago. “Cutting back on sleep, a behavior that is ubiquitous in modern society, appears to compromise efforts to lose fat through dieting. In our study it reduced fat loss by 55 percent.”

 

The study, performed at the University of Chicago’s General Clinical Resource Center, followed 10 overweight but healthy volunteers aged 35 to 49 with a body mass index ranging from 25, considered overweight, to 32, considered obese. Participants were placed on an individualized, balanced diet, with calories restricted to 90 percent of what each person needed to maintain his or her weight without exercise.

 

Each participant was studied twice: once for 14 days in the laboratory with an 8.5-hour period set aside for sleep, and once for 14 days with only 5.5 hours for sleep. They spent their waking hours engaged in home- or office-like work or leisure activities.

 

During the two-week, 8.5-hours-in-bed phase, volunteers slept an average of 7 hours and 25 minutes each night. In the 5.5-hour phase, they slept 5 hours and 14 minutes, or more than two hours less. The number of calories they consumed, about 1,450 per day, was kept the same.

 

The volunteers lost an average of 6.6 pounds during each 14-day session. During weeks with adequate sleep, they lost 3.1 pounds of fat and 3.3 pounds of fat-free body mass, mostly protein. During the short-sleep weeks, participants lost an average of 1.3 pounds of fat and 5.3 pounds of fat-free mass.

 

Getting adequate sleep also helped control the dieters’ hunger. Average levels of ghrelin did not change when dieters spent 8.5 hours in bed. When they spent 5.5 hours in bed, their ghrelin levels rose over two weeks from 75 ng/L to 84 ng/L.

 

Higher ghrelin levels have been shown to “reduce energy expenditure, stimulate hunger and food intake, promote retention of fat, and increase hepatic glucose production to support the availability of fuel to glucose dependent tissues,” the authors note. “In our experiment, sleep restriction was accompanied by a similar pattern of increased hunger and … reduced oxidation of fat.”

 

The tightly controlled circumstances of this study may actually have masked some of sleep’s benefits for dieters, suggested Penev. Study subjects did not have access to extra calories. This may have helped dieters to “stick with their lower-calorie meal plans despite increased hunger in the presence of sleep restriction,” he said.

 

The message for people trying to lose weight is clear, Penev said. “For the first time, we have evidence that the amount of sleep makes a big difference on the results of dietary interventions. One should not ignore the way they sleep when going on a diet. Obtaining adequate sleep may enhance the beneficial effects of a diet. Not getting enough sleep could defeat the desired effects.”

 

Public release date: 4-Oct-2010

 

Walnuts, walnut oil, improve reaction to stress

 

A diet rich in walnuts and walnut oil may prepare the body to deal better with stress, according to a team of Penn State researchers who looked at how these foods, which contain polyunsaturated fats, influence blood pressure at rest and under stress.

 

Previous studies have shown that omega-3 fatty acids — like the alpha linolenic acid found in walnuts and flax seeds — can reduce low density lipoproteins (LDL) — bad cholesterol. These foods may also reduce c-reactive protein and other markers of inflammation.

 

“People who show an exaggerated biological response to stress are at higher risk of heart disease,” said Sheila G. West, associate professor of biobehavioral health. “We wanted to find out if omega 3-fatty acids from plant sources would blunt cardiovascular responses to stress.”

 

The researchers studied 22 healthy adults with elevated LDL cholesterol. All meals and snacks were provided during three diet periods of six weeks each.

 

The researchers found that including walnuts and walnut oil in the diet lowered both resting blood pressure and blood pressure responses to stress in the laboratory. Participants gave a speech or immersed their foot in cold water as a stressor. Adding flax seed oil to the walnut diet did not further lower blood pressure. They report their findings in the current issue of the Journal of the American College of Nutrition.

 

“This is the first study to show that walnuts and walnut oil reduce blood pressure during stress,” said West. “This is important because we can’t avoid all of the stressors in our daily lives. This study shows that a dietary change could help our bodies better respond to stress.”

 

A subset of the participants also underwent a vascular ultrasound in order to measure artery dilation. Results showed that adding flax oil to the walnut diet significantly improved this test of vascular health. The flax plus walnuts diet also lowered c-reactive protein, indicating an anti-inflammatory effect. According to West, that could also reduce risk of cardiovascular disease.

 

The researchers used a randomized, crossover study design. Tests were conducted at the end of each six-week diet, and every participant consumed each of the three diets in random order, with a one-week break between. Diets included an “average” American diet – a diet without nuts that reflects what the typical person in the U.S. consumes each day. The second diet included 1.3 ounces of walnuts and a tablespoon of walnut oil substituted for some of the fat and protein in the average American diet. The third diet included walnuts, walnut oil and 1.5 tablespoons of flaxseed oil. The three diets were matched for calories and were specifically designed for each participant so that no weight loss or gain occurred. The walnuts, walnut oil, and flax oil were either mixed into the food in such offerings as muffins or salad dressing or eaten as a snack. About 18 walnut halves or 9 walnuts make up the average serving used by the researchers.

After each diet, the participants underwent two stress tests. In the first test, they received a topic; and they were given two minutes to prepare a three-minute speech, which they presented while being videotaped. The second stressor was a standard physical test of stress consisting of submerging one foot in ice-cold water. Throughout these tests, the researchers took blood pressure readings from the participants.

 

Results showed that average diastolic blood pressure — the “bottom number” or the pressure in the arteries when the heart is resting — was significantly reduced during the diets containing walnuts and walnut oil.

 

Walnuts are a rich source of fiber, antioxidants, and unsaturated fatty acids, particularly alpha linolenic acid, an omega-3 fatty acid, and these compounds could be responsible for the beneficial effects on blood pressure. Flax oil is a more concentrated source of omega-3 fatty acids than walnut oil, but this study did not test whether flax oil alone could blunt cardiovascular responses to stress.

 

“These results are in agreement with several recent studies showing that walnuts can reduce cholesterol and blood pressure,” noted West. “This work suggests that blood pressure is also reduced when a person is exposed to stress in their daily life.”

 

Public release date: 4-Oct-2010

 

Surprise: Scientists discover that inflammation helps to heal wounds

 

New research in the FASEB Journal suggests that muscle inflammation after acute muscle injury is essential to muscle repair by means of insulin-like growth factor-1

A new research study published in The FASEB Journal (http://www.fasebj.org) may change how sports injuries involving muscle tissue are treated, as well as how much patient monitoring is necessary when potent anti-inflammatory drugs are prescribed for a long time. That’s because the study shows for the first time that inflammation actually helps to heal damaged muscle tissue, turning conventional wisdom on its head that inflammation must be largely controlled to encourage healing. These findings could lead to new therapies for acute muscle injuries caused by trauma, chemicals, infections, freeze damage, and exposure to medications which cause muscle damage as a side effect. In addition, these findings suggest that existing and future therapies used to combat inflammation should be closely examined to ensure that the benefits of inflammation are not eliminated.

 

“We hope that our findings stimulate further research to dissect different roles played by tissue inflammation in clinical settings, so we can utilize the positive effects and control the negative effects of tissue inflammation,” said Lan Zhou, M.D., Ph.D., a researcher involved in the work from the Neuroinflammation Research Center/Department of Neurosciences/Lerner Research Institute at the Cleveland Clinic in Ohio.

 

Zhou and colleagues found that the presence of inflammatory cells (macrophages) in acute muscle injury produce a high level of a growth factor called insulin-like growth factor-1 (IGF-1) which significantly increases the rate of muscle regeneration. The research report shows that muscle inflammatory cells produce the highest levels of IGF-1, which improves muscle injury repair. To reach this conclusion, the researchers studied two groups of mice. The first group of mice was genetically altered so they could not mount inflammatory responses to acute injury. The second group of mice was normal. Each group experienced muscle injury induced by barium chloride. The muscle injury in the first group of mice did not heal, but in the second group, their bodies repaired the injury. Further analysis showed that macrophages within injured muscles in the second group of mice produced a high level of IGF-1, leading to significantly improved muscle repair.

 

“For wounds to heal we need controlled inflammation, not too much, and not too little,” said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal, “It’s been known for a long time that excess anti-inflammatory medication, such as cortisone, slows wound healing. This study goes a long way to telling us why: insulin-like growth factor and other materials released by inflammatory cells helps wound to heal.”

 

Public release date: 5-Oct-2010

 

Amino acid supplement makes mice live longer

 

When mice are given drinking water laced with a special concoction of amino acids, they live longer than your average mouse, according to a new report in the October issue of Cell Metabolism, a Cell Press publication. The key ingredients in the supplemental mixture are so-called branched-chain amino acids, which account for 3 of the 20 amino acids (specifically leucine, isoleucine, and valine) that are the building blocks of proteins.

 

“This is the first demonstration that an amino acid mixture can increase survival in mice,” said Enzo Nisoli of Milan University in Italy, noting that researchers last year showed that leucine, isoleucine, and valine extend the life span of single-celled yeast.

 

In the new study, the researchers gave middle-aged, male mice extra branched-chain amino acids (BCAA) in their drinking water. The animals were otherwise healthy and eating standard mouse chow.

 

Animals that were given the extra amino acids over a period of months lived longer, with a median life span of 869 days compared to 774 days for untreated control animals, the researchers report. That’s an increase of 12 percent.

 

Those survival gains were accompanied by an increase in mitochondria in cardiac and skeletal muscles. Mitochondria are the cellular components responsible for powering cells. The supplement-fed mice also showed increased activity of SIRT1, a well-known longevity gene, and of the defense system that combats free radicals. They therefore showed fewer signs of oxidative damage.

 

The benefits of the amino acid supplements appear similar to those earlier ascribed to calorie restriction, Nisoli said.

 

Treated animals also showed improvements in their exercise endurance and in motor coordination, the researchers report. (It is important to note that the animals in the current study were all male, Nisoli said. They plan to test the effects in females in future studies.)

 

The findings in older mice suggest that the supplementary mixture may be specifically beneficial for those who are elderly or ill. “It may not be useful in young people or body builders,” who are already in good condition, he said. But it might be a useful preventive strategy, he added, emphasizing that the mice they studied “were just aged, not sick.”

 

Nisoli emphasized that consuming amino acid supplements is different from consuming proteins containing those amino acids. That’s because they do not have to be digested, and can enter the bloodstream immediately. “They come with no energy cost.”

 

He suspects that BCAA nutritional supplements may prove to be particularly helpful for people with heart failure, the muscle-wasting condition known as sarcopenia, chronic obstructive pulmonary disease, or other conditions characterized by energy defects. In fact, there are already some small studies in human to support that idea and BCAA supplements are already available for purchase in several countries, including Italy.

 

The challenge, Nisoli says, will be convincing clinicians that these supplements might be a benefit to their patients. He says a large clinical trial is needed, but there is little incentive for companies to do such trials for dietary supplements as opposed to drugs.

 

Overall, Nisoli said the new work supports a “general philosophy of a nutritional approach to disease, aging, and problems of energy status.”

 

Public release date: 5-Oct-2010

 

Shortfalls in carotenoid ( Pro-Vitamin A )intake may impact women’s health

 

Newly released report finds younger women have greater ‘carotenoid gap’ in the diet than older women

GRAND RAPIDS, MICH., Oct. 5, 2010 – Only about a third of American women are meeting their fruit and vegetable intake recommendations, which means they are likely missing out on potentially important breast and ovarian health benefits (1). Along with vitamins, minerals and fiber, fruits and vegetables contain a type of phytonutrient called carotenoids, which research suggests help support women’s health including breast and ovarian health.

 

Based on a new report called America’s Phytonutrient Report: Women’s Health by Color, older women have total carotenoid intakes 20 percent greater than younger women after accounting for differences in caloric intake. Similar to the original America’s Phytonutrient Report: Quantifying the Gap which found that on average eight out of 10 American adults are falling short on phytonutrient consumption, the new report revealed a troubling shortfall, this time among women and carotenoids. America’s Phytonutrient Reports are released by The Nutrilite Health Institute, a worldwide collaboration of experts who are dedicated to helping people achieve optimal health – through research, education, and practical, personalized solutions. Nutrilite is the world’s leading brand of vitamin, mineral, and dietary supplements, based on 2008 sales.

 

Carotenoids are compounds that give fruits and vegetables their vibrant colors, which research suggests may offer breast, ovarian and other health benefits for women. Using NHANES energy-adjusted data to compare the diets of women 45 years and older with those younger, the report finds that many women of all ages lack carotenoid-rich foods in their diet, but the relative magnitude of the “carotenoid gap” is greater among women less than 45 years old as compared to older women.

 

“This points to a troubling phenomenon where younger women may be missing some of the benefits of consuming more carotenoid rich fruits and vegetables, and yet calorie for calorie, older women are eating more of these important nutrients,” said Keith Randolph, Ph.D., Technology Strategist for Nutrilite.

 

The Carotenoids by Color Category

 

This new report examined consumption of five different carotenoids across three phytonutrient color categories including alpha-carotene, beta-carotene and beta-cryptoxanthin in the yellow/orange category, lutein/zeaxanthin in the green category and lycopene in red. In every color category, older women consumed equal or greater amounts compared to younger women after adjusting for differences in caloric intake. Specifically, women age 45 and older consume:

 

•50 percent more beta-carotene;

•40 percent more alpha-carotene and lutein/zeaxanthin;

•and, 10 percent more beta-cryptoxanthin.

For lycopene, younger and older women consume comparable amounts.

 

Carotenoids Shown To Reduce Cancer Risk

 

A growing body of research suggests carotenoids may be associated with protective benefits against certain cancers. The research points to an apparent lowered risk for breast and ovarian cancers among women of all ages who increase their intake of fruits and vegetables rich in various carotenoids including lutein/zeaxanthin, lycopene, alpha-carotene, beta-carotene and beta-cryptoxanthin according to Randolph.

 

Top Food Sources

 

It turns out that a limited number of foods account for significant portions of carotenoid intakes, according to the new report. Following are the single largest food contributors in the diets of American women by color category of phytonutrient:

 

•Green Carotenoid: Lutein/Zeaxanthin

 

◦Spinach accounts for 33% of lutein/zeaxanthin intake among younger women and 31% among older.

•Red Carotenoid: Lycopene

 

◦Tomatoes (and tomato products) account for 93% of lycopene intake among younger women and 89% among older.

•Yellow/Orange Carotenoid: Alpha-carotene

 

◦Carrots account for 76% of alpha-carotene intake among younger women and 73% among older.

•Yellow/Orange Carotenoid: Beta-carotene

 

◦Carrots account for 33% of beta-carotene intake among younger women and 30% among older.

•Yellow/Orange Carotenoid: Beta-cryptoxanthin

 

◦Oranges (and orange juice) account for 61% of beta-cryptoxanthin intake among younger women and 60% among older.

Powering Up Produce

 

Choosing to increase the amount of the fruit and vegetables richest in carotenoids is important for long-term preventative health among women. While foods like spinach, tomatoes and carrots are certainly part of a healthy diet, there are opportunities for women to choose a wider variety of produce. For example, while carrots are among the top food sources of alpha and beta-carotenes, cooked pumpkin is also a concentrated food source of not only those carotenes, but of beta-cryptoxanthin. However, based on the current data analysis, cooked pumpkin accounts for less than 3% of total intake of these carotenoids among American women.

 

“It’s concerning that so many American women lack a variety of carotenoid-rich foods in their regular diets,” says Amy Hendel, Nutrilite’s Phytonutrient Coach. “By selecting the most carotenoid-rich produce choices, women can purposefully increase their carotenoid and phytonutrient intakes which can impact health significantly as they age.”

 

Hendel, a registered physician assistant and health/wellness expert, offers these easy substitutions to “power up” your plate and add new flavors to your meal plan:

 

•Green: A serving of cooked kale provides triple the amount of lutein/zeaxanthin as a serving of raw spinach.

•Red: A serving of guava delivers more than one and a half times the lycopene in a raw tomato.

•Yellow/Orange:

◦A serving of sweet potatoes has nearly double the beta-carotene as a serving of carrots.

◦A serving of carrots delivers four times the amount of alpha-carotene as a serving of winter squash.

◦A serving of fresh papaya has roughly 10 times the beta-cryptoxanthin found in an orange.

 

Hendel adds, a good goal for most individuals is to consume 10 servings of fruits and vegetables daily, with an emphasis on quality, not just quantity. If this proves challenging, consider a natural, plant-based dietary supplement which includes phytonutrients such as carotenoids.

 

“Just remember, small changes in the diet each day can add up to powerful changes over time. Older women may eat more carotenoids, but women of all ages are falling short. Diet is a lifetime of exposure and best we teach younger women how to eat right, up those carotenoids, and exercise more from the beginning,” says Hendel.

 

Public release date: 5-Oct-2010

 

Low Testosterone Linked to Alzheimer’s Disease

 

SLU Geriatrician Collaborates on Year-Long Study of Chinese Older Men

 

ST. LOUIS — Low levels of the male sex hormone, testosterone, in older men is associated with the onset of Alzheimer’s disease, according to research by a team that includes a Saint Louis University scientist.

