Vitamin D may be more effective than masks and distancing combined for COVID ?

Vitamin D may be more effective than masks and distancing combined for COVID ?

In patients older than 40 years they observed that those patients who were vitamin D sufficient were 51.5 percent less likely to die from the infection compared to patients who were vitamin D deficient or insufficient with a blood level of 25-hydroxyvitamin D less than 30 ng/mL.

Holick, who most recently published a study which found that a sufficient amount of vitamin D can reduce the risk of catching coronavirus by 54 percent, believes that being vitamin D sufficient helps to fight consequences from being infected not only with the corona virus but also other viruses causing upper respiratory tract illnesses including influenza. “There is great concern that the combination of an influenza infection and a coronal viral infection could substantially increase hospitalizations and death due to complications from these viral infections.”

#covid19 #sarscov2 #vitaminD

Kaufman HW, Niles JK, Kroll MH, Bi C, Holick MF (2020) SARS-CoV-2 positivity rates associated with circulating 25-hydroxyvitamin D levels. PLOS ONE 15(9): e0239252. https://doi.org/10.1371/journal.pone.0239252

COVID-19 Made worse By Social Distancing?

We are led to question whether the recommended social distancing measures to prevent SARS-CoV-2 transmission could increase the number of other serious instabilities. The breaking of the contagion pathways reduces the sharing of microorganisms between people, thus favoring dysbiosis, which, in turn, may increase the poor prognosis of the disease. #covid #microbiome #dysbiosis Célia P. F. Domingues, João S. Rebelo, Francisco Dionisio, Ana Botelho, Teresa Nogueira. The Social Distancing Imposed To Contain COVID-19 Can Affect Our Microbiome: a Double-Edged Sword in Human Health. mSphere, 2020; 5 (5) DOI: 10.1128/mSphere.00716-20 https://msphere.asm.org/content/5/5/e00716-20

COVID-19 Tracking Data API and Data Anomalies (No Correlations? Cases to Hospitalizations Increases)

Is there a correlation between Positive cases and Hospitalizations? Below is the API for python access, open to all who desire to filter the data. I want to just give easy access to all the beginner students data scientists out there, such as myself..Explore and Discover: **My Apologies It says High Def, but does not look High Def on video here**

Code: import matplotlib.pyplot as plt import pandas as pd from scipy import stats import statsmodels.api as sm import requests import time from IPython.display import clear_output response = requests.get(“https://covidtracking.com/api/v1/us/daily.csv”) covid = response.content ccc = open(“daily.csv”,”wb”) ccc.write(covid) ccc.close() df = pd.read_csv(“daily.csv”, index_col = ‘date’) df.head() data = df[[‘positiveIncrease’,’hospitalizedIncrease’]] dataT = df[[‘positiveIncrease’,’hospitalizedIncrease’,’hospitalizedCurrently’]] dataD = df[[‘hospitalizedIncrease’,’deathIncrease’]] dataT.head(20) plt.figure(figsize=(20,10)) Y = data[‘positiveIncrease’] X = data[‘hospitalizedIncrease’] plt.scatter(X,Y) plt.ylabel(“Tested Positive Increase”) plt.xlabel(“Hospitalization Increase”) plt.show() Y1 = sm.add_constant(Y) reg = sm.OLS(X, Y1).fit() reg.summary() data.plot(y=[‘hospitalizedIncrease’,’positiveIncrease’],xticks=data.index[0:len(data):30], rot=90, figsize=(20,10) ) for x in range(len(data)): plt.figure(figsize=(20,10)) plt.xticks( data.index.values[0:len(data):30], rotation = 90, fontsize=20 ) plt.plot(data.tail(x))

Honeysuckle Decoction Inhibits SARS-CoV-2

In a new study in Cell Discovery, Chen-Yu Zhang’s group at Nanjing University and two other groups from Wuhan Institute of Virology and the Second Hospital of Nanjing present a novel finding that absorbed miRNA MIR2911 in honeysuckle decoction (HD) can directly target SARS-CoV-2 genes and inhibit viral replication. Drinking of HD accelerate the negative conversion of COVID-19 patients.

#mir2911 #sarcov2 #honeysuckle

Zhou, L., Zhou, Z., Jiang, X. et al. Absorbed plant MIR2911 in honeysuckle decoction inhibits SARS-CoV-2 replication and accelerates the negative conversion of infected patients. Cell Discov 6, 54 (2020). https://doi.org/10.1038/s41421-020-00197-3

https://www.nature.com/articles/s41421-020-00197-3#ethics

In cell studies, seaweed extract outperforms remdesivir in blocking COVID-19 virus

In a test of antiviral effectiveness against the virus that causes COVID-19, an extract from edible seaweeds substantially outperformed remdesivir, the current standard antiviral used to combat the disease.

