Randomized controlled trial
Results from many large clinical trials are never published
Contact: Tom Hughes tahughes@unch.unc.edu 919-966-6047 University of North Carolina Health Care Non-publication is more common among industry-funded trials, study finds CHAPEL HILL, N.C. – A new analysis of 585 large, randomized clinical trials registered with ClinicalTrials.gov finds that 29 percent… Read More ›
Unpublished trial data ‘violates an ethical obligation’ to study participants, say researchers / 1 in 3 large clinicals not Published
Contact: Stephanie Burns sburns@bmj.com 44-020-738-36920 BMJ-British Medical Journal Study finds almost 1 in 3 large clinical trials still not published 5 years after completion Almost one in three (29%) large clinical trials remain unpublished five years after completion. And… Read More ›
Probiotics found to reduce hepatic encephalopathy
Contact: Dimple Natali easlpressoffice@cohnwolfe.com 44-790-013-8904 European Association for the Study of the Liver Amsterdam, The Netherlands,Thursday 25 April 2013: Probiotics could emerge as a treatment plan to manage hepatic encephalopathy (HE) therapy after a new study announced at the International… Read More ›
TB infection rates set to ‘turn clock back to 1930s’
Contact: Stephanie Burns sburns@bmjgroup.com 44-020-738-36920 BMJ-British Medical Journal Special edition to mark World TB day maps new issues and approaches to curbing spread of infection During the 1930s, dedicated sanitaria and invasive surgery were commonly prescribed for those with the… Read More ›
Doubts cast on credibility of some published clinical trials: “a remarkable 93 percent of 2235 so-called RCTs published in some Chinese medical journals during 1994 to 2005 was flawed”
2009 study posted for filing Contact: Charlotte Webber charlotte.webber@biomedcentral.com 44-078-253-17342 BioMed Central This release is available in Chinese. Randomised Controlled Trials (RCTs) are considered the ‘gold standard’ research method for assessing new medical treatments. But research published in BioMed Central’s… Read More ›
Statins are unlikely to prevent blood clots
Press release from PLOS Medicine Despite previous studies suggesting the contrary, statins (cholesterol-lowering drugs) may not prevent blood clots (venous thrombo-embolism) in adults, according to a large analysis by international researchers published in this week’s PLOS Medicine. In 2009, an… Read More ›
‘Spin’ in media reports of scientific articles: 47% of articles contain ‘Spin”
Contact: Sumrina Yousufzai syousufzai@plos.org 415-568-3164 Public Library of Science Press releases and news stories reporting the results of randomized controlled trials often contain “spin”—specific reporting strategies (intentional or unintentional) emphasizing the beneficial effect of the experimental treatment—but such “spin” frequently… Read More ›
Relationship between statins and cognitive decline more complex than thought
INDIANAPOLIS – Previous explorations of a link between statins, a cholesterol lowering medication, and cognitive decline have produced inconsistent results. New research reveals that the relationship between statin use and cognitive decline appears even more complex than had… Read More ›
Engineering Evil 