 

John Morley, M.D.

 

“Having low testosterone may make you more vulnerable to Alzheimer’s disease,” said John E. Morley, M.D., director of the division of geriatric medicine at Saint Louis University and a study co-investigator. “The take-home message is we should pay more attention to low testosterone, particularly in people who have memory problems or other signs of cognitive impairment.”

 

The study was published electronically prior to its print publication in the Journal of Alzheimer’s Disease and led by Leung-Wing Chu, M.D., who is chief of the division of geriatric medicine at Queen Mary Hospital at the University of Hong Kong.

 

Researchers studied 153 Chinese men who were recruited from social centers. They were at least 55 years and older, lived in the community and didn’t have dementia. Of those men, 47 had mild cognitive impairment – or problems with clear thinking and memory loss.

 

Within a year, 10 men who all were part of the cognitively impaired group developed probable Alzheimer’s disease. These men also had low testosterone in their body tissues; elevated levels of the ApoE 4 (apolipoprotein E) protein, which is correlated with a higher risk of Alzheimer’s disease; and high blood pressure.

 

“It’s a very exciting study because we’ve shown that a low level of testosterone is one of the risk factors for Alzheimer’s disease,” Morley said.

 

The findings corroborate findings in previous studies of older Caucasian men that show low testosterone is associated with impaired thinking and Alzheimer’s disease. They suggest that testosterone may have a protective value against Alzheimer’s disease.

 

The next step, Morley said, is to conduct a large-scale study that investigates the use of testosterone in preventing Alzheimer’s disease. Morley and his co-authors advocate studying the effectiveness of testosterone replacement in older men who have both mild memory problems and low testosterone in staving off Alzheimer’s disease.

 

Public release date: 6-Oct-2010

 

Vitamin D deficiency rampant in patients undergoing orthopedic surgery, damaging patient recovery

 

Doctors provide strategy to improve outcomes

 

Almost 50 percent of patients undergoing orthopedic surgery have vitamin D deficiency that should be corrected before surgery to improve patient outcomes, based on a study by researchers at Hospital for Special Surgery (HSS) in New York City. Vitamin D is essential for bone healing and muscle function and is critical for a patient’s recovery. The study appears in the October issue of The Journal of Bone and Joint Surgery.

 

“In the perfect world, test levels, fix and then operate,” said Joseph Lane, M.D., professor of Orthopedic Surgery and chief of the Metabolic Bone Disease Service at HSS, who led the study. “If you put people on 2,000-4,000 [milligrams] of vitamin D based on what their deficient value was, you can usually get them corrected in four to six weeks, which is when you are really going to need the vitamin D. If you are really aggressive right before surgery, you can correct deficient levels quickly, but you have to correct it, measure it, and then act on it.”

 

According to Dr. Lane, bone remodeling or bone tissue formation, a part of the healing process, occurs about two to four weeks after surgery. This is the critical stage when your body needs vitamin D.

 

For their study, investigators conducted a retrospective chart review of 723 patients who were scheduled for orthopedic surgery between January 2007 and March 2008 at HSS. They examined the vitamin D levels, which had been measured in all patients before their surgery, and found that 43 percent had insufficient vitamin D and 40 percent had deficient levels.

 

Vitamin D inadequacy was defined as

 

The highest levels of deficiency were seen in patients in the trauma service, where 66 percent of patients had insufficient levels and 52 percent had deficient levels. Of the patients undergoing foot and ankle surgery, 34 percent had inadequate levels and of patients undergoing hand surgery, 40 percent had insufficient levels.

 

In the Sports Medicine Service, 52.3 percent had insufficient levels and of these, one-third of these or 17 percent of the total had deficient levels. “We frequently see stress fractures in the Sports Medicine Service and if you want to heal, you have to fix the calcium and vitamin D,” Dr. Lane said.

 

In the Arthroplasty Service, which conducts hip and knee replacements, 38 percent had inadequate levels and 48 percent had deficient levels. “With arthroplasty, there is a certain number of patients that when you put in the prothesis, it breaks the bone adjacent to the protheses, which can really debilitate patients.” This could be prevented or minimized by rectifying vitamin D levels. Dr. Lane also explained that they now perform procedures where they grow a bone into a prosthesis without using cement. “In those people, it would be an advantage to have adequate vitamin D, because it matures the bone as it grows in, it is really healing into the prosthesis,” he said.

 

“The take home message is that low vitamin D has an implication in terms of muscle and fracture healing, it occurs in about 50 percent of people coming in for orthopedic surgery, and it is eminently correctable,” Dr. Lane said. “We recommend that people undergoing a procedure that involves the bone or the muscle should correct their vitamin D if they want to have an earlier faster, better, result. What we are saying is ‘wake up guys, smell the coffee; half of your patients have a problem, measure it, and if they are low, then fix it.'”

 

In recent years, vitamin D deficiency has been recognized as a common phenomenon and is caused by many factors. It is difficult to get from foods, except, for example, cod liver oil and fish. Until recently, the recommended daily allowance was set too low so foods were not supplemented with adequate doses. And third, while people can absorb vitamin D from sunlight, people these days often work long hours and often use sunscreen that impedes vitamin D intake.

 

________________________________

These reports are done with the appreciation of all the Doctors, Scientist, and other

Medical Researchers who sacrificed their time and effort. In order to give people the

ability to empower themselves. Without the base aspirations for fame, or fortune.

Just honorable people, doing honorable things.

 

86th Health Research Report 05 AUG 2010 – Reconstruction

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Health Research Report

86th Issue 05 AUG 2010

Compiled By Ralph Turchiano

www.vit.bz

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Editors Top Picks;

1. Of bugs and brains: Caltech researchers discover that gut bacteria affect multiple sclerosis

2. Probiotic use in mothers limits eczema in their babies

3. Research links recreational pool disinfectants to health problems

4. Non-human sugar in biotech drugs causes inflammation

5. Natural substance NT-020 aids aging brains in rats, USF study finds

In this Issue;

1. Tea contains more fluoride than once thought

2. Cashew seed extract an effective anti-diabetic

3. Several studies support the role of choline in fetal development and throughout the lifespan

4. More than half the world’s population gets insufficient vitamin D, says UCR biochemist

5. American Academy of Family Physicians – Coca-Cola Alliance, Conflict of Interest or Ethical Relationship?

6. Of bugs and brains: Caltech researchers discover that gut bacteria affect multiple sclerosis

7. Do cleaning products cause breast cancer?

8. Painters at significantly increased risk of bladder cancer

9. UT researchers: English ivy may give sunblock a makeover

10. Natural substance NT-020 aids aging brains in rats, USF study finds

11. Probiotic use in mothers limits eczema in their babies

12. Asthma and eczema sufferers have a lower risk of developing a cancer

13. Research links recreational pool disinfectants to health problems

14. New evidence that chili pepper ingredient fights fat

15. Could diabetes be in your bones?

16. Vitamins needed to help celiacs stave off bone disease

17. Non-human sugar in biotech drugs causes inflammation

18. Alcohol reduces the severity of rheumatoid arthritis

19. Western diet link to ADHD

20. Research by UB’s Paresh Dandona and colleagues points to the anti-inflammatory effects of the plant compound resveratrol.

Public release date: 14-Jul-2010

Tea contains more fluoride than once thought

AUGUSTA, Ga. – Black tea, a Southern staple and the world’s most consumed beverage, may contain higher concentrations of fluoride than previously thought, which could pose problems for the heaviest tea drinkers, Medical College of Georgia researchers say.

“The additional fluoride from drinking two to four cups of tea a day won’t harm anyone; it’s the very heavy tea drinkers who could get in trouble,” said Dr. Gary Whitford, Regents Professor of oral biology in the School of Dentistry. He presented his findings today at the 2010 International Association of Dental Research Conference in Barcelona, Spain.

Most published reports show 1 to 5 milligrams of fluoride per liter of black tea, but a new study shows that number could be as high as 9 milligrams.

Fluoride is known to help prevent dental cavities, but long-term ingestion of excessive amounts could cause bone problems. The average person ingests a very safe amount, 2 to 3 milligrams, daily through fluoridated drinking water, toothpaste and food. It would take ingesting about 20 milligrams a day over 10 or more years before posing a significant risk to bone health.

Whitford discovered that the fluoride concentration in black tea had long been underestimated when he began analyzing data from four patients with advanced skeletal fluorosis, a disease caused by excessive fluoride consumption and characterized by joint and bone pain and damage. While it is extremely rare in the United States, the common link between these four patients was their tea consumption – each person drank 1 to 2 gallons of tea daily for the past 10 to 30 years.

“When we tested the patients’ tea brands using a traditional method, we found the fluoride concentrations to be very low, so we wondered if that method was detecting all of the fluoride,” Whitford said, noting that the tea plant, Camellia sinensis, creates a quandary when measuring fluoride. Unique among other plants, it accumulates huge concentrations of fluoride and aluminum in its leaves – each mineral ranges from 600 to more than 1,000 milligrams per kilogram of leaves. When the leaves are brewed for tea, some of the minerals leach into the beverage.

Most published studies about black tea traditionally have used a method of measuring fluoride that doesn’t account for the amount that combines with aluminum to form insoluble aluminum fluoride, which is not detected by the fluoride electrode. Whitford compared that method with a diffusion method, which breaks the aluminum-fluoride bond so that all fluoride in the tea samples can be extracted and measured.

He tested seven brands of store-bought black tea, steeping each for five minutes in deionized water, which contains no fluoride. The amount of fluoride in each sample was 1.4 to 3.3 times higher using the diffusion method than the traditional method.

The new information shouldn’t deter tea drinkers, as the beverage is safe and some teas even have health benefits, Whitford said. “The bottom line is to enjoy your favorite tea, but like everything else, drink it in moderation.”

Including Whitford’s presentation, School of Dentistry faculty and students will make 24 oral and poster presentations at the International Association for Dental Research conference July 14-17.

Public release date: 14-Jul-2010

Cashew seed extract an effective anti-diabetic

New study published in Molecular Nutrition and Food Research journal

Montreal, July 14, 2010 – Cashew seed extract shows promise as an effective anti-diabetic, according to a new study from the University of Montreal (Canada) and the Université de Yaoundé (Cameroun). Published in the journal Molecular Nutrition & Food Research, the investigation analyzed the reputed health benefits of cashew tree products on diabetes, notably whether cashew extracts could improve the body’s response to its own insulin.

Diabetes is caused when a person has high blood sugar because their body does not respond well to insulin and/or does not produce enough of the hormone. The illness, which affects nearly 220 million people worldwide, can provoke heart or kidney disease. The goal of the study was to examine the impact of leaves, bark, seeds and apples from cashew trees, native to northeastern Brazil and other countries of the southern hemisphere, on cells that respond to insulin.

“Of all the extracts tested, only cashew seed extract significantly stimulated blood sugar absorption by muscle cells,” says senior author Pierre S. Haddad, a pharmacology professor at the University of Montreal’s Faculty of Medicine. “Extracts of other plant parts had no such effect, indicating that cashew seed extract likely contains active compounds, which can have potential anti-diabetic properties.”

Cashew tree products have long been alleged to be effective anti-inflammatory agents, counter high blood sugar and prevent insulin resistance among diabetics. “Our study validates the traditional use of cashew tree products in diabetes and points to some of its natural components that can serve to create new oral therapies,” adds Dr. Haddad, who is also director of the Canadian Institutes of Health Research Team in Aboriginal Anti-Diabetic Medicines at the University of Montreal.

Public release date: 15-Jul-2010

Several studies support the role of choline in fetal development and throughout the lifespan

Essential nutrient in eggs may reduce risk of infant heart defects

A study published in the American Journal of Clinical Nutrition found that a choline-deficient diet is associated with increased risk for heart defects during prenatal development.1 Choline is an essential nutrient required for normal cell activity, healthy brain and nerve function, liver metabolism and transportation of nutrients throughout the body. Research shows that only 10 percent or less of older children, men, women and pregnant women in America are meeting the Adequate Intake (AI) levels for choline; despite a growing body of science which supports the importance of choline especially in healthy fetal development.2

Vital Role of Choline During Pregnancy

A growing body of science, conducted in both animals and humans, supports the need for more dietary choline. Researchers from McGill University and Cornell University examined the offspring of mice that consumed a choline-deficient diet during pregnancy compared to the offspring of mice that consumed a diet containing the recommended amount of choline. The researchers observed that heart defects were more prevalent among the offspring of mice consuming a choline-deficient diet. The study also found that low choline intake was associated with increased levels of homocysteine, an amino acid in the blood that, when elevated, is associated with an increased risk of cardiovascular disease and declined cognitive function.

“Choline is a complex nutrient that is intricately involved in fetal development, and this research reveals another piece of the puzzle,”according to Cornell University Associate Professor, Marie Caudill, Ph.D., R.D. “Women with diets low in choline have two times greater risk of having babies with neural tube defects so it’s essential that nutrition education during pregnancy and breastfeeding highlight the importance of dietary sources of choline.”

Another study, published in the June issue of Behavioral Neuroscience, reported that choline intake during pregnancy and lactation is associated with improved attention function.3 The researchers observed that offspring of female mice consuming a diet supplemented with choline during pregnancy and lactation performed significantly better on attention tasks compared to offspring from mothers consuming a diet not supplemented with choline.

The Importance of Choline Throughout the Lifespan

Another study published in the American Journal of Clinical Nutrition examined adult dietary intake of choline and betaine (a nutrient related to choline) and found that higher intakes of choline and betaine were associated with lower blood homocysteine concentrations, especially in subjects with low blood levels of folate and vitamin B12.4 Choline, like folate, is involved in breaking down homocysteine in the blood. Elevated homocysteine concentrations have been associated with increased risk of stroke, coronary heart disease and cognitive decline.

In May, a study published online in the Journal of Nutrition reported on the role of choline in the complex system that regulates DNA production and stability. Researchers studied the impact of choline intake on DNA damage in 60 Mexican-American men. They found that individuals with greater intakes of choline, even exceeding current dietary recommendations, exhibited the least amount of DNA damage.5

Focusing on a Choline-Rich Diet

“Choline is important for people of all ages, particularly moms and moms-to-be,” says Neva Cochran, M.S., R.D., nutrition communications consultant and nutrition writer and researcher for Woman’s World magazine. “It is easy to meet the recommended choline intake with delicious foods like an egg, which is an excellent source of choline and provides roughly one-quarter of a pregnant or breastfeeding woman’s choline needs.”

Cochran recommends the following choline-rich meal ideas as part of a balanced diet:

•Basic Hard-Cooked Eggs – Prepare a batch of hard-cooked eggs on Sunday to have, high-quality protein meals and snacks on hand throughout the week which is especially important for moms-to-be.

•Cereal Bowl Egg & Cheese Breakfast Burrito – Try this microwavable burrito bowl topped with cheese and salsa – a quick, easy breakfast that can be enjoyed in seconds.

•Basic Frittata – Make fillings from your favorite foods or from leftovers. Use a combination of meat, seafood or poultry, cheese, vegetables and cooked pasta or grains.

###

Choline Resources

•To learn more about choline and to download free educational materials, visit http://www.cholineinfo.org.

•To learn more about prenatal nutrition and download a free copy of the Pregnancy Food Guide, visit http://www.pregnancyfoodguide.org/.

•For more information on the nutritional benefits of eggs, visit the Egg Nutrition Center at http://www.enc-online.org.

•For additional choline-rich egg recipes and preparation tips, visit the American Egg Board at http://www.incredibleegg.org.

About the American Egg Board (AEB)

AEB is the U.S. egg producer’s link to the consumer in communicating the value of The incredible edible egg™ and is funded from a national legislative checkoff on all egg production from companies with greater than 75,000 layers, in the continental United States. The board consists of 18 members and 18 alternates from all regions of the country who are appointed by the Secretary of Agriculture. The AEB staff carries out the programs under the board direction. AEB is located in Park Ridge, Ill. Visit http://www.IncredibleEgg.org for more information.

Public release date: 15-Jul-2010

More than half the world’s population gets insufficient vitamin D, says UCR biochemist

Vitamin D expert Anthony Norman recommends a daily intake of 2000 international units for most adults

RIVERSIDE, Calif. – Vitamin D surfaces as a news topic every few months. How much daily vitamin D should a person get? Is it possible to have too much of it? Is exposure to the sun, which is the body’s natural way of producing vitamin D, the best option? Or do supplements suffice?

In the July 2010 issue of Endocrine Today, a monthly newspaper published by SLACK, Inc., to disseminate information about diabetes and endocrine disorders, Anthony Norman, a distinguished professor emeritus of biochemistry and biomedical sciences and an international expert on vitamin D, notes that half the people in North America and Western Europe get insufficient amounts of vitamin D.

