Brain Radiation Damage Reversed With Lithium
“From this, we conclude that lithium, given along the lines of this model, can help to heal the damage caused by radiotherapy, even long after it was caused,” says lead author Giulia Zanni, postdoctoral researcher at Columbia University and former PhD student in Klas Blomgren’s group at Karolinska Institutet.
#radiation #lithium #heal
Giulia Zanni, Shinobu Goto, Adamantia F. Fragopoulou, Giulia Gaudenzi, Vinogran Naidoo, Elena Di Martino, Gabriel Levy, Cecilia A. Dominguez, Olga Dethlefsen, Angel Cedazo-Minguez, Paula Merino-Serrais, Antonios Stamatakis, Ola Hermanson, Klas Blomgren. Lithium treatment reverses irradiation-induced changes in rodent neural progenitors and rescues cognition. Molecular Psychiatry, 2019; DOI: 10.1038/s41380-019-0584-0
Bone, not adrenaline, drives fight or flight response
A new study from Columbia researchers suggests that bony vertebrates can’t muster this response to danger without the skeleton. The researchers found in mice and humans that almost immediately after the brain recognizes danger, it instructs the skeleton to flood the bloodstream with the bone-derived hormone osteocalcin, which is needed to turn on the fight or flight response
Julian Meyer Berger, Parminder Singh, Lori Khrimian, Donald A. Morgan, Subrata Chowdhury, Emilio Arteaga-Solis, Tamas L. Horvath, Ana I. Domingos, Anna L. Marsland, Vijay Kumal Yadav, Kamal Rahmouni, Xiao-Bing Gao, Gerard Karsenty. Mediation of the Acute Stress Response by the Skeleton. Cell Metabolism, 2019; DOI: 10.1016/j.cmet.2019.08.012
#osteocalcin #stress #asr
Cognitive decline reversed 30 years in 6 weeks
After just 1 ½ months, participants increased their cognitive abilities to levels similar to those of middle-aged adults, 30 years younger. Control group members, who did not take classes, showed no change in their performance. “The participants in the intervention bridged a 30 year difference in cognitive abilities after just 6 weeks and maintained these abilities while learning multiple new skills,” said Wu, who is an assistant professor of psychology
Shirley Leanos, Esra Kürüm, Carla M Strickland-Hughes, Annie S Ditta, Gianhu Nguyen, Miranda Felix, Hara Yum, George W Rebok, Rachel Wu. The Impact of Learning Multiple Real-World Skills on Cognitive Abilities and Functional Independence in Healthy Older Adults. The Journals of Gerontology: Series B, 2019; DOI: 10.1093/geronb/gbz084
#cognitive #episodic #reversal
The study to be published on 19 July 2018 found that cumulative RF-EMF brain exposure from mobile phone use over one year may have a negative effect on the development of figural memory performance in adolescents, confirming prior results published in 2015.
Foerster M., Thielens A., Joseph W., Eeftens M., Röösli M. A prospective cohort study of adolescents’ memory performance and individual brain dose of microwave radiation from wireless communication. Environmental Health Perspectives, 2018 DOI: 10.1289/EHP2427
Cell phone, emf, rf-emf, memory, right hemisphere, brain, adolescents, absorbed, brain dose, radiofrequency electromagnetic fields, mobile phone, Figural memory
The hippocampus lost about 30 percent of capacity in low light in just 4 weeks as well as a steep decline in brain derived neurotrophic factor (Animal Model)
* Grass rats were housed in either a 12: 12 h bright light–dark (brLD, 1,000 lux) or dim light-dark (dimLD, 50 lux) cycle.
Light modulates hippocampal function and spatial learning in a diurnal rodent species: A study using male nile grass rat (Arvicanthis niloticus)DOI: 10.1002/hipo.22822