Paul S. Kwon, Hanseul Oh, Seok-Joon Kwon, Weihua Jin, Fuming Zhang, Keith Fraser, Jung Joo Hong, Robert J. Linhardt, Jonathan S. Dordick. Sulfated polysaccharides effectively inhibit SARS-CoV-2 in vitro. Cell Discovery, 2020; 6 (1) DOI: 10.1038/s41421-020-00192-8

#fucoidan #covid19 #heparin

https://www.nature.com/articles/s41421-020-00192-8

Selenium and COVID-19 A Strong Survival Correlation & New Drug Discoveries

Selenium and COVID-19 A Strong Survival Correlation & New Drug Discoveries

Quote “Our results show an association between the reported cure rates for COVID-19 and selenium status. These data are consistent with the evidence of the antiviral effects of selenium from previous studies”

#COVID19 #SARCOV2 #SELENIUM

Margaret P Rayman, Ramy Saad, Kate Bennett, Ethan Will Taylor, Jinsong Zhang. Association between regional selenium status and reported outcome of COVID-19 cases in China. The American Journal of Clinical Nutrition, 2020; DOI: 10.1093/ajcn/nqaa095

https://academic.oup.com/ajcn/advance-article/doi/10.1093/ajcn/nqaa095/5826147

Onat Kadioglu, Mohamed Saeed, Henry Johannes Greten, Thomas Efferth. Identification of novel compounds against three targets of SARS CoV-2 coronavirus by combined virtual screening and supervised machine learning. Bulletin of the World Health Organization, March 21, 2020; DOI: 10.2471/BLT.20.255943

https://www.who.int/bulletin/online_first/20-255943.pdf

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COVID-19 Updated Nutritional Supplement Research

COVID-19 Updated Nutritional Supplement Research

Dietary supplements an important weapon for fighting off COVID-19

Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections Nutrients 2020, 12(4), 1181; https://doi.org/10.3390/nu12041181

https://www.mdpi.com/2072-6643/12/4/1181/htm

Ayurveda and yoga for COVID-19 prevention

Public Health Approach of Ayurveda and Yoga for COVID-19 Prophylaxis Published Online:20 Apr 2020https://doi.org/10.1089/acm.2020.0129

https://www.liebertpub.com/doi/10.1089/acm.2020.0129

#Ashwagandha, #Dietarysupplements, #sars-cov-2

Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area JAMA. Published online April 22, 2020. doi:10.1001/jama.2020.6775

https://jamanetwork.com/journals/jama/fullarticle/2765184?guestAccessKey=906e474e-0b94-4e0e-8eaa-606ddf0224f5

Eurekalet

https://www.eurekalert.org/

Science Daily

https://www.sciencedaily.com/

Annals of Internal Medicine

https://annals.org/

Ayurveda, sars-cov-2, yoga, dietary supplements, immune system, , dosage, zinc, omega-3, dha, epa, nutritional status, mechanical ventilator, mortality, vitamin e, SARS coronavirus 2, Prophylaxis, immune system; viral infection; influenza; COVID-19; micronutrients, vitamins, omega-3 fatty acids, minerals, vitamin C, vitamin D, influenza, flu, virus,

COVID-19 Powerful Disinfectants, Simple and Studied WHO Formulations

COVID-19 Powerful Disinfectants, Simple and Studied WHO Formulations

“We showed that both WHO-recommended formulations sufficiently inactivate the virus after 30 seconds,” as Stephanie Pfänder sums up the results. Plus, this does not merely apply to the WHO solutions; rather, their main components, the alcohols ethanol and isopropanol, also showed adequate inactivation of the virus.

#COVID19 #SARSCOV2 #Disinfectant

Disinfectant I

80 volume percent ethanol,

1.45 volume percent glycerine

0.125 volume percent hydrogen peroxide.

Disinfectant II

75 volume percent isopropanol,

1.45 volume percent glycerine

0.125 volume percent hydrogen peroxide

Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 by WHO-Recommended Hand Rub Formulations and Alcohols dx.doi.org/10.3201/eid2607.200915

https://wwwnc.cdc.gov/eid/article/26/7/20-0915_article

(non verified) Department of Homeland Security COVID-19 Science and Technology Report.

Scribd link : https://www.scribd.com/document/456897616/DHSST#download

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COVID-19 STRONG CORRELATION WITH VITAMIN D DEFICIENCY

COVID-19 STRONG CORRELATION WITH VITAMIN D DEFICIENCY

In conclusion, we found significant relationships between vitamin D levels and the number COVID–19 cases and especially the mortality caused by this infection. The most vulnerable group of population for COVID–19 is also the one that has the most deficit in Vitamin D.

