Researchers identify melatonin as a possible COVID-19 treatment

Analysis of patient data from Cleveland Clinic’s COVID-19 registry also revealed that melatonin usage was associated with a nearly 30 percent reduced likelihood of testing positive for SARS-CoV-2 (the virus that causes COVID-19) after adjusting for age, race, smoking history and various disease comorbidities. Notably, the reduced likelihood of testing positive for the virus increased from 30 to 52 percent for African Americans when adjusted for the same variables

#melatonin #covid19 #sarscov2

Yadi Zhou, Yuan Hou, Jiayu Shen, Reena Mehra, Asha Kallianpur, Daniel A. Culver, Michaela U. Gack, Samar Farha, Joe Zein, Suzy Comhair, Claudio Fiocchi, Thaddeus Stappenbeck, Timothy Chan, Charis Eng, Jae U. Jung, Lara Jehi, Serpil Erzurum, Feixiong Cheng. A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19. PLOS Biology, 2020; 18 (11): e3000970 DOI: 10.1371/journal.pbio.3000970

The Powerful Blood Sugar Lowering Effect of Withania Coagulans

The Powerful Blood Sugar Lowering Effect of Withania Coagulans

Finally, diabetic mice that were fed the nanoparticles for 5 days showed about 40% lower blood glucose levels compared to their starting amounts. Surprisingly, even 5 days after the treatment ended, the mice showed a 60% reduction in blood glucose compared to their starting levels.

Kaarunya Sampathkumar, Siriporn Riyajan, Chiew Kei Tan, Philip Demokritou, Nuannoi Chudapongse, Say Chye Joachim Loo. Small-Intestine-Specific Delivery of Antidiabetic Extracts from Withania coagulans Using Polysaccharide-Based Enteric-Coated Nanoparticles. ACS Omega, 2019; 4 (7): 12049 DOI: 10.1021/acsomega.9b00823

Bad Breath quickly eliminated by a Ginger compound

Bad Breath quickly eliminated by a Ginger compound

Bad Breath quickly eliminated by a Ginger compound

As the results of this study show, the pungent principle of ginger, the so-called 6-gingerol, makes the level of the enzyme sulfhydryl oxidase 1 in saliva increase 16-fold within a few seconds. The saliva and breath analyses carried out on human volunteers show that the enzyme breaks down malodorous sulfur-containing compounds

Matthias Bader, Theresa Stolle, Maximilian Jennerwein, Jürgen Hauck, Buket Sahin, Thomas Hofmann. Chemosensate-Induced Modulation of the Salivary Proteome and Metabolome Alters the Sensory Perception of Salt Taste and Odor-Active Thiols. Journal of Agricultural and Food Chemistry, 2018; 66 (29): 7740 DOI: 10.1021/acs.jafc.8b02772