“Elsewhere, it is worse,” he says, “given that two-thirds of the people are vitamin D-insufficient or deficient. It is clear that merely eating vitamin D-rich foods is not adequate to solve the problem for most adults.”

Currently, the recommended daily intake of vitamin D is 200 international units (IU) for people up to 50 years old; 400 IU for people 51 to 70 years old; and 600 IU for people over 70 years old.

“There is a wide consensus among scientists that the relative daily intake of vitamin D should be increased to 2,000 to 4,000 IU for most adults,” Norman says. “A 2000 IU daily intake can be achieved by a combination of sunshine, food, supplements, and possibly even limited tanning exposure.”

While there is now abundant data on vitamin D and its benefits, Norman believes there is room for more study.

“The benefits of more research on the topic justifies why this field of research deserves additional governmental funding,” he says. “Already, several studies have reported substantial reductions in incidence of breast cancer, colon cancer and type 1 diabetes in association with adequate intake of vitamin D, the positive effect generally occurring within five years of initiation of adequate vitamin D intake.”

Because vitamin D is found in very few foods naturally (e.g. fish, eggs and cod liver oil) other foods such as milk, orange juice, some yogurts and some breakfast foods are fortified with it. The fortification levels aim at about 400 IU per day.

Norman, who holds the title of Presidential Chair in Biochemistry-Emeritus, has been researching vitamin D for nearly 50 years. In 1967, his laboratory discovered that the vitamin is converted into a steroid hormone by the body. Two years later, his laboratory discovered the vitamin D receptor (or VDR), an essential receptor for the steroid hormone form of vitamin D that is present in more than 37 target organs of the body that respond biologically to the vitamin.

“There is now irrevocable evidence that receptors in the immune, pancreas, heart-cardiovascular, muscle and brain systems in the body generate biological responses to the steroid hormone form of vitamin D,” he says.

 

Public release date: 15-Jul-2010

 

American Academy of Family Physicians – Coca-Cola Alliance, Conflict of Interest or Ethical Relationship?

In an essay addressing the recent controversy over the American Academy of Family Physicians accepting a large corporate donation from The Coca-Cola Company to fund patient education materials on obesity prevention, family physician and AAFP member Howard Brody, M.D., Ph.D., argues that accepting funds from commercial sources that seek to influence physician organization behavior in a direction that could run counter to the public health constitutes a conflict of interest. He asserts that many of the defenses offered by AAFP leadership are rationalizations rather than sound ethical counterarguments. He concludes that medical organizations, as the public face of medicine and as formulators of codes of ethics for their physician members, have special obligations to adhere to high ethical standards, and he raises concern about the development of a corporate culture within a medical professional society. Family physicians, he concludes, have demonstrated a commitment to putting the health needs of their patients ahead of personal financial gain. As such, they deserve to be represented nationally by an organization that fully reflects those high ethical commitments and standards.

In response to the editorial by Howard Brody, M.D., Ph.D., AAFP President, Lori Heim, M.D., F.A.A.F.P., counters in a separate essay that the AAFP’s new consumer alliance agreement with The Coca-Cola Company illustrated the AAFP’s adherence to its ethical foundation, demonstrated the AAFP’s commitment to serving physicians and the public, and maintained the trust Americans put in their family physicians and the organization that represents them. She contends that throughout the development of the program, the AAFP consistently addressed possible conflicts of interest openly and directly, sharing with its members and the public exactly what measures it was taking to ensure that no unethical conduct or breach of trust would occur. The AAFP saw a public health and education need that was both unmet and undermined by the barrage of marketing messages and confusing information and acted to fill that need by developing unbiased educational materials to help patients make good nutrition decisions. In so doing, she concludes, the AAFP hewed to its high ethical standards, its core values, and its mission in the decisions made and the actions that followed.

Ralph’s Note – Yep, no problem here,,,, Next McDonalds weight loss centers..

Public release date: 19-Jul-2010

Of bugs and brains: Caltech researchers discover that gut bacteria affect multiple sclerosis

PASADENA, Calif. —Biologists at the California Institute of Technology (Caltech) have demonstrated a connection between multiple sclerosis (MS)—an autoimmune disorder that affects the brain and spinal cord—and gut bacteria.

The work—led by Sarkis K. Mazmanian, an assistant professor of biology at Caltech, and postdoctoral scholar Yun Kyung Lee—appears online the week of July 19󈞃 in the Proceedings of the National Academy of Sciences.

Multiple sclerosis results from the progressive deterioration of the protective fatty myelin sheath surrounding nerve cells. The loss of myelin hinders nerve cells from communicating with one another, leading to a host of neurological symptoms including loss of sensation, muscle spasms and weakness, fatigue, and pain. Multiple sclerosis is estimated to affect about half a million people in the United States alone, with rates of diagnosis rapidly increasing. There is currently no cure for MS.

Although the cause of MS is unknown, microorganisms seem to play some sort of role. “In the literature from clinical studies, there are papers showing that microbes affect MS,” Mazmanian says. “For example, the disease gets worse after viral infections, and bacterial infections cause an increase in MS symptoms.”

 

On the other hand, he concedes, “it seems counterintuitive that a microbe would be involved in a disease of the central nervous system, because these are sterile tissues.”

And yet, as Mazmanian found when he began examining the multiple sclerosis literature, the suggestion of a link between bacteria and the disease is more than anecdotal. Notably, back in 1993, Caltech biochemist Leroy Hood—who was then at the University of Washington—published a paper describing a genetically engineered strain of mouse that developed a lab-induced form of multiple sclerosis known as experimental autoimmune encephalomyelitis, or EAE.

When Hood’s animals were housed at Caltech, they developed the disease. But, oddly, when the mice were shipped to a cleaner biotech facility—where their resident gut bacterial populations were reduced—they didn’t get sick. The question was, why? At the time, Mazmanian says, “the authors speculated that some environmental component was modulating MS in these animals.” Just what that environmental component was, however, remained a mystery for almost two decades.

But Mazmanian—whose laboratory examines the relationships between gut microbes, both harmful and helpful, and the immune systems of their mammalian hosts—had a hunch that intestinal bacteria were the key. “As we gained an appreciation for how profoundly the gut microbiota can affect the immune system, we decided to ask if symbiotic bacteria are the missing variable in these mice with MS,” he says.

 

To find out, Mazmanian and his colleagues tried to induce MS in animals that were completely devoid of the microbes that normally inhabit the digestive system. “Lo and behold, these sterile animals did not get sick,” he says.

Then the researchers decided to see what would happen if bacteria were reintroduced to the germ-free mice. But not just any bacteria. They inoculated mice with one specific organism, an unculturable bug from a group known as segmented filamentous bacteria. In prior studies, these bacteria had been shown to lead to intestinal inflammation and, more intriguingly, to induce in the gut the appearance of a particular immune-system cell known as Th17. Th17 cells are a type of T helper cell—cells that help activate and direct other immune system cells. Furthermore, Th17 cells induce the inflammatory cascade that leads to multiple sclerosis in animals.

“The question was, if this organism is inducing Th17 cells in the gut, will it be able to do so in the brain and central nervous system?” Mazmanian says. “Furthermore, with that one organism, can we restore to sterile animals the entire inflammatory response normally seen in animals with hundreds of species of gut bacteria?”

The answer? Yes on all counts. Giving the formerly germ-free mice a dose of one species of segmented filamentous bacteria induced Th17 not only in the gut but in the central nervous system and brain—and caused the formerly healthy mice to become ill with MS-like symptoms.

“It definitely shows that gut microbes have a strong role in MS, because the genetics of the animals were the same. In fact, everything was the same except for the presence of those otherwise benign bacteria, which are clearly playing a role in shaping the immune system,” Mazmanian says. “This study shows for the first time that specific intestinal bacteria have a significant role in affecting the nervous system during MS—and they do so from the gut, an anatomical location very, very far from the brain.”

Mazmanian and his colleagues don’t, however, suggest that gut bacteria are the direct cause of multiple sclerosis, which is known to be genetically linked. Rather, the bacteria may be helping to shape the immune system’s inflammatory response, thus creating conditions that could allow the disease to develop. Indeed, multiple sclerosis also has a strong environmental component; identical twins, who possess the same genome and share all of their genes, only have a 25 percent chance of sharing the disease. “We would like to suggest that gut bacteria may be the missing environmental component,” he says.

For their part, Th17 cells are needed for the immune system to properly combat infection. Problems only arise when the cells are activated in the absence of infection—just as disease can arise, Mazmanian and others suspect, when the species composition of gut bacteria become imbalanced, say, by changes in diet, because of improved hygiene (which kills off the beneficial bacteria as well as the dangerous ones), or because of stress or antibiotic use. One impact of the dysregulation of normal gut bacterial populations—a phenomenon dubbed “dysbiosis”—may be the rising rate of multiple sclerosis seen in recent years in more hygienic societies.

“As we live cleaner, we’re not just changing our exposure to infectious agents, but we’re changing our relationship with the entire microbial world, both around and inside us, and we may be altering the balance between pro- and anti-inflammatory bacteria,” leading to diseases like MS, Mazmanian says. “Perhaps treatments for diseases such as multiple sclerosis may someday include probiotic bacteria that can restore normal immune function in the gut… and the brain.”

Public release date: 19-Jul-2010

Do cleaning products cause breast cancer?

Women who report greater use of cleaning products may be at higher breast cancer risk than those who say they use them sparingly. Researchers writing in BioMed Central’s open access journal Environmental Health asked more than 1500 women about their cleaning product usage and found that women who reported using more air fresheners and products for mold and mildew control had a higher incidence of breast cancer.

Julia Brody, from the Silent Spring Institute, USA, worked with a team of researchers to carry out telephone interviews with 787 women diagnosed with breast cancer and 721 comparison women. She said, “Women who reported the highest combined cleaning product use had a doubled risk of breast cancer compared to those with the lowest reported use. Use of air fresheners and products for mold and mildew control were associated with increased risk. To our knowledge, this is the first published report on cleaning product use and risk of breast cancer.”

The researchers questioned women on product use, beliefs about breast cancer causes, and established and suspected risk factors. They found that cleaning products, air fresheners, and insect repellents were associated with breast cancer, but little association was observed with overall pesticide use. Women with breast cancer who believed that chemicals and pollutants contribute ‘a lot’ to the risk of developing the condition were more likely to report high product usage. Speaking about this potential bias to the study, Brody said, “When women are diagnosed with breast cancer, they often think about what happened in the past that might have contributed to the disease. As a result, it may be that women with breast cancer more accurately recall their past product use or even over-estimate it. Or, it could also be that experience with breast cancer influences beliefs about its causes. For example, women diagnosed with breast cancer are less likely to believe heredity contributes ‘a lot’, because most are the first in their family to get the disease.”

In order to avoid possible recall bias, the researchers recommend further study of cleaning products and breast cancer using prospective self-reports and measurements in environmental and biological media.

Public release date: 19-Jul-2010

Painters at significantly increased risk of bladder cancer

Bladder cancer risk in painters: a meta-analysis

Painters are at significantly increased risk of developing bladder cancer, concludes a comprehensive analysis of published evidence in Occupational and Environmental Medicine.

And the risk increases the longer a person works as a professional painter, the analysis shows.

The authors base their findings on almost 3000 cases of bladder cancer arising in professional painters, reported in 41 separate studies.

Other related occupations, such as plasterers, glaziers, wallpaper hangers, artists and decorators were classified as “painters” in some studies.

The International Agency for Research on Cancer (IARC) estimates that bladder cancer is the 9th most common cancer worldwide, with more than 330,000 new cases diagnosed every year and an annual death toll of 130,000.

A key risk factor for the disease is smoking, but higher numbers than expected of bladder cancer have also been reported for certain types of employment, including painting.

Painters are exposed to some of the same chemicals that are found in cigarette smoke, including aromatic amines.

The authors included studies which assessed whether participants were smokers, in a bid to unpick the impact of painters’ occupational exposures on bladder cancer risk.

They found that after taking account of smoking, painters were still 30% more likely to develop bladder cancer than the general population.

This heightened risk persisted when other risk factors were accounted for as well, suggesting that painting is an independent risk factor for the disease.

There was some evidence that female painters were more likely than their male counterparts to develop bladder cancer, but only four studies presented results separately for women.

The researchers say their results are strengthened by the finding that length of employment as a painter had a significant impact on bladder cancer risk.

Those who had worked in this capacity for more than 10 years were more likely to develop bladder cancer than those who had been in this kind of employment for under 10 years.

It is not known which agents are implicated in this heightened risk, say the authors. And the picture is complicated by the variability of the work involved, differing levels of exposure, and the fact that paint composition has changed over time.

But there is now sufficient evidence that painters run an occupational risk of bladder cancer, they conclude. “Because several million people are employed as painters worldwide, even a modest increase in the relative risk is remarkable,” they warn.

Public release date: 19-Jul-2010

UT researchers: English ivy may give sunblock a makeover

 

Nanoparticles in ivy may hold the key to making sunscreen safer and more effective.

When Mingjun Zhang was watching his son play in the yard, he was hit with a burning question: “What makes the ivy in his backyard cling to the fence so tightly?”

That simple question has led to a pioneering discovery that the tiny particles secreted from ivy rootlets can be used in many breakthrough applications in items such as military technologies, medical adhesives and drug delivery, and, most recently, sun-block.

Zhang, an associate professor of biomedical engineering at the University of Tennessee, Knoxville, along with his research team and collaborators, has found that ivy nanoparticles may protect skin from UV radiation at least four times better than the metal-based sunblocks found on store shelves today.

“The discovery of ivy nanoparticles’ application to sunscreen was triggered by a real need. While hearing a talk at a conference about toxicity concerns in the use of metal-based nanoparticles in sunscreen, I was wondering, ‘Why not try naturally occurring organic nanoparticles?'” Zhang said.

Zhang speculated the greenery’s hidden power lay within a yellowish material secreted by the ivy for surface climbing. He placed this material onto a silicon wafer and examined it under an atomic force microscope and was surprised by what they found — lots of nanoparticles, tiny particles 1,000 times thinner than the diameter of a human hair. The properties of these tiny bits create the ability for the vine leaves to hold almost 2 million more times than its weight. It also has the ability to soak up and disperse light which is integral to sunscreens.

“Nanoparticles exhibit unique physical and chemical properties due to large surface-to-volume ratio which allows them to absorb and scatter light,” Zhang said. “Titanium dioxide and zinc oxide are currently used for sunscreen for the same reason, but the ivy nanoparticles are more uniform than the metal-based nanoparticles, and have unique material properties, which may help to enhance the absorption and scattering of light, and serve better as a sun-blocker.”

The team’s study indicates that ivy nanoparticles can improve the extinction of ultraviolet light at least four times better than its metal counterparts. Furthermore, the metal-based sunscreens used today can pose health hazards. Zhang notes some studies have shown that the small-scale metal oxides in sunscreen can wind up in organs such as the liver or brain.

Ivy nanoparticles, on the other hand, exhibit better biocompatibility with humans and the environment. The team’s studies indicate that the ivy nanoparticles were less toxic to mammalian cells, have a limited potential to penetrate through human skin, and are easily biodegradable.

“In general, it is not a good idea to have more metal-based nanoparticles for cosmetic applications. They are a significant concern for the environment. Naturally occurring nanoparticles originated from plants seem to be a better choice, especially since they have been demonstrated to be less toxic and easily biodegradable,” Zhang said.

Sunscreens made with ivy nanoparticles may not need to be reapplied after swimming. That’s because the plant’s nanoparticles are a bit more adhesive so sunscreens made with them may not wash off as easily as traditional sunscreens. And while sunscreens made with metal-based nanoparticles give the skin a white tinge, sunscreens made with ivy nanoparticles are virtually invisible when applied to the skin.

Public release date: 20-Jul-2010

Natural substance NT-020 aids aging brains in rats, USF study finds

Researchers suggest aging may be ‘a stem cell disease’

Tampa, FL (July 20, 2010) – A combination of nutrients called NT-020 promoted adult neural stem cell proliferation in aged rats and boosted their memory performance, reported University of South Florida researchers studying natural therapeutic approaches to promoting the health of neurons in the aging brain.

Researchers from the USF Department of Neurosurgery and Brain Repair tested two groups of aged laboratory rats; one group received NT-020 and another, the control group, did not. In the NT-020 group, the process by which neurons are generated — called neurogenesis — increased.

The NT-020 formula was patented by USF and licensed to Natura Therapeutics, Inc. The study was published in the current issue of Rejuvenation Research (Vol. 13 No. 5, June, 2010).

Aging has been linked to oxidative stress, and we have previously shown that natural compounds made from blueberries, green tea, and amino acids, such as carnosine, are high in antioxidants and have anti-inflammatory and anti-oxidative activity,” said Sandra Acosta, MS, the study’s lead author and a PhD student in the USF Center of Excellence in Aging and Brain Repair . “The combination of these nutrients, called NT-020, creates a synergistic effect that promotes the proliferation of stem cells in the aged animals.”

