Copper nanoparticles and immunotherapy rapidly eliminate cancer cells – Pilot Study

Copper nanoparticles and immunotherapy rapidly eliminate cancer cells – Pilot Study

The combination of the nanoparticles and immunotherapy made the tumours disappear entirely and, as a result, works as a vaccine for lung and colon cancer – the two types that were investigated in the study. To confirm their finding, the researchers injected tumour cells back into the mice. These cells were immediately eliminated by the immune system, which was on the lookout for any new, similar, cells invading the body.

#copper #cancer #immunotherapy

Hendrik Naatz, Bella B. Manshian, Carla Rios Luci, Vasiliki Tsikourkitoudi, Yiannis Deligiannakis, Johannes Birkenstock, Suman Pokhrel, Lutz Mädler, Stefaan J. Soenen. Model-Based Nanoengineered Pharmacokinetics of Iron-Doped Copper Oxide for Nanomedical Applications. Angewandte Chemie International Edition, 2020; DOI: 10.1002/anie.201912312

https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201912312

Creatine powers the immune system to fight cancer

Creatine powers the immune system to fight cancer

Creatine powers the immune system to fight cancer

The energy-buffering function of creatine certainly goes beyond regulating CD8 T cells. In CrT-KO mice, we have observed the hyporesponsiveness of multiple immune cells in various mouse tumor models. It is also likely that creatine regulates immune reactions to multiple diseases beyond cancer, such as infections and autoimmune diseases (Riesberg et al., 2016). Studying the roles of creatine in modulating various immune cells under different health and disease conditions will be interesting topics for future research.

Stefano Di Biase, Xiaoya Ma, Xi Wang, Jiaji Yu, Yu-Chen Wang, Drake J. Smith, Yang Zhou, Zhe Li, Yu Jeong Kim, Nicole Clarke, Angela To, Lili Yang. Creatine uptake regulates CD8 T cell antitumor immunity. The Journal of Experimental Medicine, 2019; jem.20182044 DOI: 10.1084/jem.20182044

#creatine #tumors #cancer

http://jem.rupress.org/content/early/2019/10/17/jem.20182044/tab-metrics

Strawberry tree honey may inhibit colon cancer

Strawberry tree honey may inhibit colon cancer

Strawberry tree honey may inhibit colon cancer

Spanish and Italian researchers have proven that when honey from strawberry trees, a product typical of Mediterranean areas, is added to colon cancer cells grown in the laboratory, cell proliferation is stopped.

Sadia Afrin et al. Strawberry tree honey as a new potential functional food. Part 1: Strawberry tree honey reduces colon cancer cell proliferation and colony formation ability, inhibits cell cycle and promotes apoptosis by regulating EGFR and MAPKs signaling pathways, Journal of Functional Foods (2019). DOI: 10.1016/j.jff.2019.04.035

#strawberrytreehoney #coloncancer #cancer

https://www.sciencedirect.com/science/article/pii/S1756464619302221

Eating Nuts may dramatically improve Colon Cancer outcomes

Eating Nuts may dramatically improve Colon Cancer outcomes

 

Those who regularly consumed at least two, one-ounce servings of nuts each week demonstrated a 42% improvement in disease-free survival and a 57% improvement in overall survival.

Nut Consumption and Survival in Patients With Stage III Colon Cancer: Results From CALGB 89803 (Alliance). Journal of Clinical Oncology, 2018; JCO.2017.75.541 DOI: 10.1200/JCO.2017.75.5413