Blood Sugar Lowered Dramatically with AMPK Raising Alanine

Blood Sugar Lowered Dramatically with AMPK Raising Alanine

Blood Sugar Lowered Dramatically with AMPK Raising Alanine

Type 2 diabetes is driven by many metabolic pathways, with some pathways driven by amino acids, the molecular building blocks for proteins. Scientists at Joslin Diabetes Center now have shown that one amino acid, alanine, may produce a short-term lowering of glucose levels by altering energy metabolism in the cell.

Yusuke Adachi, Ana Luisa De Sousa-Coelho, Ikue Harata, Charlie Aoun, Sandra Weimer, Xu Shi, Karina N. Gonzalez Herrera, Hirokazu Takahashi, Chris Doherty, Yasushi Noguchi, Laurie J. Goodyear, Marcia C. Haigis, Robert E. Gerszten, Mary-Elizabeth Patti. l-Alanine activates hepatic AMP-activated protein kinase and modulates systemic glucose metabolism. Molecular Metabolism, 2018; DOI: 10.1016/j.molmet.2018.08.002

AMPK, TYPE 2 Diabetes, alanine, glucose, insulin, Adenosine monophosphate-activated protein kinase, energy, glucose tolerance, ala, Krebs cycle, diabetes,

Author: Ralph Turchiano

In short, I review clinical research on an almost daily basis. What I post tends to be articles that are relevant to the readers in addition to some curiosities that have intriguing potential. As a hobby, I truly enjoy the puzzle-solving play that statistics and programming as in the python language bring to the table. I just do not enjoy problem-solving, I love problem-solving and the childlike inspiration and exploration of that innocent exhilaration of discovering something new. Enjoy ;-)