 

Acosta and colleagues compared the NT-020 group to the control group by evaluating their performance on a variety of behavioral and memory tests, including a spatial navigation test. The NT-020 group demonstrated increased adult neural stem cell proliferation in the two main stem cell niches in the brains and improvement in learning and memory.

In past studies, NT-020 has been shown to have beneficial effects on animals with simulated stroke. NT-020 has also been shown to encourage the proliferation of adult stem cells, which have the potential to develop into tissue and bone cells and also migrate to areas of damage to help with repair.

That increased stem cell proliferation coincided with better cognitive performance is significant.

“The notion that aging is a stem cell disease has been gaining popularity,” said study senior author Paula Bickford, PhD, professor of neurosurgery and brain repair at USF. “Our hypothesis is that aging alters the local environment in the brain and other organs and can promote an environment that retards the growth of stem cells. For example, high glucose, which would be seen with diabetes, excessive alcohol and oxidative stress, can lead to reduced neurogenesis.”

The researchers concluded that increased inflammation in the brains of the aged animals led to reduced production of stem cells, but that stem cell renewal created a rejuvenating effect. They found that NT-020 treated animals had fewer activated inflammatory cells in the brain, reflecting a decrease in factors that reduced the production of stem cells.

 

“NT-020 may have not only a positive effect on the stem cell niche,” concluded Bickford. “NT-020 may have far-reaching effects on organ function beyond the replacement of injured cells, as demonstrated by cognitive improvement in the NT-020 group.”

Public release date: 20-Jul-2010

 

Probiotic use in mothers limits eczema in their babies

(20.07.2010) Mothers who drank milk with a probiotic supplement during and after pregnancy were able to cut the incidence of eczema in their children by almost half, a new study published in the British Journal of Dermatology has shown.

The randomized, double-blind study, conducted by researchers at the Norwegian University of Science and Technology (NTNU), compared mothers who drank one glass of probiotic milk a day to women who were given a placebo. Use of the probiotic milk – which the mothers drank beginning at week 36 in their pregnancy up through to three months after birth — reduced the incidence of eczema by 40 percent in children up to age two, the researchers found. The study is a part of a larger research project at the university called the Prevention of Allergy Among Children in Trondheim, or PACT, an ongoing population-based intervention study in Norway focused on childhood allergy.

Random sample of pregnant women

Researchers followed 415 pregnant women and their children from pregnancy until the children were two years old. The participants were randomly selected among pregnant women in Trondheim – and then randomly divided into two groups, one of which was given milk with probiotics, and the other a placebo milk. Mothers in the study did not know whether they were given the probiotic milk or the placebo milk.

“The taste of both products was similar, and the milk was delivered in unmarked milk cartons. This means that neither the participants in the study or the researchers knew who had received probiotic milk or placebo milk,” says NTNU researcher Torbjørn Øien, one of the scientists involved in the study. “We can therefore say with great certainty that it was the probiotic bacteria alone that caused the difference in the incidence of eczema between the two groups.”

Eczema incidence lower, or less severe

The children were checked for eczema throughout the period, as well as for asthma and allergy at age two. Afterwards, the incidence of asthma, eczema and allergy was compared in the two groups.

“The results showed that probiotic bacteria reduced the incidence of eczema in children up to age two years by 40 percent. And the kids in ‘probiotics group’ who did have eczema, had less severe cases,” explains Christian Kvikne Dotterud, a student in the Medical Student Research Programme at the Department of Community Medicine at NTNU.

The study did not show any effect from the probiotic milk on asthma or allergies, however.

More research on allergic diseases

Dotterud and his research colleagues have started a follow-up study of the children to see if they find any preventive effect on allergic diseases, especially asthma, when children have reached six years old.

“Our study is the first to show that certain probiotic bacteria given to the mother during pregnancy and breast-feeding prevents eczema,” says Dotterud.

Previous studies have shown that ingestion of some probiotics by children may prevent eczema, but this is the first study to show a preventative effect when the mother alone consumed the probiotics.

Via breast milk

“In Norway, there has been some skepticism about giving infants probiotics. Therefore, it is preferable that mothers take probiotics, not children,” he said. Probiotics are generally considered safe for healthy people.

To participate in the study mothers had to have planned to breastfeed their children.

“We believe that probiotic bacteria affects breast milk composition in a positive way,” Dotterud said.

The study was sponsored by Tine SA, which produced and distributed the milk used in the study. Tine SA is s Norway’s largest producer, distributor and exporter of dairy products, and is a cooperative owned by 15,084 Norwegian dairy farmers. Tine SA had no role in the study designs, data collection or data analysis.

The results of the study have been published in the journal The British Journal of Dermatology. The article is entitled: Probiotics in pregnant women to prevent allergic disease: a randomised, double-blind trial [Epub ahead of print]

Why the increase in asthma and allergies in Norway?

PACT, the Prevention of Allergy Among Children in Trondheim study – was started in 2000 as a primary prevention, controlled study to look at measures that might reduce the increase in the incidence of asthma and allergies that has been recorded in Norway in recent decades.

It is an ongoing population-based intervention study in Norway focused on the impacts on childhood allergy of systematic and structure interventions to reduce tobacco exposure, increase the consumption of n-3 polyunsaturated fatty acids, and reduce indoor dampness.

What are probiotics?

Probiotics are live lactic acid bacteria which can be added to food and drink. In contrast to common lactic acid bacteria used in the acidification of products such as milk and yogurt, probiotic bacteria have the ability to survive through the acidic stomach environment and settle temporarily in the intestine. The probiotic lactic acid bacteria have a natural place in the digestive system, where they strengthen normal intestinal flora and are good for the body.

What kind of probiotic milk did the scientists use?

Researchers used the Norwegian product Biola from Tine SA. There are wide variations in terms of how well the strains in the probiotic products on the market have been documented. Biola contains LGG ®, the probiotic bacteria that are currently the most extensively studied in the world. Biola product used in the study also contains Lactobacillus acidophilus (La-5) and Bifidobacterium lactis (Bb-12). These also have documented health effects, albeit less extensive than LGG ®. There is reason to believe that it is beneficial for your health to consume a variety of bacterial strains with documented efficacy, rather than unilateral influence of only one bacterial strain.

What is LGG ®?

LGG ® (Lactobacillus rhamnosus GG) is the probiotic bacteria strain that has been the most studied and researched in terms of human health effects. It has been shown that LGG ® contributes to good gut function and a stronger defense against unwanted bacteria and viruses in the stomach. At present there are more than 500 published articles on LGG ® in international journals and more than 30 doctoral theses have been completed on LGG’s ® effect on health. More than 40 countries in different parts of the world market products with LGG ®.

Public release date: 20-Jul-2010

Asthma and eczema sufferers have a lower risk of developing a cancer

 

Men who had a history of asthma or eczema generally had a lower risk of developing cancer, according to a study carried out by researchers at INRS–Institut Armand-Frappier, the Research Centre of the Centre hospitalier de l’Université de Montréal, and McGill University. The findings, published in the Annals of Allergy, Asthma & Immunology, show that male eczema sufferers had a lower risk of lung cancer while those with a history of asthma had a similar effect in relation to stomach cancer.

“Asthma and eczema are allergies brought about by a hyper-reactive immune system – a state which might have enabled abnormal cells to have been eliminated more efficiently, thereby reducing the risk of cancer,” explained Professor Marie-Claude Rousseau of the INRS–Institut Armand-Frappier, one of the co-authors of the research.

The researchers analyzed information that was collected in a study on exposures in the workplace and the risk of developing cancer, undertaken between August 1979 and March 1986. It involved 3,300 men, between 35 and 70 years of age, who had been diagnosed with cancer in one of Montreal’s 18 hospitals, and a control group of 512 people from the general population who did not have cancer. The researchers used the data from this study to determine if there was a link between allergies such as asthma and eczema and the incidence of eight most common types of cancer.

These findings contribute important knowledge to population health and provide new research leads. Although the study did not allow to identify which specific factors related to asthma and eczema were responsible for reducing the risk of cancer, it offers new angles for research into the molecular and immunological mechanisms that are involved in immunostimulation, a potentially promising strategy for cancer prevention.

Public release date: 21-Jul-2010

Research links recreational pool disinfectants to health problems

 

URBANA – Splashing around in a swimming pool on a hot summer day may not be as safe as you think. A recent University of Illinois study links the application of disinfectants in recreational pools to previously published adverse health outcomes such as asthma and bladder cancer.

Each year, 339 million visits take place at pools and water parks across the United States. Not only is swimming fun, but it’s also the second most popular form of exercise in the country. Because of this, disinfection of recreational pools is critical to prevent outbreaks of infectious disease.

However, Michael Plewa, U of I professor of genetics, said negative outcomes can occur when disinfection byproducts form reactions with organic matter in pool water.

Pool water represents extreme cases of disinfection that differ from the disinfection of drinking water as pools are continuously exposed to disinfectants.

“All sources of water possess organic matter that comes from decaying leaves, microbes and other dead life forms,” Plewa said. “In addition to organic matter and disinfectants, pool waters contain sweat, hair, skin, urine, and consumer products such as cosmetics and sunscreens from swimmers.”

These consumer products are often nitrogen-rich, causing concern that they may contribute to the generation of nitrogenous disinfection byproducts, Plewa added. When mixed with disinfectants, these products may become chemically modified and converted into more toxic agents. These disinfection byproducts can mutate genes, induce birth defects, accelerate the aging process, cause respiratory ailments, and even induce cancer after long-term exposures. In this study, collections from public pools and a control sample of tap water were evaluated to identify recreational water conditions that could be harmful to your health.

A systematic mammalian cell genotoxicity analysis was used to compare the water samples. Plewa said this sensitive DNA technology examined genomic damage in mammalian cells, allowing researchers to investigate damage at the level of each nucleus within each cell.

The study compared different disinfection methods and environmental conditions. Results proved that all disinfected pool samples exhibited more genomic DNA damage than the source tap water, Plewa said.

“Care should be taken in selecting disinfectants to treat recreational pool water,” Plewa advised. “The data suggest that brominating agents should be avoided as disinfectants of recreational pool water. The best method to treat pool waters is a combination of UV treatment with chlorine as compared to chlorination alone.”

Plewa recommends that organic carbon be removed prior to disinfection when the pool water is being recycled.

Also, swimmers can help reduce the genotoxicity of pool water by showering before entering the water. Pool owners should also remind patrons about the potential harm caused by urinating in a pool. These simple steps can greatly reduce the precursors of toxic disinfection byproducts, Plewa said.

Public release date: 21-Jul-2010

New evidence that chili pepper ingredient fights fat

Capsaicin, the stuff that gives chili peppers their kick, may cause weight loss and fight fat buildup by triggering certain beneficial protein changes in the body, according to a new study on the topic. The report, which could lead to new treatments for obesity, appears in ACS’ monthly Journal of Proteome Research.

Jong Won Yun and colleagues point out that obesity is a major public health threat worldwide, linked to diabetes, high blood pressure, heart disease, and other health problems. Laboratory studies have hinted that capsaicin may help fight obesity by decreasing calorie intake, shrinking fat tissue, and lowering fat levels in the blood. Nobody, however, knows exactly how capsaicin might trigger such beneficial effects.

In an effort to find out, the scientists fed high-fat diets with or without capsaicin to lab rats used to study obesity. The capsaicin-treated rats lost 8 percent of their body weight and showed changes in levels of at least 20 key proteins found in fat. The altered proteins work to break down fats. “These changes provide valuable new molecular insights into the mechanism of the antiobesity effects of capsaicin,” the scientists say.

Public release date: 22-Jul-2010

Could diabetes be in your bones?

Our bones have much greater influence on the rest of our bodies than they are often given credit for, according to two new studies in the July 23 issue of Cell, a Cell Press publication. Both studies offer new insights into the interplay between bone and blood sugar, based on signals sent via insulin and a bone-derived hormone known as osteocalcin.

Mice whose bones can’t respond to insulin develop high blood sugar and insulin resistance, both hallmarks of diabetes. Those symptoms are tied to a drop in osteocalcin. The findings suggest that osteocalcin, or perhaps a drug that targets bone, might hold promise in fighting the global epidemic of type 2 diabetes, according to the researchers.

“Our study reveals a key molecular link between bone remodeling and metabolism,” said Gerard Karsenty of Columbia University.

“Bone is an organ that has to pay attention to where calories are going,” added Thomas Clemens of Johns Hopkins University School of Medicine. “It talks to muscle, fat, the pancreas. It’s a player in energy metabolism.”

And perhaps that makes a lot of sense, Karsenty said. The remodeling of bone relies on two cell types, bone-building osteoblasts and bone-resorbing osteoclasts, making bone the only organ with a cell type that is entirely focused on destroying host tissue. “On a daily basis, the formation of bone is expensive in terms of energy,” he said.

In fact, the idea that the skeleton is much more than a reservoir for calcium and phosphate isn’t entirely new, the researchers said. Earlier evidence by Karsenty’s group had shown links between bone and the fat hormone leptin. (Obese adults are significantly less likely to develop osteoporosis.)

Scientists also had evidence that osteoblasts might respond to insulin in important ways. Osteoblasts bear insulin receptors and when treated with insulin show signs of collagen synthesis and take up more glucose, Clemens’ team notes. People with type 1 diabetes due to a lack of insulin can also develop weakened bones.

Karsenty’s team describes bone as a multitasker. It has mechanical, hematopoietic (blood-producing) and metabolic functions. It also acts as an endocrine organ through the release of osteocalcin hormone, which favors glucose metabolism when in its active form.

Still, Clemens said he was surprised by what they saw after developing a mouse lacking insulin receptors only in their osteoblasts. “The mice started to get fat,” he said. They showed changes in their biochemistry that were consistent with insulin resistance. They also had low osteocalcin levels and fewer osteoblasts to produce less bone.

With age, the animals became even fatter and developed more marked high blood sugar accompanied by severe glucose intolerance and insulin resistance. Those symptoms improved with osteocalcin treatment.

Karsenty’s group presents independent evidence for the important role of insulin in bone for keeping glucose in check through osteocalcin, in what he refers to as a “feed-forward loop.” But his group goes a step further to suggest that bone-resorbing osteoclasts (not just osteoblasts) have a place in this too.

Karsenty explains that bone-building osteoblasts actually control bone resorption by osteoclasts, a process that takes place under very acidic conditions. Those conditions would also favor the chemical modification necessary to produce active osteocalcin, which can escape bone to act as a hormone.

That could be important to those who take osteoporosis drugs designed to block bone resorption, Karsenty suggests. “It’s a red flag,” he said. “Osteoporotic patients treated with [bone resorption inhibitors] may be at risk of glucose intolerance.”

Public release date: 22-Jul-2010

Vitamins needed to help celiacs stave off bone disease

Children with celiac disease need to include certain must-have vitamins in their diets to stave off weak bones and osteoporosis, say researchers at the University of Alberta.

A study of 43 children and teens from three to 18 years of age diagnosed with celiac disease showed that they also tended to have low bone density, likely due to poor intake and absorption of vitamins and minerals. That means they should be getting more of bone-boosting vitamins such as K and D in their diets, says Diana Mager, a professor of agricultural, food and nutritional science at the U of A, and one of the researchers on the project.

“Children with celiac disease are at risk for poor bone health, but by adding vitamins K and D to their diets, it can help reduce the risk of fractures and osteoporosis,” Mager said.

The study revealed that the children were getting less than 50 per cent of their recommended dietary intake of Vitamin K, and that they also suffered from low levels of Vitamin D, which can be raised through increased exposure to sunlight and by eating fortified dairy products.

Mager also recommends that children with celiac disease include physical activity in their daily routines to build their bone strength and boost their Vitamin D intake by exercising outside.

“Enjoying activities such as walking and running outdoors when there is more sunshine is a great way to contribute to healthy bones,” Mager said

Public release date: 25-Jul-2010

Non-human sugar in biotech drugs causes inflammation

Researchers at the University of California, San Diego School of Medicine have discovered that a kind of sugar molecule common to chimpanzees, gorillas and other mammals but not found in humans provokes a strong immune response in some people, likely worsening conditions in which chronic inflammation is a major issue.

This non-human sialic acid sugar is an ingredient in some biotechnology drugs, and may be limiting or undermining their therapeutic effectiveness in some patients, the scientists report in a letter published in the advance online July 25 edition of the journal Nature Biotechnology. However, they also propose a simple modification to the drug-making process that could solve the problem.

The presence of the non-human sialic acid sugar contaminant, called N-glycolyneuraminic acid or Neu5Gc, has long been known but ignored because it was believed healthy human immune systems did not react to it, said Ajit Varki, MD, professor of medicine and cellular and molecular medicine at UC San Diego School of Medicine. “Now we know that to be untrue.” “We’re all exposed to this non-human sugar,” Varki added. “It’s part of our diet, and especially abundant in red meat. We all develop antibodies to Neu5Gc, but this immune response varies greatly in people. Meanwhile, Neu5Gc from animal foods can get incorporated into the human body. For most people, this may not be a problem. But for some, the immune response to incorporated Neu5Gc may exacerbate a chronic inflammation process. This isn’t the cause of any disease or condition, but we believe it might be akin to adding fuel to an existing fire.”

