Complete Survival when lethal Bacteria are fed rather than killed (Proof of Concept )

Complete Survival when lethal Bacteria are fed rather than killed (Proof of Concept )

Complete Survival when lethal Bacteria are fed rather than killed (Proof of Concept )

Researchers report that giving mice dietary iron supplements enabled them to survive a normally lethal bacterial infection and resulted in later generations of those bacteria being less virulent. The approach demonstrates in preclinical studies that non-antibiotic-based strategies — such as nutritional interventions — can shift the relationship between the patient and pathogens away from antagonism and toward cooperation.

Karina K. Sanchez, Grischa Y. Chen, Alexandria M. Palaferri Schieber, Samuel E. Redford, Maxim N. Shokhirev, Mathias Leblanc, Yujung M. Lee, Janelle S. Ayres. Cooperative Metabolic Adaptations in the Host Can Favor Asymptomatic Infection and Select for Attenuated Virulence in an Enteric Pathogen. Cell, 2018; DOI: 10.1016/j.cell.2018.07.016

Author: Ralph Turchiano

In short, I review clinical research on an almost daily basis. What I post tends to be articles that are relevant to the readers in addition to some curiosities that have intriguing potential. As a hobby, I truly enjoy the puzzle-solving play that statistics and programming as in the python language bring to the table. I just do not enjoy problem-solving, I love problem-solving and the childlike inspiration and exploration of that innocent exhilaration of discovering something new. Enjoy ;-)