**Physical Distance NOT Social Distance Commentary

#vitaminD #covid19 #sarscov2

The role of Vitamin D in the prevention of Coronavirus Disease 2019 infection and mortality DOI:10.21203/rs.3.rs-21211/v1

https://www.researchsquare.com/article/rs-21211/v1

COVID-19: Genetic network analysis provides ‘snapshot’ of pandemic origin

https://www.eurekalert.org/pub_releases/2020-04/uoc-cgn040820.php#.XpOpCYt69MY.wordpress

Vitamin D deficiency in Ireland– implications for COVID-19.Results from The Irish Longitudinal Study on Ageing (TILDA)

https://tilda.tcd.ie/publications/reports/pdf/Report_Covid19VitaminD.pdf

The Functional Medicine Approach to COVID-19: Virus-Specific Nutraceutical and Botanical Agents

https://www.ifm.org/news-insights/the-functional-medicine-approach-to-covid-19-virus-specific-nutraceutical-and-botanical-agents/

Researchers find low magnesium levels make vitamin D ineffective

https://www.eurekalert.org/pub_releases/2018-02/aoa-rfl022318.php

https://www.youtube.com/watch?v=MfLJkzkDpfU&t=1s

Suicide Mortality and Coronavirus Disease 2019—A Perfect Storm?

https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2764584?widget=personalizedcontent&previousarticle=2764583

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COVID-19 Completely Eradicated by Ivermectin plus other Updates

Scientists from Monash University in Melbourne showed that a single dose of the drug, Ivermectin, could stop the SARS-CoV-2 virus growing in cell culture – effectively eradicating all genetic material of the virus within 48 hours.

#COVID19 #ivermectin #SARSCOV2

Leon Caly, Julian D. Druce, Mike G. Catton, David A. Jans, Kylie M. Wagstaff. The FDA-approved Drug Ivermectin inhibits the replication of SARS-CoV-2 in vitro. Antiviral Research, 2020; 104787 DOI: 10.1016/j.antiviral.2020.104787

https://www.sciencedirect.com/science/article/pii/S0166354220302011

Plus:

Neither surgical nor cotton masks effectively filter SARS COV-2

https://www.eurekalert.org/pub_releases/2020-04/acop-nsn040620.php#.XovOBRRTKEE.wordpress

Studies use SIRD model to forecast COVID-19 spread

https://www.eurekalert.org/pub_releases/2020-03/p-tcp033120.php#.Xoki007bc90.wordpress

COVID-19 New Drug Concerns, Research Breakthroughs And Updated Mortality Statistics

COVID-19 New Drug Concerns, Research Breakthroughs And Updated Mortality Statistics

A brief look at glucocorticoids, the Lancets updated mortality statistics, Hydroxychloroquine risks, lung treatments, viral treatment, and stem cell treatments

The Lancet Infectious Diseases: Comprehensive COVID-19 hospitalisation and death rate estimates help countries best prepare as global pandemic unfolds

https://www.eurekalert.org/pub_releases/2020-03/tl-pss_1033020.php#.XoKIMrdEpR0.wordpress

Mayo Clinic outlines approach for patients at risk of drug-induced sudden cardiac death in COVID-19

https://ekaprdweb01.eurekalert.org/pub_releases/2020-03/mc-mco032520.php

Individuals taking class of steroid medications at high risk for COVID-19

https://www.eurekalert.org/pub_releases/2020-03/tes-itc033120.php

Perhaps we will not need all the ventilators after all

https://www.eurekalert.org/pub_releases/2020-03/au-pww032620.php

HSC professor on team using stem cells to combat COVID-19 pneumonia

https://www.eurekalert.org/pub_releases/2020-03/uont-hpo032920.php

Nafamostat is expected to prevent the transmission of new coronavirus infection (COVID-19)

https://www.eurekalert.org/pub_releases/2020-03/tiom-nie032420.php

Researchers investigate potential treatments for COVID-19

https://ekaprdweb01.eurekalert.org/pub_releases/2020-03/asfm-rip032620.php

COVID-19: Stopgap measure to treat respiratory distress

https://www.eurekalert.org/pub_releases/2020-03/miot-asm032520.php

COVID-19 Infection and Mortality Rate Questions

COVID-19 Infection and Mortality Rate Questions

Person-to-person transmission of SARS-CoV-2 occurred between two people with prolonged, unprotected exposure while the first patient was symptomatic. Despite active monitoring and testing of 372 contacts of both cases, no further transmission was detected

The RKI added: ‘We don’t consider post-mortem tests to be a decisive factor.

‘We work on the principle that patients are tested before they die.’

But this means that if a person dies in quarantine at home and does not go to hospital, there is a high chance they will not be included in the statistics, as Giovanni Maga of Italy’s National Research Council pointed out in an interview with Euronews

First known person-to-person transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the USA. The Lancet, 2020; DOI: 10.1016/S0140-6736(20)30607-3

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30607-3/fulltext

COVID-19 and the Risk to Health Care Workers: A Case Report

Published: Ann Intern Med. 2020. DOI: 10.7326/L20-0175

https://annals.org/aim/fullarticle/2763329/covid-19-risk-health-care-workers-case-report

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