Every animal cell is cloaked in sugar molecules, which serve as vital contact points for interaction with other cells and their surrounding environment. At the same time, the attached sugars are targets for infectious diseases like influenza, malaria and cholera.

“Sialic acids are required for survival, but they’re also used to attack you,” said Varki, who is founder and co-director of the Glycobiology Research and Training Center at UC San Diego. “They are crucial for things like brain plasticity and kidney function, but lots of pathogens attach to them, and some even coat themselves with these sugars to avoid detection. In evolutionary terms, if you have sialic acid, you’re going to be attacked. But you don’t have it, you’re going to die.”

Perhaps because of this evolutionary pressure, different species can have different kinds of sialic acids. In mammals, there are two major types: Neu5Gc and Neu5Ac, which differ by one oxygen atom. Humans have only the “Ac” version; other mammals also have the “Gc” version. This human-specific change likely happened two or three million years ago, said Varki, who also co-directs the Center for Academic Research Training in Anthropogeny at UCSD. “No one knows why, but this may have been selected by an infectious disease, like malaria”

Although the Ac and Gc versions are very similar in structure, the single oxygen atom difference is recognized by the human immune system, which develops antibodies to the non-human sugar.

And therein lies the problem, said Varki. Antibodies are naturally circulating proteins that identify and neutralize invaders, such as viruses or bacteria. Part of that process involves inflammation, the host’s attempt to kill and remove invasive cells or tissues perceived to be harmful. If there is a strong antibody response to diet-incorporated Neu5Gc, the resulting inflammation could cause harm to the person. This may partially explain associations between certain foods and increased risk of diseases associated with inflammation, such as cancer and heart attacks – diseases that are rare in other primates.

The problem may also be exacerbated by the presence of Neu5Gc in drugs developed through recombinant biotechnology, some of which are actually used to treat inflammatory disorders. Neu5Gc contamination is unavoidable with current methods, said Varki, because many biotherapeutics such as antibodies, clotting factors or hormones are produced using cells, tissues or serum from mammalian sources, which naturally contain the non-human sialic acid.

Varki and colleagues studied several biotherapeutic agents currently in clinical use, and found the non-human sialic acid in almost all of them, although in varying amounts.

They also report that anti-Neu5Gc antibodies from normal humans interacted with a Neu5Gc-containing drug used to treat some forms of cancer, producing immune complexes in vitro. Mice with a human-like defect in Neu5Gc synthesis also generated anti-Neu5Gc antibodies when injected with the drug, and cleared it from the circulation faster.

These problems were not seen with another otherwise similar drug, which happened to be practically free of Neu5Gc.

“It’s reasonable to suggest that for some patients who have problems with some drugs, this may be part of the reason why,” although a lot more needs to be done to work out the details,” Varki said.

Meanwhile, the UCSD scientists have developed a novel yet simple solution: Add the human sialic acid to the drug-making process. The Ac version, said Varki, competes with the Gc version, reducing the chances of the Gc version making it into the final product.

 

“In our initial tests, it removes low-level Gc contamination in drugs,” said Varki. “It’s simple and should only require minor FDA approval for the process adjustment. We think that while we’ve identified a problem, we’ve also come up with an answer, at least for some drugs.”

Public release date: 27-Jul-2010

Alcohol reduces the severity of rheumatoid arthritis

Drinking alcohol may reduce the severity of rheumatoid arthritis according to new research published today. It is the first time that this effect has been shown in humans. The study also finds that alcohol consumption reduces the risk of developing the disease, confirming the results of previous studies.

The study which is published online today in the journal Rheumatology (Wednesday 28 July), looked at 873 patients with rheumatoid arthritis and compared them with 1004 people without RA (the control group). The researchers, led by Gerry Wilson, Professor of Rheumatology at the University of Sheffield (Sheffield, UK), asked the two groups how frequently they had drunk alcohol in the month preceding their inclusion in the study. The study participants completed a detailed questionnaire, had x-rays and blood tests, and an experienced research nurse examined their joints.

The first author of the study, Dr James Maxwell, a consultant rheumatologist at the Rotherham Foundation NHS Trust and an honorary senior clinical lecturer in the Academic Rheumatology Group at the University of Sheffield, said: “We found that patients who had drunk alcohol most frequently had symptoms that were less severe than those who had never drunk alcohol or only drunk it infrequently. X-rays showed there was less damage to joints, blood tests showed lower levels of inflammation, and there was less joint pain, swelling and disability. This is the first time that a dose dependent inverse association between frequency of alcohol consumption and severity of RA has been shown in humans.”

Dr Maxwell and his colleagues also found that non-drinkers were four times more likely to develop RA than people who drank alcohol on more than ten days a month. The risk of developing RA decreased according to the frequency of alcohol consumption. “This finding agrees with the results from previous studies that have shown a decreased susceptibility to developing RA among alcohol drinkers,” said Dr Maxwell.

The researchers found that their findings applied regardless of gender and in both the anti cyclic citrullinated peptide (CCP) positive and negative forms of RA. “Anti-CCP antibodies are not present in most ‘normal’ people without arthritis,” explained Dr Maxwell. “We know that these antibodies develop prior to the onset of RA, and are probably directly linked to the process which causes RA. Some patients have RA without having anti-CCP antibodies, but we know that the disease is much more severe in patients who do.”

It is not fully understood why drinking alcohol should reduce the severity of RA and people’s susceptibility to developing it. “There is some evidence to show that alcohol suppresses the activity of the immune system, and that this may influence the pathways by which RA develops. We do know that the changes in the immune system that lead to RA happen months and maybe even years before the arthritis actually develops,” said Dr Maxwell. “Once someone has developed RA, it’s possible that the anti-inflammatory and analgesic effects of alcohol may play a role in reducing the severity of symptoms.

“Further research is needed to confirm the results of our study and to investigate the mechanisms by which alcohol influences people’s susceptibility to RA and the severity of symptoms. It is also possible that different types of alcoholic drinks may have different effects on RA.”

The authors point out that there are some limitations to their study. These include the fact that they only recorded the frequency rather than the amount of alcohol consumption in the month before people joined the study; there might be bias due to people recalling inaccurately how often they drank alcohol and also the information represents a snapshot of drinking behaviour at one point in time, rather than giving information about fluctuating alcohol consumption over a longer period; and, finally, there were marked differences in age and gender between the RA and the control groups, although the researchers did adjust their results for these factors.

Writing in their paper, the study authors conclude: “While there are a number of limitations to the methodology of this study, the results do suggest that the consumption of alcohol may modify RA, influencing both risk and severity.”

Public Release: 29-Jul-2010

 

Western diet link to ADHD

A new study from Perth’s Telethon Institute for Child Health Research shows an association between ADHD and a ‘Western-style’ diet in adolescents.

The research findings have just been published online in the international Journal of Attention Disorders.

Leader of Nutrition studies at the Institute, Associate Professor Wendy Oddy, said the study examined the dietary patterns of 1800 adolescents from the long-term Raine Study and classified diets into ‘Healthy’ or ‘Western’ patterns.

“We found a diet high in the Western pattern of foods was associated with more than double the risk of having an ADHD diagnosis compared with a diet low in the Western pattern, after adjusting for numerous other social and family influences,” Dr Oddy said.

“We looked at the dietary patterns amongst the adolescents and compared the diet information against whether or not the adolescent had received a diagnosis of ADHD by the age of 14 years.  In our study, 115 adolescents had been diagnosed with ADHD, 91 boys and 24 girls.”

A “healthy” pattern is a diet high in fresh fruit and vegetables, whole grains and fish. It tends to be higher in omega-3 fatty acids, folate and fibre. A “Western” pattern is a diet with a trend towards takeaway foods, confectionary, processed, fried and refined foods. These diets tend to be higher in total fat, saturated fat, refined sugar and sodium.

“When we looked at specific foods, having an ADHD diagnosis was associated with a diet high in takeaway foods, processed meats, red meat, high fat dairy products and confectionary,” Dr Oddy said.

“We suggest that a Western dietary pattern may indicate the adolescent has a less optimal fatty acid profile, whereas a diet higher in omega-3 fatty acids is thought to hold benefits for mental health and optimal brain function.

“It also may be that the Western dietary pattern doesn’t provide enough essential micronutrients that are needed for brain function, particularly attention and concentration, or that a Western diet might contain more colours, flavours and additives that have been linked to an increase in ADHD symptoms. It may also be that impulsivity, which is a characteristic of ADHD, leads to poor dietary choices such as quick snacks when hungry.”

Dr Oddy said that whilst this study suggests that diet may be implicated in ADHD, more research is needed to determine the nature of the relationship.

“This is a cross-sectional study so we cannot be sure whether a poor diet leads to ADHD or whether ADHD leads to poor dietary choices and cravings,” Dr Oddy said.

ADHD is the most commonly diagnosed childhood mental health disorder and has a prevalence of approximately 5%.  ADHD is known to be more common in boys

Plant Compound Resveratrol Shown to Suppress Inflammation, Free Radicals, in Humans

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Public Release: 29-Jul-2010

Research by UB’s Paresh Dandona and colleagues points to the anti-inflammatory effects of the plant compound resveratrol.

BUFFALO, N.Y. — Resveratrol, a popular plant extract shown to prolong life in yeast and lower animals due to its anti-inflammatory and antioxidant properties, appears also to suppress inflammation in humans, based on results from the first prospective human trial of the extract conducted by University at Buffalo endocrinologists.

Results of the study appear as a rapid electronic publication on the Journal of Clinical Endocrinology & Metabolism website and will be published in an upcoming print issue of the journal.

The paper also has been selected for inclusion in Translational Research in Endocrinology & Metabolism, a new online anthology that highlights the latest clinical applications of cutting-edge research from the journals of the Endocrine Society.

Resveratrol is a compound produced naturally by several plants when under attack by pathogens such as bacteria or fungi, and is found in the skin of red grapes and red wine. It also is produced by chemical synthesis derived primarily from Japanese knotweed and is sold as a nutritional supplement.

Husam Ghanim, PhD, UB research assistant professor of medicine and first author on the study, notes that resveratrol has been shown to prolong life and to reduce the rate of aging in yeast, roundworms and fruit flies, actions thought to be affected by increased expression of a particular gene associated with longevity.

The compound also is thought to play a role in insulin resistance as well, a condition related to oxidative stress, which has a significant detrimental effect on overall health.

“Since there are no data demonstrating the effect of resveratrol on oxidative and inflammatory stress in humans,” says Paresh Dandona, MD, PhD, UB distinguished professor of medicine and senior author on the study, “we decided to determine if the compound reduces the level of oxidative and inflammatory stress in humans.

“Several of the key mediators of insulin resistance also are pro-inflammatory, so we investigated the effect of resveratrol on their expression as well.”

The study was conducted at Kaleida Health’s Diabetes-Endocrinology Center of Western New York, which Dandona directs.

A nutritional supplement containing 40 milligrams of resveratrol was used as the active product. Twenty participants were randomized into two groups of 10: one group received the supplement, while the other group received an identical pill containing no active ingredient. Participants took the pill once a day for six weeks. Fasting blood samples were collected as the start of the trial and at weeks one, three and six.

Results showed that resveratrol suppressed the generation of free radicals, or reactive oxygen species, unstable molecules known to cause oxidative stress and release proinflammatory factors into the blood stream, resulting in damage to the blood vessel lining.

Blood samples from persons taking resveratrol also showed suppression of the inflammatory protein tumor necrosis factor (TNF) and other similar compounds that increase inflammation in blood vessels and interfere with insulin action, causing insulin resistance and the risk of developing diabetes.

These inflammatory factors, in the long term, have an impact on the development of type 2 diabetes, aging, heart disease and stroke, noted Dandona.

Blood samples from the participants who received the placebo showed no change in these pro-inflammatory markers.

While these results are promising, Dandona added a caveat: The study didn’t eliminate the possibility that something in the extract other than resveratrol was responsible for the anti-inflammatory effects.

“The product we used has only 20 percent resveratrol, so it is possible that something else in the preparation is responsible for the positive effects. These agents could be even more potent than resveratrol. Purer preparations now are available and we intend to test those.”

Additional contributors to the study, all from Dandona’s laboratory, are Chang Ling Sia, Sanaa Abuaysheh, Kelly Korzeniewski, Priyanka Patniak, MD, Anuritha Marumganti, MD, and Ajay Chaudhuri, MD.

The study was supported in part by grants to Dandona from the National Institutes of Health and the American Diabetes Association.

The University at Buffalo is a premier research-intensive public university, a flagship institution in the State University of New York system and its largest and most comprehensive campus. The School of Dental Medicine is one of five schools that constitute UB’s Academic Health Center. UB’s more than 28,000 students pursue their academic interests through more than 300 undergraduate, graduate and professional degree programs. Founded in 1846, the University at Buffalo is a member of the Association of American Universities.

________________________________

 

These reports are done with the appreciation of all the Doctors, Scientist, and other

Medical Researchers who sacrificed their time and effort. In order to give people the

ability to empower themselves. Without the base aspirations for fame, or fortune.

Just honorable people, doing honorable things.

69th Health Research Report 10 NOV 2009 – Reconstruction

 

 

Editors Top Five:

1. Scientists discover influenza’s Achilles heel: Antioxidants

2. Commentary warns of unexpected consequences of (antacid) proton pump inhibitor use in reflux disease

3. First national zinc campaign for childhood diarrhea increases awareness, but use lags behind

4. Mortality Rates Reduced among Children Whose Mothers Received Iron-folic Acid Supplements

5. Acetaminophen may be linked to asthma in children and adults

In this issue:

1. Why fish oils help and how they could help even more

2. Statins show dramatic drug and cell dependent effects in the brain

3. Attention-Deficit/Hyperactivity Problems Associated with Low Folate Levels in Pregnant Women

4. Mortality Rates Reduced among Children Whose Mothers Received Iron-folic Acid Supplements

5. Exercise Keeps Dangerous Visceral Fat Away a Year After Weight Loss, Finds UAB Study

6. High fructose corn syrup: A recipe for hypertension

7. Low vitamin D levels explains most ESRD risk in African-Americans

8. Scientists discover influenza’s Achilles heel: Antioxidants

9. Pregnant women risk early delivery from using psychiatric medication

10. Commentary warns of unexpected consequences of proton pump inhibitor use in reflux disease

11. First national zinc campaign for childhood diarrhea increases awareness, but use lags behind

12. Study examines associations between antibiotic use during pregnancy and birth defects

13. Statins may worsen symptoms in some cardiac patients

14. Children who often drink full-fat milk weigh less

15. Does green tea prevent cancer? Evidence continues to brew, but questions remain

16. Acetaminophen may be linked to asthma in children and adults

17. Researchers explore new ways to prevent spinal cord damage using a vitamin B3 precursor

18. Antimicrobials: Silver (and copper) bullets to kill bacteria

19. People with less education could be more susceptible to the flu


Health Research Report

69th  Issue Date 10 NOV 2009

Compiled By Ralph Turchiano

www.healthresearchreport.me www.vit.bz

www.youtube.com/vhfilm www.facebook.com/engineeringevil

www.engineeringevil.com

 

 

67th Health Research Report 13 OCT 2009 – Reconstruction

Editors Top Five:

1. Aspirin Misuse May Have Made 1918 Flu Pandemic Worse

2. Can strep throat cause OCD, Tourette syndrome?

3. Unnatural selection: Birth control pills may alter choice of partners

4. Where’s the Science? The Sorry State of Psychotherapy

5. Oxidized form of a common vitamin may bring relief for ulcerative colitis

In this Issue:

1. Obesity in middle-aged women cuts chance of a long and healthy life by almost 80 percent

2. Can strep throat cause OCD, Tourette syndrome?

3. Antidepressant and placebo are equally effective in child pain relief

4. Over 65s should take high dose vitamin D to prevent falls, say researchers

5. Oxidized form of a common vitamin may bring relief for ulcerative colitis

6. LSUHSC RESEARCH SHOWS FISH OIL MAY PROTECT AGAINST STROKE FROM RUPTURED CAROTID ARTERY PLAQUES

7. Aspirin Misuse May Have Made 1918 Flu Pandemic Worse

8. Where’s the Science? The Sorry State of Psychotherapy

9. Curcumin may inhibit nicotine-induced activation of head and neck cancers

10. Higher folates, not antioxidants, can reduce hearing loss risk in men

11. Antidepressant use during pregnancy associated with some adverse outcomes in newborns

12. Bell’s palsy: Study calls for rethink of cause and treatment

13. Future diabetes treatment may use resveratrol to target the brain

14. Eating liquorice in pregnancy may affect a child’s IQ and behavior

15. Unnatural selection: Birth control pills may alter choice of partners

16. Women with breast cancer have low vitamin D levels

17. No such thing as ‘junk RNA,’ say Pitt researchers

Health Research Report

67th  Issue Date 13 OCT 2009

Compiled By Ralph Turchiano

www.healthresearchreport.me www.vit.bz

www.youtube.com/vhfilm www.facebook.com/engineeringevil

www.engineeringevil.com

65th Health Resarch Report 15 SEP 2009 – Reconstruction

Editors Top Five:

