Plant-based diet ramps up metabolism

Plant-based participants increased after-meal calorie burn by 18.7% after 16 weeks

The study randomly assigned participants–who were overweight and had no history of diabetes–to an intervention or control group in a 1:1 ratio. For 16 weeks, participants in the intervention group followed a low-fat, plant-based diet based on fruits, vegetables, whole grains, and legumes with no calorie limit. The control group made no diet changes. Neither group changed exercise or medication routines, unless directed by their personal doctors.

#plantdiet #metabolism #diet

Hana Kahleova et al, Effect of a Low-Fat Vegan Diet on Body Weight, Insulin Sensitivity, Postprandial Metabolism, and Intramyocellular and Hepatocellular Lipid Levels in Overweight Adults, JAMA Network Open (2020). DOI: 10.1001/jamanetworkopen.2020.25454

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2773291

https://www.pcrm.org/

Prebiotics may help activate anti-tumor immunity

Prebiotics may help activate anti-tumor immunity

Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that two prebiotics, mucin and inulin, slowed the growth of melanoma in mice by boosting the immune system’s ability to fight cancer. In contrast to probiotics, which are live bacterial strains, prebiotics are “food” for bacteria and stimulate the growth of diverse beneficial populations. The study, published today in Cell Reports, provides further evidence that gut microbes have a role in shaping the immune response to cancer, and supports efforts to target the gut microbiome to enhance the efficacy of cancer therapy.

#inulin #prebiotics #cancer

Prebiotic-Induced Anti-tumor Immunity Attenuates Tumor Growth

Yan Li, Lisa Elme´ n, Igor Segota, Tao Long, Scott N. Peterson, Ze’ev A. Ronai

https://doi.org/10.1016/j.celrep.2020.01.035

https://www.sciencedirect.com/science/article/pii/S2211124720300504#app2