1. 75 percent would consider letting an unsupervised trainee perform surgery if it could be done quicker

2. Vitamin C deficiency impairs early brain development –

3. Study reveals new role of vitamin C in skin protection

4. ‘Dung of the devil’ plant roots point to new swine flu drugs

5. Popular stomach acid reducer triples risk of developing pneumonia

In this issue:

1. Biotransformed blueberry juice fights fat and diabetes

2. Exercise Minimizes Weight Regain By Reducing Appetite, Burning Fat,

3. And Lowering ‘Defended’ Body Weight

4. Vitamin C deficiency impairs early brain development –

5. UAB Researchers Find Possible Use for Kudzu, the Vine That Ate the South

6. Was the public health response to swine flu alarmist?

7. People with type 2 diabetes not meeting important nutritional recommendations

8. Anticancer compound found in American may apple

9. How manuka honey helps fight infection

10. Houseplants cut indoor ozone

11. High fruit and vegetable intake positively correlated with antioxidant status, cognitive performance

12. 75 percent would consider letting an unsupervised trainee perform surgery if it could be done quicker

13. Study reveals new role of vitamin C in skin protection

14. Regular aerobic exercise reduces health concerns associated with fatty liver

15. ‘Dung of the devil’ plant roots point to new swine flu drugs

16. On-the-job pesticide exposure associated with Parkinson’s disease

17. Antioxidant ingredient proven to relieve stress (S.O.D.)

18. Green tea component may help preserve stored platelets, tissues

19. Popular stomach acid reducer triples risk of developing pneumonia

20. Study Shows Common Pain Cream Could Protect Heart During Attack

21. Supplementing babies’ formula with DHA boosts cognitive development

22. Swine flu vaccination: A test subject speaks out.

Health Research Report

65th  Issue Date 15 SEP 2009

Compiled By Ralph Turchiano

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62nd Health Research Report 04 AUG 2009 – Reconstruction

 

Editors top 5:

  1. Common household pesticides linked to childhood cancer cases in Washington area
  2.  Got zinc? New zinc research suggests novel therapeutic targets
  3.  Study Links Virus To Some Cases Of Common Skin Cancer
  4.  Millions of US children low in vitamin D- (70%)
  5.  Food additive may one day help control blood lipids and reduce disease risk

In this issue:

1. The ‘see food’ diet

2. Almost 1/4 of Spanish women take antidepressants

3. New research finds that bingeing increases opioids in brain area that controls food intake

4. Common food dye may hold promise in treating spinal cord injury

5. Common household pesticides linked to childhood cancer cases in Washington area

6. Got zinc? New zinc research suggests novel therapeutic targets

7. Scientists uncork a potential secret of red wine’s health benefits

8. SAMe is Effective in Preventing Formation of Primary Liver Cancer in Rats

9. Study Links Virus To Some Cases Of Common Skin Cancer

10. Millions of US children low in vitamin D- (70%)

11. Food additive may one day help control blood lipids and reduce disease risk

12. US Marshals seize (anti-bacterial) sanitizer for bacteria problems

13. Antidepressant Use in U.S. Has Almost Doubled

Health Research Report

62nd  Issue Date 04 AUG 2009

Compiled By Ralph Turchiano

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60th Health Research Report 07 JUL 2009 – Reconstruction

Editors Top Five:

1.Your Arteries on Wonder Bread

2.Report: Prostate cancer screening has yet to prove its worth

3. Doubts cast on credibility of some published clinical trials

4. Health food supplement may curb compulsive hair pulling

5. Acid-reducing medicines may lead to dependency

In this issue:

1.Irritability should be considered when diagnosing bipolar disorder in children

2. Kidney damage from medical imaging procedures can cause long-term health problems

3. Chemicals in common consumer products may play a role in pre-term births

4. Vitamin A derivative provides clues to better breast cancer drugs

5.Your Arteries on Wonder Bread

6. Tryptophan deficiency may underlie quinine side effects

7. Mice run faster on high-grade oil

8.Report: Prostate cancer screening has yet to prove its worth

9. Magic ingredient in breast milk protects babies’ intestines

10.K-STATE RESEARCHER STUDIES THE ANTI-CANCER CAPABILITIES OF A SPECIAL PURPLE SWEET POTATO

11.Triggering muscle development — a therapeutic cure for muscle wastage?

12.Acid-reducing medicines may lead to dependency

13.Doubts cast on credibility of some published clinical trials

14.. Caffeine reverses memory impairment in Alzheimer’s mice

15.Researchers find possible environmental causes for Alzheimer’s, diabetes

16.Muscle damage may be present in some patients taking statins

17. Health food supplement may curb compulsive hair pulling

18.Sugar substitute appears to prevent early childhood cavities

Health Research Report

60th Issue Date 07 JUL 2009

Compiled By Ralph Turchiano

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58th Health Research Report 09 JUN 2009 – Reconstruction

 

Editors Top Five:

 

1. Recycled radioactive metal contaminates consumer products

2. Illness, medical bills linked to nearly two-thirds of bankruptcies: Harvard study

3. Bird flu virus remains infectious up to 600 days in municipal landfills

4. How many scientists fabricate and falsify research?

5. Wet ear wax and unpleasant body odors signal breast cancer risk

In this Issue:

1. Use of acid-suppressive medications associated with increased risk of hospital-acquired pneumonia

2. Cancer drug causes patient to lose fingerprints and be detained by US immigration

3. Green tea extract shows promise in leukemia trials

4. History of hyperactivity off-base, says researcher

5. How many scientists fabricate and falsify research?

6. Omega fatty acid balance can alter immunity and gene expression

7. Bird flu virus remains infectious up to 600 days in municipal landfills

8. Silver nanoparticles show “immense potential” in prevention of blood clots

9. Wet ear wax and unpleasant body odors signal breast cancer risk

10. Commonly used medications may produce cognitive impairment in older adults

11. Why dishing does you good: U-M study

12. Sedatives may increase suicide risk in older patients

13. Illness, medical bills linked to nearly two-thirds of bankruptcies: Harvard study

14. Association Found Between Parkinson’s Disease and Pesticide Exposure in French Farm Workers

15. Multivitamins in pregnancy reduce risk of low birth weights

16. Stopping diabetes damage with vitamin C

17. Recycled radioactive metal contaminates consumer products

Health Research Report

58th Issue Date 09 JUN 2009

Compiled By Ralph Turchiano

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140th Health Research Report 19 OCT 2012

 

Editors Top Five:

  1. CAFFEINE MAY BLOCK INFLAMMATION LINKED TO MILD COGNITIVE IMPAIRMENT
  2. MINUTES OF HARD EXERCISE CAN LEAD TO ALL-DAY CALORIE BURN
  3. PREBIOTIC MAY HELP PATIENTS WITH INTESTINAL FAILURE GROW NEW AND BETTER GUT
  4. LINK BETWEEN CREATIVITY AND MENTAL ILLNESS CONFIRMED
  5. LEAVES OF CAROB TREE, SOURCE OF CHOCOLATE SUBSTITUTE, FIGHT FOOD-POISONING BACTERIA: LISTERIA

In This Issue:

  1. PRENATAL MERCURY EXPOSURE MAY BE ASSOCIATED WITH RISK OF ADHD-RELATED BEHAVIORS
  2. CAFFEINE MAY BLOCK INFLAMMATION LINKED TO MILD COGNITIVE IMPAIRMENT
  3. COFFEE SPEEDS UP RETURN OF BOWEL FUNCTION AFTER COLON SURGERY
  4. CHRONIC KIDNEY DISEASE ALTERS INTESTINAL MICROBIAL FLORA, UCI STUDY FINDS
  5. MOUNT SINAI SCHOOL OF MEDICINE STUDY SHOWS VITAMIN C PREVENTS BONE LOSS IN ANIMAL MODELS
  6. RESEARCHERS DISCOVER HOW THE BODY USES VITAMIN B TO RECOGNIZE BACTERIAL INFECTION
  7. STUDY: PARENTING MORE IMPORTANT THAN SCHOOLS TO ACADEMIC ACHIEVEMENT
  8. SURVEY SHOWS SUPPLEMENT USERS HAVE STRONG INTEREST IN NATURAL SOLUTIONS TO MANAGE THEIR CHOLESTEROL
  9. EXERCISE COULD FORTIFY IMMUNE SYSTEM AGAINST FUTURE CANCERS
  10. MINUTES OF HARD EXERCISE CAN LEAD TO ALL-DAY CALORIE BURN
  11. SCIENCE REVEALS THE POWER OF A HANDSHAKE
  12. PREBIOTIC MAY HELP PATIENTS WITH INTESTINAL FAILURE GROW NEW AND BETTER GUT
  13. COCHRANE REVIEW FINDS NO BENEFIT FROM ROUTINE HEALTH CHECKS
  14. VITAMIN D SUPPLEMENTS MAY BENEFIT LUPUS PATIENTS
  15. LINK BETWEEN CREATIVITY AND MENTAL ILLNESS CONFIRMED
  16. MOTHER’S TOUCH COULD CHANGE EFFECTS OF PRENATAL STRESS
  17. EXERCISE MAY LEAD TO BETTER SCHOOL PERFORMANCE FOR KIDS WITH ADHD
  18. OBESE TEEN BOYS HAVE UP TO 50 PERCENT LESS TESTOSTERONE THAN LEAN BOYS, UB STUDY FINDS
  19. IMMUNE RESPONSE MAY LINK SOCIAL REJECTION TO LATER HEALTH OUTCOMES
  20. ANTIDEPRESSANTS LINKED TO INCREASED RISK OF STROKE
  21. 2 COMPONENTS OF RED MEAT COMBINED WITH ALTERATION IN DNA REPAIR INCREASE RISK FOR BLADDER CANCER
  22. DAILY MULTIVITAMINS REDUCE RISK OF CANCER IN MEN
  23. LEAVES OF CAROB TREE, SOURCE OF CHOCOLATE SUBSTITUTE, FIGHT FOOD-POISONING BACTERIA: LISTERIA
  24. LOW CALCIUM DIET LINKED TO HIGHER RISK OF HORMONE CONDITION IN WOMEN

Health Research Report

140th Issue Date 19 OCT 2012

Compiled By Ralph Turchiano

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www.engineeringevil.com

56th Health Research Report 12 MAY 2009 – Reconstruction

 

Editors Top Five:

 

1. Hopkins Children’s study: Folic acid may help treat allergies, asthma

 

2. Research finds Kava safe and effective

 

3. Stronger backbone: DHEA hormone replacement increases bone density in older women

 

4. Why Antidepressants Don’t Live Up to the Hype

 

5. Chinese workers urged to puff up economy by smoking

 

In this issue:

 

1. M. D. Anderson study predicts dramatic growth in cancer rates among US elderly, minorities

 

2. Half a glass of wine a day may boost life expectancy by 5 years

 

3. Hopkins Children’s study: Folic acid may help treat allergies, asthma

 

4. White tea — the solution to the obesity epidemic?

 

5. Drugs to combat anemia in cancer patients increase risk of death

 

6. Low vitamin D causes problems for acutely ill patients

 

7. Popular diabetes treatment could trigger pancreatitis, pancreatic cancer

 

8. Stinky” drywall imported from China raises health and safety concerns

 

9. Chinese workers urged to puff up economy by smoking

 

10. Research finds Kava safe and effective

 

11. Study reveals conflict between doctors, midwives over homebirth

 

12. Stronger backbone: DHEA hormone replacement increases bone density in older women

 

13. Probiotics may help ward off postpartum obesity

 

14. Why Antidepressants Don’t Live Up to the Hype

 

Health Research Report

56th Issue Date 12 MAY 2009

Compiled By Ralph Turchiano

www.healthresearchreport.me www.vit.bz

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www.engineeringevil.com

 

 

55th Health Research Report 28 APR 2009 – Reconstruction

 

 

 

Editors Top Five: (not enough this week to justify)

 

In This Issue:

1.  Could senna improve the quality of colonoscopy preparation with magnesium citrate?

2. Oral Contraceptives Impair Muscle Gains In Young Women

3. New human study reinforces antioxidant benefits of tart cherries

4. An herbal extract inhibits the development of pancreatic cancer

5. Human lung tumors destroy anti-cancer hormone vitamin D, Pitt researchers find

6. Too much sugar is bad, but which sugar is worse: Fructose or glucose?

7. Charred meat may increase risk of pancreatic cancer

8. Vitamin D levels linked to asthma severity

9. Type of vitamin B1 could treat common cause of blindness

10. Long-term complications of melamine consumption in children

11. Drinking diet soda may reduce the risk of forming kidney stones

12. Whiter laundry and a surprising new treatment for kids’ eczema

13. Are we cherry picking participants for studies of antidepressants?

 

 

Health Research Report

55th Issue Date28 APR 2009

Compiled By Ralph Turchiano

www.healthresearchreport.me www.vit.bz

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www.engineeringevil.com

 

54th Health Research Report 14 APR 2009 – Reconstruction

Editors Top Five:

1. The new ‘epigenetics:’ Poor nutrition in the womb causes permanent genetic changes in the offspring

2. Einstein scientists propose new theory of autism

3.Soybean component reduces menopause effects

4. Omega-3 kills cancer cells

5.Aspirin and similar drugs may be associated with brain microbleeds in older adults

In this Issue:

1.Physical activity may strengthen children’s ability to pay attention

2. How probiotics can prevent disease

3. Omega-3 kills cancer cells

4. Source of major health benefits in olive oil revealed

5. Einstein scientists propose new theory of autism

6. Broccoli sprouts may prevent stomach cancer by defeating Helicobacter pylori

7. Biology of flushing could renew niacin as cholesterol drug

8. Oral contraceptives associated with increased risk of lupus

9. Soybean component reduces menopause effects

10.Vitamin D Deficiency Related to Increased Inflammation in Healthy Women, MU Study Finds

11.Parkinson’s disease medication triggers destructive behaviors

12.Aspirin and similar drugs may be associated with brain microbleeds in older adults

13.The new ‘epigenetics:’ Poor nutrition in the womb causes permanent genetic changes in the offspring

14.Low glycemic breakfast may increase benefits of working out

Health Research Report

54th Issue Date 31 MAR 2009

Compiled By Ralph Turchiano

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www.engineeringevil.com

53rd Health Research Report 31 MAR 2009 – Reconstruction

 

Editors Top Five:

1. Common fragrance ingredients in shampoos and conditioners are frequent causes of eczema

2. Frankincense oil — a wise man’s remedy for bladder cancer

3. Review of probiotic trial research finds only Bifantis able to claim efficacy for IBS symptoms

4. Long-term L-carnitine supplementation prevents development of liver cancer

5. Exposure to insecticide may play role in obesity epidemic among some women

In This Issue:

1. Frankincense oil — a wise man’s remedy for bladder cancer

2. Studies show that nice guys finish first in business world

3. Conflicts of interest in clinical research

4. Majority of fire and ambulance recruits overweight

5. Exposure to insecticide may play role in obesity epidemic among some women

6. Cognitive Decline Begins in Late 20s, U.Va. Study Suggests

7. Mayo Clinic study suggests those who have chronic pain may need to assess vitamin D status

8. Gulf War veterans display abnormal brain response to specific chemicals

9. Proteins from garden pea may help fight high blood pressure, kidney disease

10. Licorice extract blocks colorectal cancer in mice

11. Eating red and processed meat associated with increased risk of death

12. Review of probiotic trial research finds only Bifantis able to claim efficacy for IBS symptoms

13. Omega-3 fatty acids reduce risk of advanced prostate cancer

14. Long-term L-carnitine supplementation prevents development of liver cancer

15. New Discovery Raises Doubts About Use of Certain Targeted Therapies in Bladder Cancer

16. Study: Morbidly Obese Sedentary For More Than 99 Percent of Day

17. Common fragrance ingredients in shampoos and conditioners are frequent causes of eczema

18. Tea tree oil and silver together make more effective antiseptics

19. Melatonin may be served as a potential anti-fibrotic drug


Health Research Report

53rd Issue Date 31 MAR 2009

Compiled By Ralph Turchiano

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www.engineeringevil.com

52nd Health Research Report 17 MAR 2009 – Reconstruction

 

 

Editors top five:

1. NCRP Report No. 160 on increased average radiation exposure of the US population

2. Grape Extracts May be Effective Against Harmful Gut Bacteria

3. Not so sweet: Over-consumption of sugar linked to aging

4. Support for adjunctive vitamin C treatment in cancer

5. A diet rich in calcium aids weight loss

 

 

In this Issue:

1. Moderate alcohol intake associated with bone protection

2. NCRP Report No. 160 on increased average radiation exposure of the US population

3. Half in US see another country emerging as world’s technological leader

4. New study shows how spikes in nitrite can have a lasting impact on the heart

5. Normal Human Gut Bacteria May Inhibit Shiga Toxin Development Following Infection with E. coli O157:H7

6. Grape Extracts May be Effective Against Harmful Gut Bacteria

7. Pure fructose frequently confused with high fructose corn syrup

8. Not so sweet: Over-consumption of sugar linked to aging

9. Support for adjunctive vitamin C treatment in cancer

10.’Holy powder’ ingredient makes membranes behave for better health

11. Teenage boys who eat fish at least once a week achieve higher intelligence scores

12. May supplementation of docosahexaenoic acid (DHA)suppress colon tumor cell growth?

13. Vitamin C intake associated with lower risk of gout in men

14. UI study suggests salt might be ‘nature’s antidepressant’

15. Low vitamin D levels associated with several risk factors in teenagers

16. AMERICAN ADULTS FLUNK BASIC SCIENCE

17.Older patients with 1 type of heart failure may receive little or no benefit from drugs

18.A diet rich in calcium aids weight loss

 

Health Research Report

52nd Issue Date 17 MAR 2009

Compiled By Ralph Turchiano

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www.engineeringevil.com

51st Health Research Report 03 MAR 2009 – Reconstructed

Editors Top Five:

 

1. No longer a gray area: Our hair bleaches itself as we grow older

2. Vitamin supplements may protect against noise-induced hearing loss

3. Vitamin B and folic acid may reduce risk of age-related vision loss

4. Broccoli may help protect against respiratory conditions like asthma

5. Cholesterol-reducing drugs may lessen brain function, says ISU researcher

 

 

In this issue:

 

1. Can exercising your brain prevent memory loss?

2. Type of rheumatoid arthritis medication may be associated with increased risk for shingles

3. Research identifies how inflammatory disease causes fatigue

4. Taurine: Key to the visual toxicity of an anti-epileptic drug for children?

5. Vitamin supplements may protect against noise-induced hearing loss

6. Questions of ethics and quality cloud globalization of clinical trials

7. Can breastfeeding reduce multiple sclerosis relapses?

8. When should prostate-specific antigen testing be stopped?

9. Questions of ethics and quality cloud globalization of clinical trials

10. Green, black tea can reduce stroke risk

11. Chili peppers help to unravel the mechanism of pain

12. Vitamin D deficiency may increase risk of colds, flu

13. Vitamin B and folic acid may reduce risk of age-related vision loss

14. No longer a gray area: Our hair bleaches itself as we grow older

15. Cholesterol-reducing drugs may lessen brain function, says ISU researcher

16. Physical fitness improves spatial memory, increases size of brain structure

17. Vegetable-based drug could inhibit melanoma

18. Vitamin A signals offer clues to treating autoimmunity

19. Low levels of vitamin B12 may increase risk for neural tube defects

20. Broccoli may help protect against respiratory conditions like asthma

21. Doctors endorse vegan and vegetarian diets for healthy pregnancies

22. Cleansing toxic waste — with vinegar

23. Are vitamin supplements effective in celiac disease patients? (Yes They Are)

 

Health Research Report

51st Issue Date 03 MAR 2009

Compiled By Ralph Turchiano

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www.engineeringevil.com

 

 

 

50th Health Research Report 17 FEB 2009 – Reconstruction

 

 

 

Editors Top Five:

1. US researchers find traces of toxic mercury in high-fructose corn syrup

2. Arginine discovery could help fight human obesity

3. Even natural perfumes may cause allergies

4. Vigorous Exercise May Help Prevent Vision Loss

5. Indoor plants can reduce formaldehyde levels

 

In this issue:

 

1. Even natural perfumes may cause allergies

2.Researchers Disprove 15-year-old Theory about the Nervous System

3.Plan offers guidance for evaluating menopause-like condition in girls and young women

4. Arginine discovery could help fight human obesity

5. Pharmaceuticals sold in Sweden cause serious environmental harm in India

6. Gut bacteria can manufacture defenses against cancer and inflammatory bowel disease

7. Mutant rats resist warfarin

8. Vigorous Exercise May Help Prevent Vision Loss

9. BGU researchers identify vitamin B12 as an effective canker sore therapy

10. New lab evidence suggests preventive effect of herbal supplement in prostate cancer

11. Herpesvirus: To Vaccinate or Not To Vaccinate Scientists Weigh Risks and Benefits

12. Food counterfeiting, contamination outpace international regulatory systems

13. Arab-American women need supplement to boost dangerously low vitamin D levels

14. Supplement of probiotics provides a new therapy for ulcerative colitis

15. Indoor plants can reduce formaldehyde levels

16. US researchers find traces of toxic mercury in high-fructose corn syrup

Health Research Report

50th Issue Date  17 FEB 2009

Compiled By Ralph Turchiano

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www.engineeringevil.com

 

49th Health Research Report 04 FEB 2009 – Reconstruction

Editors Top Five:

 

1. Stream in India has record high levels of drugs

2. First comprehensive paper on statins’ adverse effects released

3. Hypertension and cholesterol medications present in water released into the St. Lawrence River

4. Rochester study raises new questions about controversial plastics chemical

5. Blue light destroys antibiotic-resistant staph infection

 

 

In this issue:

 

1. Omega-6 fatty acids: Make them a part of heart-healthy eating

2. Hypertension and cholesterol medications present in water released into the St. Lawrence River

3. Stream in India has record high levels of drugs

4. Happiness gap’ in the US narrows

5. CUTTING SALT ISN’T THE ONLY WAY TO REDUCE BLOOD PRESSURE

6. First comprehensive paper on statins’ adverse effects released

7. Daily school recess improves classroom behavior

8. Fast-food diet cancels out benefits of breastfeeding in preventing asthma

9. Exercise no danger for joints

10. Rochester study raises new questions about controversial plastics chemical

11. Exposure to perfluorinated chemicals may reduce women’s fertility

12. Most bacteria from craft goat’s cheese come from lactic acid and could be very beneficial for health

13. Physically Fit Kids Do Better in School

14. Chondroitin Slows Progression and Relieves Symptoms of Knee Osteoarthritis

15. Blue light destroys antibiotic-resistant staph infection

16. Zinc supplements during pregnancy may counteract damage from early alcohol exposure

17. Vitamin D tied to muscle power in adolescent girl

 

Health Research Report

49th Issue Date 04 FEB 2009

Compiled By Ralph Turchiano

www.healthresearchreport.me www.vit.bz

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www.engineeringevil.com

 

 

 

48th Health Research Report 20 JAN 2009 – Reconstruction

 

Editors Top Five:

Not enough research to justify a top five yet.

 

 

In this issue:

 

1. Maslinic acid provides a natural defense against colon cancer

2. Chemopreventive agents in black raspberries identified

3. Study shows California’s autism increase not due to better counting, diagnosis

4. Hormone therapy linked to brain shrinkage, but not lesions

5. Vitamin D is the ‘it’ nutrient of the moment

6. Most heart attack patients’ cholesterol levels did not indicate cardiac risk

7. Misuse of Vicks VapoRub may harm infants and toddlers

8. HHS Report Slams FDA’s Conflict of Interest Oversight

9. Smoking during pregnancy may impair thyroid function of mom and fetus

10. Greater Quadriceps Strength May Benefit Those with Knee Osteoarthritis

11. Seasonal variation in blood pressure

12. Progress made in understanding causes and treatment of endometriosis

13. Study links water pollution with declining male fertility

14. Low-carbohydrate diet burns more excess liver fat than low-calorie diet, UT Southwestern study find

 

Health Research Report

48th Issue Date 20 JAN 2009

Compiled By Ralph Turchiano

www.healthresearchreport.me www.vit.bz

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www.engineeringevil.com

 

46th Health Research Report 23 DEC 2008 – Reconstruction

 

 

 

 

Editors Top Five:

 

 

 

1. Long-term use of diabetes drugs by women significantly increases risk of fractures

 

2. 10% of U.S. High School Seniors Use Vicodin

 

3. Lack of vitamin D causes weight gain and stunts growth in girls

 

New study shows that a cough medicine ingredient could effectively treat prostate cancer

 

5. A low dose of caffeine when pregnant may damage the heart of offspring for a lifetime

 

In this issue:

 

1. Asthma: Commonly used medication shows no clear benefits in children

 

2. Long-term use of diabetes drugs by women significantly increases risk of fractures

 

Lack of vitamin D causes weight gain and stunts growth in girls

 

4. Use weights, not aerobics, to ease back pain

 

5. High pesticide levels found in fruit-based drinks in some countries outside U. S.

 

6. A low dose of caffeine when pregnant may damage the heart of offspring for a lifetime

 

7. 10% of U.S. High School Seniors Use Vicodin

 

8. Vitamin D deficiency in infants and nursing mothers carries long-term disease risks

 

9. New anti-cancer components of extra-virgin olive oil revealed

 

10. Lean muscle mass helps even obese patients battle cancer

 

11. Einstein researchers find convincing evidence that probiotics are effective

 

New study shows that a cough medicine ingredient could effectively treat prostate cancer

 

13. New data regarding safety of artemisinin combination therapy for pregnant women with malaria

 

14. Cousin marriage laws outdated

 

15. New evidence that people make aspirin’s active principle — salicylic acid

 

16. Vitamin D deficiency associated with greater rates of cesarean sections

 

17. UCSB scientists show how certain vegetables combat cancer

 

 

Health Technology Research Synopsis

46th Health Research Report 23 DEC 2008

Compiled By Ralph Turchiano

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www.engineeringevil.com

45th Health Research Report 09 NOV 2008 – Reconstruction

Editors Top Five:

1. Selenium may slow march of AIDS

2. Vitamin B1 could reverse early-stage kidney disease in diabetes patients

3. Persistent pollutant may promote obesity

4. Broccoli compound targets key enzyme in late-stage cancer

5. Down’s symptoms may be treatable in the womb

In this issue:

1. Inhaled corticosteroids raise pneumonia risk for lung disease sufferers

2. Stanford/Packard study shows no benefit from drug widely used to prevent premature births

3. US infant formula safe from melamine, says FDA

4. Vitamin K linked to insulin resistance in older men

5. Down’s symptoms may be treatable in the womb

6. Selenium may slow march of AIDS

7. Fast food a potential risk factor for Alzheimer’s

8. Despite “Apology Laws,” Physicians May Not Communicate Medical Errors

9. Broccoli compound targets key enzyme in late-stage cancer

10. Persistent pollutant may promote obesity

11. Calcium and vitamin D may not be the only protection against bone loss

12. A little wine boosts omega-3 in the body: Researchers find a novel mechanism for a healthier heart

13. Flu vaccine linked to reduced illness, impairment of academic performance among college students (Read WHOLE article),,,

14. Eating eggs when pregnant affects breast cancer in offspring

15. Vitamin D found to fight placental infection

16. Interferon as long-term treatment for hepatitis C not effective, report HALT-C researchers

17. Updated standards to reduce metal contaminants in prescription drugs

18. Breaking the silence after a study ends

19. Vitamin B1 could reverse early-stage kidney disease in diabetes patients

20. Statin warning for pregnant women

21. Pine bark reduces inflammatory marker CRP in osteoarthritis

 

Health Technology Research Synopsis

45th Issue Date 09 NOV 2008

Compiled By Ralph Turchiano

www.healthresearchreport.me www.vit.bz

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www.engineeringevil.com

 

 

 

44th Health Research Report 25 NOV 2008 – Reconstruction

 

Editors Top Five:

1. What cures you may also ail you: Antibiotics, your gut and you

2. Roche ordered to pay $13M to users of acne drug

3. Potassium loss from blood pressure drugs may explain higher risk of adult diabetes

4. 14 drugs identified as most urgently needing study for off-label use, Stanford professor says

5. Pregnancy study finds strong association between two antidepressants and heart anomalies

In this issue:

1. Many doctors plan to quit or cut back: survey

2. Obese kids’ artery plaque similar to middle-aged adults

3. Evolution’s new wrinkle: Proteins with cruise control provide new perspective

4. Mandatory HPV Vaccination Is Unwarranted and Unwise

5. Plastic surgeons warn of malnutrition in body contouring patients

6. Soluble fiber, antispasmodics and peppermint oil should be used to treat IBS

7. Arsenic linked to cardiovascular disease at EPA-regulated drinking water standards

8. Calcium may only protect against colorectal cancer in presence of magnesium

9. Study helps clarify role of vitamin D in cancer therapy

10. What cures you may also ail you: Antibiotics, your gut and you

11. Indigo ointment may help treat patients with psoriasis

12. Broccoli may lower lung cancer risk in smokers

13. Exercise increases brain growth factor and receptors, prevents stem cell drop in middle age

14. Garlic chemical tablet treats diabetes I and II

15. Fake TV News: Widespread and Undisclosed

16. Red, red wine: How it fights Alzheimer’s

17. Roche ordered to pay $13M to users of acne drug

18. Melatonin may save eyesight in inflammatory disease

19. 14 drugs identified as most urgently needing study for off-label use, Stanford professor says

20. Stomach ulcer bug causes bad breath

21. Mineral oil contamination in humans: A health problem?

22. Pregnancy study finds strong association between two antidepressants and heart anomalies

23. Potassium loss from blood pressure drugs may explain higher risk of adult diabetes

24. Feed a cold, feed a fever: Research shows calorie cut makes it harder to fight flu

25. Pain is in the eyes of the beholder

26. Estrogen therapy could be dangerous for women with existing heart risk

Health Technology Research Synopsis

44th Health Research Report 25 NOV 2008

Compiled By Ralph Turchiano

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43rd Health Research Report 11 NOV 2008 – Reconstruction

 

 

 

 

Editors Top Five:

 

 

 

1. Optimal Dose of Vitamin E Maximizes Benefits, Minimizes Risk

 

2. Study shows pine bark reduces jetlag

 

3. Vitamin B3 reduces Alzheimer’s symptoms, lesions

 

4. The upside to allergies: cancer prevention

 

5. Can rectal vitamin E induce remission in patients with mild to moderate ulcerative colitis?

 

 

 

In this Issue:

 

 

 

1. Eating red meat sets up target for disease-causing bacteria

 

2. Grapes may aid a bunch of heart risk factors, animal study finds

 

3. The upside to allergies: cancer prevention

 

4. New MU Study Indicates that Exercise Prevents Fatty Liver Disease

 

5. Vigorous activity protects against breast cancer

 

6. Optimal Dose of Vitamin E Maximizes Benefits, Minimizes Risk

 

7. Drinking milk to ease milk allergy

 

8. Can rectal vitamin E induce remission in patients with mild to moderate ulcerative colitis?

 

9. How did glycine significantly decrease liver injury?

 

10. Fibromyalgia can no longer be called the ‘invisible’ syndrome

 

11. New evidence for homeopathy

 

12. Vitamin B3 reduces Alzheimer’s symptoms, lesions

 

13. Study shows pine bark reduces jetlag

 

14. Dietary sport supplement shows strong effects in the elderly

 

15. UC Davis researchers discover Achilles’ heel in pancreatic cancer

 

16. Could vitamin D save us from radiation?

 

17. LOW POTASSIUM LINKED TO HIGH BLOOD PRESSURE

 

18. Doctors should disclose off-label prescribing to their patients

 

19. Can vitamins and minerals prevent hearing loss?

 

Health Technology Research Synopsis

43rd Issue Date 11 NOV 2008 

Compiled By Ralph Turchiano

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42nd Health Research Report 28 OCT 2008 – Reconstruction

Editors top five:

1. Biotech experts urge industry to work with researchers or risk federal action

2. Splenda may damage gut bacteria, boost weight gain: study

3. What the election means to the nutrition industry?

4. OSTEOPOROSIS DRUGS INCREASE RISK FOR HEART PROBLEMS

5. How drug companies covertly promote off-label drug use

 

 

In this issue:

1. Biotech experts urge industry to work with researchers or risk federal action

2. Fructose Sets Table For Weight Gain Without Warning

3. LEDs may help reduce skin wrinkles, researchers report.

4. 10 Things the Food Industry Doesn’t Want You to Know

5. Do cell phones increase brain cancer risk?

6. US suicide rate increasing

7. Splenda may damage gut bacteria, boost weight gain: study

8. How eating fruit and vegetables can improve cancer patients’ response to chemotherapy

9. Green tea may delay onset of type 1 diabetes

10. Rheumatoid arthritis rising among women

11. OSTEOPOROSIS DRUGS INCREASE RISK FOR HEART PROBLEMS

12. How drug companies covertly promote off-label drug use

13. How toxic environmental chemical DBT affects the immune system

14. ANTISEIZURE DRUG COULD BE FATAL

15. OMEGA-3 FATTY ACID LEVELS MAY AFFECT SLEEP APNEA SEVERITY

16. Methylmercury warning

17. Grapes and grape extracts may lower cardiovascular disease risk, says review in Nutrition Research

18. What the election means to the nutrition industry?

 

Health Technology Research Synopsis

42nd Issue Date 28 OCT 2008

Compiled By Ralph Turchiano

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41st Health Research Report 14 SEP 2008 – Recontsruction

 

Editors Top Five:

 

1. St. John’s wort relieves symptoms of major depression

2. New Study on Effects of Disclosing Financial Interests on Participation in Medical Research

3. Flu vaccine not associated with reduced hospitalizations or outpatient visits among young children

4. Research shows link between bisphenol A and disease in adults

5. Scientists develop new cancer-killing compound from salad plant

 

 

In this issue:

 

1. News media often do not report potential sources of bias in medical research

2. Danish study provides new information on hormone replacement therapy and the risk of heart attacks

3. During exercise, the human brain shifts into high gear on ‘alternative energy’

4. Too many calories send the brain off kilter

5. Second lumpectomy for breast cancer reduces survival rates

6. DNA of good bacteria drives intestinal response to infection

7. New Study on Effects of Disclosing Financial Interests on Participation in Medical Research

8. Disinfectants can make bacteria resistant to treatment

9. Flu vaccine not associated with reduced hospitalizations or outpatient visits among young children

10. Vitamin D deficiency common in patients with IBD, chronic liver disease

11. New studies examine the effectiveness of probiotics in IBS

12. Oral vitamin D may help prevent some skin infections

13. Olive oil ingredient ups the time between meals

14. Red wine may lower lung cancer risk

15. Honey helps to heal wounds

16. Herbal Menopause Therapy a Good Fit for Breast Cancer Patients?

17. Bisphenol A linked to chemotherapy resistance

18. St. John’s wort relieves symptoms of major depression

19. Mouse studies suggest daily dose of ginkgo may prevent brain cell damage after a stroke

20. Children with cystic fibrosis not well covered by guidelines for vitamin D needs

21. Vitamin D a key player in overall health of several body organs, says UC Riverside biochemist

22. Research shows link between bisphenol A and disease in adults

23. Pectin power

24. First evidence that a common pollutant may reduce iodine levels in breast milk

25. Vitamin K does not stem BMD decline in postmenopausal women with osteopenia ((((READ ARTICLE)))

26. Scientists develop new cancer-killing compound from salad plant

27. More Americans have, get treated for high blood pressure

28. Resveratrol prevents fat accumulation in livers of ‘alcoholic’ mice

Health Technology Research Synopsis

41st Issue Date 14 SEP 2008

Compiled By Ralph Turchiano

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40th Health Research Report 30 SEP 2008 – Reconstruction

 

 

Editors Top Five:

 

 

1. Higher urinary levels of commonly used chemical, BPA, linked with cardiovascular disease, diabetes
 
2. Top-selling prescription drug mismarketed to women
 
3. ‘Estrogen flooding our rivers,’ Université de Montréal study
 
4. Honey effective in killing bacteria that cause chronic sinusitis
 
5. Can Taurine be a potent antioxidant drug in the future?

 

 

In this Issue:

 
 
 
1. Higher urinary levels of commonly used chemical, BPA, linked with cardiovascular disease, diabetes
 
2. Research supports correlation between finger lengths and stress hormones
 
3. Colds and flu cut by one-third in study of Canada’s top cold fighter in vaccinated seniors
 
4. Older people who diet without exercising lose valuable muscle mass
 
5. Does probiotic intervention induce the serum global lipid profile change?
 
6. Top-selling prescription drug mismarketed to women
 
7. ‘Estrogen flooding our rivers,’ Université de Montréal study
 
8. Can Taurine be a potent antioxidant drug in the future?
 
9. Statins increase risk of postoperative delirium in elderly patients
 
10. Half of trials supporting FDA applications go unpublished
 
11. Indian spice reduces size of hemorrhagic stroke
 
12. Honey effective in killing bacteria that cause chronic sinusitis
 
13. Dark chocolate: Half a bar per week to keep at bay the risk of heart attack
 
14. Popular COPD treatment increases risk for cardiac events, cardiac death
 
15. Plant antioxidant may protect against radiation exposure
 
16. Isoflavone dietary supplement improves the functioning of the arteries in stroke patients
 
17. Probiotic bacteria can induce monocyte-derived dendritic cells maturation?
 
18. Fishy diet in early infancy cuts eczema risk
 
19. Researchers note differences between people and animals on calorie restriction
 
20. How does ellagic acid exert anti-cancer effect on pancreatic cancer cells?
 
21. Animals farmed for meat are the No. 1 source of food poisoning bug, study shows
 
22. Cholesterol-lowering drugs and the effect on muscle repair and regeneration
 
23. Majority of children vaccinated against hepatitis B not at increased risk of MS
 
24. Researchers study how pistachios may improve heart health
 
25. Blood thinning drug linked to increased bleeding in brain
 
26. New study proves that pain is not a symptom of arthritis, pain causes arthritis
 
 

Health Technology Research Synopsis

40th Issue Date 30 SEP 2008

Compiled By Ralph Turchiano

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39th Health Research Report 16 SEP 2008 – Reconstruction

Editors Top Five:

1. Substance found in fruits and vegetables reduces likelihood of the flu

2. New study will make criminals sweat

3. Common bronchodilator linked to increased deaths

4. Higher urinary levels of commonly used chemical, BPA, linked with cardiovascular disease, diabetes

5. FDA defends plastic linked with health risks

In this issue:

1. Loss of sleep, even for a single night, increases inflammation in the body

2. Study finds B-vitamin deficiency may cause vascular cognitive impairment

3. Innate immune system targets asthma-linked fungus for destruction

4. New study reveals higher protein breakfast may help dieters stay on track

5. Substance found in fruits and vegetables reduces likelihood of the flu

6. Oxidative Stress: Mechanism of Cell Death Clarified

7. Study shows pine bark naturally reduces knee osteoarthritis

8. Vitamin B12 may protect the brain in old age

9. Fluctuations in serotonin transport may explain winter blues

10. Diet may eliminate spasms for infants with epilepsy

11. Calcium during pregnancy reduces harmful blood lead levels

12. Eating fish while pregnant, longer breastfeeding, lead to better infant development

13. Is yakult helpful in the treatment of irritable bowel syndrome?

14. New research could hold the key to keeping older people fit for longer

15. COPD? Eat your veggies

16. Drinking chamomile tea may help fight complications of diabetes

17. Study highlights underlying reasons for why patients are missing their supplementation

18. New study will make criminals sweat

19. Avoid coupon redeemers: Their stigma is contagious (unless they’re attractive)

20. Is re-emerging superbug the next MRSA?

21. Common bronchodilator linked to increased deaths

22. Higher urinary levels of commonly used chemical, BPA, linked with cardiovascular disease, diabetes

23. Expert urges FDA to take action to reduce BPA exposure

24. FDA defends plastic linked with health risks

Health Technology Research Synopsis

39th Issue Date 16 SEP 2008

Compiled By Ralph Turchiano

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38th Health Research Report 02 SEP 2008 – Reconstruction

Editors Top Five:

 

1.      How to stop a new type of heart attack
2.      Flu shot does not cut risk of death in elderly
3.      Scientists discover leptin can also aid type 1 diabetics
4.      Killer carbs — Monash scientist finds the key to overeating as we age
5.      Low cholesterol associated with cancer in diabetics

 

In This Issue:

 
1.      Silver-coated endotracheal tubes appear to reduce risk of pneumonia associated with ventilator use
2.      Arsenic exposure could increase diabetes risk
3.      Low level cadmium exposure linked to lung disease
4.      79 million US adults have medical bill problems or are paying off medical debt
5.      How to stop a new type of heart attack
6.      New research suggests diabetes transmitted from parents to children
7.      Positive thinking may protect against breast cancer
8.      Killer carbs — Monash scientist finds the key to overeating as we age
9.      The big gulp: consumers avoid extremes in soda sizes
10.  Low cholesterol associated with cancer in diabetics
11.  Anti-psychotic drug use in the elderly increases despite drug safety warnings
12.  New study shows health benefits of probiotic could extend to the entire body
13.  Anti-Cancer Flower Power
14.  Oral Administration of Lactobacillus from Breast Milk May Treat Common Infection in Lactating Mothers
15.  Scientists discover leptin can also aid type 1 diabetics
16.  Flu shot does not cut risk of death in elderly
17.  Researchers find high levels of toxic metals in herbal medicine products sold online
18.  Caesarean babies more likely to develop diabetes
19.  Olive leaf extract can help tackle high blood pressure and cholesterol
20.  Why do eyelids sag with age? UCLA study answers mystery
21.  New evidence on addiction to medicines Diazepam has effect on nerve cells in the brain reward system
22.  Study examines use of opioids
23.  Heart attack patients who stop statin risk death, say McGill researchers
24.  All types of antipsychotic drugs increase the risk of stroke
25.  Class of diabetes drugs carries significant cardiovascular risks
26.  National Study Shows Magnesium Sulfate Reduces Risk of Cerebral Palsy in Premature Births
27.  Sex hormones link to heart risk
28.  Large-scale Survey Links “Burnout” to Suicidal Thoughts in Med Students
29.  New evidence on folic acid in the diet and colon cancer
30.  Survey: ‘Tanorexia’ common among university students
31.  Post-marketing studies finding adverse events in drugs used in children
32.  Most vaccine-allergic children can still be safely vaccinated, Hopkins experts say
33.  Higher anaphylaxis rates after HPV vaccination: CMAJ study
34.  Safety of antithrombotic treatment in acute coronary syndromes
35.  Study finds B-vitamin deficiency may cause vascular cognitive impairment

Health Technology Research Synopsis

38th Issue Date 02 SEP 2008

Compiled By Ralph Turchiano

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36th Health Research Report 05 AUG 2008 – Reconstruction

 

Editors Top Five:

 
1.      Toxic drugs, toxic system: Sociologist predicts drug disasters
2.      Study Suggests 86 Percent of Americans Could be Overweight or Obese by 2030
3.      Flu vaccine may not protect seniors well
4.      Chronic exposure to estrogen impairs some cognitive functions
5.      Vitamin C injections slow tumor growth in mice

 

 

In this issue:
1.      Is sun exposure a major cause of melanoma?
2.      Soy foods are associated with lower sperm concentrations
3.      Toxic chemicals found in common scented laundry products, air fresheners
4.      Exercise could be the heart’s fountain of youth
5.      Gummy bears that fight plaque
6.      Japanese diet rich in fish may hold secret to healthy heart
7.      At-Home Deaths from Combining Rx Drugs, Street Drugs and/or Alcohol Skyrocket By More Than 3,000 Percent
8.      Dietary factors appear to be associated with diabetes risk
9.      Foods high in conjugated linoleic acids can enrich breast milk
10.  OSU STUDY SHOWS EXPOSURE TO BAD AIR RAISES BLOOD PRESSURE
11.  Compound that helps rice grow reduces nerve, vascular damage from diabetes
12.  Study Suggests 86 Percent of Americans Could be Overweight or Obese by 2030
13.  Hey fever! The surprise benefit of allergies
14.  Frankincense provides relief to arthritis sufferers
15.  Cholesterol-lowering drug boosts bone repair
16.  Experts continue to cite Bifantis as promising probiotic treatment for Irritable Bowel Syndrome
17.  Exercise in a pill
18.  Flu vaccine may not protect seniors well
19.  New Study Shows Compounds From Soy Affect Brain and Reproductive Development
20.  Physicians ask EPA, ‘Antibiotics to cure sick apples, or sick children?’
21.  Schizophrenia researchers welcome new blood
22.  Outdoor Activity and Nearsightedness in Children
23.  Chronic exposure to estrogen impairs some cognitive functions
24.  Toxic drugs, toxic system: Sociologist predicts drug disasters
25.  Task Force Finds No Prostate Screening Benefit for Men Over 75
26.  Eating fish may prevent memory loss and stroke in old age
27.  Canadian study of colds and kids: Positive safety results for ginseng extract
28.  Vitamin C injections slow tumor growth in mice
29.  Adults who eat eggs for breakfast lose 65 percent more weight
30.  Sesame seed extract and konjac gum may help ward off Salmonella and E. coli
31.  In era of pills, fewer shrinks doing talk therapy
 

Health Technology Research Synopsis

36th Issue Date 05 AUG 2008

Compiled By Ralph Turchiano

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35th Health Research Report 22 JUL 2008 – Reconstruction

 

Editors Top Five:

1. Environmental pollutant has sex-skewing effect

2. Stomach bug appears to protect kids from asthma, says NYU study

3. Cranberry juice creates energy barrier that keeps bacteria away from cells, study shows

4. 89 percent of children’s food products provide poor nutritional quality

5. Schering-Plough, Merck’s Vytorin misses study goal

 

 

In This Issue:

1. Androgen deprivation therapy for localized prostate cancer not associated with improved survival

2. Male cyclists risk sexual problems if they don’t choose the right bike

3. Aerosol toxins from red tides may cause long-term health threat

4. Scientists learn how food affects the brain

5. Risk of gall bladder disease with HRT patches lower than with HRT pills

6. 89 percent of children’s food products provide poor nutritional quality

7. Stomach bug appears to protect kids from asthma, says NYU study

8. Consumption of nut products during pregnancy linked to increased asthma in children

9. Environmental pollutant has sex-skewing effect

10. Possible link found between x-rays and prostate cancer

11. Study: Regular walking nearly halves elderly disability risk

12. The epigenetics of increasing weight through the generations

13. Removing ovaries during hysterectomy: Effects remain unknown

14. Cranberry juice creates energy barrier that keeps bacteria away from cells, study shows

15. Scientists identify how gastric reflux may trigger asthma

16. Schering-Plough, Merck’s Vytorin misses study goal

Health Technology Research Synopsis

35th Issue Date 22 JUL 2008

Compiled By Ralph Turchiano

www.healthresearchreport.me www.vit.bz

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www.engineeringevil.com

 

 

 

 

32nd Health Research Report 11 JUN 2008 – Reconstructed

32nd Health Research Report 11 JUN 2008 – Reconstructed

 

 

 

Editors Top Five:

 
1.      US reporters often do a poor job of reporting about new medical treatments
2.      Pycnogenol improved diabetes control and reduced antihypertensive medications
3.      How advanced prostate cancer becomes resistant to androgen-deprivation therapy
4.      Is tap water safe for expectant mothers?
5.      The good news in our DNA: Defects you can fix with vitamins and minerals

 

 

In this issue:

 
1.      Childhood lead exposure associated with criminal behavior in adulthood
2.      US reporters often do a poor job of reporting about new medical treatments
3.      People with ADHD do 1 month’s less work per year
4.      Combining exercise with hormone could prevent weight gain
5.      Estrogen Helps Drive Distinct, Aggressive Form of Prostate Cancer
6.      New breathing exercises help manage asthma
7.      Intestinal bacteria promote — and prevent — inflammatory bowel disease
8.      New vegetarian food with several benefits
9.      Pycnogenol improved diabetes control and reduced antihypertensive medications
10.  Dehydrated tomatoes show promise for preventing prostate cancer
Exercise cuts cancer death in men
12.  US soldiers in high-tuberculosis areas face new epidemic: false positives
13.  Whole milk is effective and cost-effective as oral contrast agent
14.  How advanced prostate cancer becomes resistant to androgen-deprivation therapy
15.  Bisphenol A: Controversy over widely used plastics chemical spurs product changes, regulatory debate
16.   Vitamins Help Prevent Vision Loss from AMD—If Used Correctly
17.  The good news in our DNA: Defects you can fix with vitamins and minerals
18.  Is tap water safe for expectant mothers?
19.  Despite vaccine, public should not get complacent about pneumococcal disease
20.  Agent in red wine found to keep hearts young
21.  Increased Incidence of Melanoma Found in Rheumatoid Arthritis Patients Treated with Methotrexate
22.  Long-term pesticide exposure may increase risk of diabetes
23.  Moores UCSD Cancer Center study links vitamin D, type 1 diabetes
24.  Another new wrinkle in treating skin aging
25.  Study finds Chinese food good for your heart
26.  Men with vitamin D deficiency may have increased risk of heart attack
27.  Eating fish and foods with omega-3 fatty acids linked to lower risk of age-related eye disease
28.  World’s oldest woman had normal brain
29.  Solid tumor cells not killed by radiation and chemotherapy become stronger
30.  Common bowel problem linked to chili pepper pain receptor
 
 

 

 

Health Technology Research Synopsis

32nd Issue Date 11 JUN 2008

Compiled By Ralph Turchiano

www.healthresearchreport.me www.vit.bz

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www.engineeringevil.com