Blueberry ameliorates hepatic fibrosis

2010 study posted for filing Contact: Ye-Ru Wang wjg@wjgnet.com 86-105-908-0039 World Journal of Gastroenterology Conventional drugs used in the treatment of liver diseases inevitably have side effects. An increasing number of natural substances have been studied to explore if they have protective effects on the liver. Blueberries have unique effects on human retinal, brain and…

Antifibrotic effects of green tea

2009 study posted for filing   Contact: Ye-Ru Wang wjg@wjgnet.com 86-105-908-0039 World Journal of Gastroenterology Several studies have shown that lipid peroxidation stimulates collagen production in fibroblasts and hepatic stellate cells (HSC), and plays an important role in the development of liver fibrosis. Hepatoprotective effects of green tea against carbon tetrachloride, cholestasis and alcohol induced…

Long-term treatment with Antacids can increase weight

Contact: Ye-Ru Wang wjg@wjgnet.com 86-105-908-0039 World Journal of Gastroenterology Long-term treatment with proton pump inhibitor can increase weight Gastroesophageal reflux disease (GERD) is the most common esophageal disorder, and frequently encountered in the primary care setting. Accumulating evidence has confirmed the excellent efficacy and safety of proton pump inhibitor (PPI) therapy in patients with all…

The popular insect repellent deet is neurotoxic: Urgent Action Needed

2009 Report posted for filing Contact: Graeme Baldwin graeme.baldwin@biomedcentral.com 44-203-192-2165 BioMed Central The active ingredient in many insect repellents, deet, has been found to be toxic to the central nervous system. Researchers writing in the open access journal BMC Biology say that more investigations are urgently needed to confirm or dismiss any potential neurotoxicity to…

Sedatives may increase suicide risk in older patients: 4 Fold Increase

2009 study posted for filing Contact: Graeme Baldwin graeme.baldwin@biomedcentral.com 44-203-192-2165 BioMed Central Sleeping tablets have been associated with a four-fold increase in suicide risk in the elderly. Researchers writing in the open access journal BMC Geriatrics have shown that, even after adjusting for the presence of psychiatric conditions, sedatives and hypnotics were both associated with…

Melatonin may be served as a potential anti-fibrotic drug

2009 study posted for filing Contact: Lai-Fu Li wjg@wjgnet.com 86-105-908-0039 World Journal of Gastroenterology In China, the incidence of liver cirrhosis is still high. Liver cirrhosis results from fibrosis. If treated properly at fibrosis stage, cirrhosis can be prevented. However, no effective antifibrosis drugs are available at present. Several lines of evidences suggest that oxidative…

Long-term L-carnitine supplementation prevents development of liver cancer

2009 study posted for filing Contact: Lin Tian wjg@wjgnet.com 86-105-908-0039 World Journal of Gastroenterology A study will be published on March 21, 2009 in World Journal of Gastroenterology addresses the question. A research group in King Saud University, Kingdom of Saudi Arabia investigated, for the first time, the role of carnitine, a naturally occurring compound…

Frankincense oil — a wise man’s remedy for bladder cancer

2009 study posted for filing Contact: Charlotte Webber charlotte.webber@biomedcentral.com 44-207-631-9980 BioMed Central Originating from Africa, India, and the Middle East, frankincense oil has been found to have many medicinal benefits. Now, an enriched extract of the Somalian Frankincense herb Boswellia carteri has been shown to kill off bladder cancer cells. Research presented in the open…

Scientific fraud: a sign of the times?

Are dodgy lab dealings a modern day dilemma or business as usual? The infamous Piltdown Man skull. Photograph: Rischgitz/Getty If you read about scientific fraud in the recent news, it would seem that there is much to worry about. It’s on the rise, apparently! There has been a 10-fold increase in the number of retracted…

How did glycine significantly decrease liver injury?:Protected both the lung and liver against lethal doses of endotoxins

2008 study posted for filing Contact: Lin-Lin Xiao wjg@wjgnet.com 86-105-908-0039 World Journal of Gastroenterology The nonessential amino acid glycine has been shown to be anti-inflammatory in several animal injury models. Recent studies demonstrated that dietary glycine protected both the lung and liver against lethal doses of endotoxin in rat or other animals and improved graft…

How does ellagic acid exert anti-cancer effect on pancreatic cancer cells?

Contact: Lai-Fu Li wjg@wjgnet.com 86-105-908-0039 World Journal of Gastroenterology Ellagic acid was previousely shown to have anticarcinogenic, antioxidant and antifibrosis properties. The anticarcinogenic effect of ellagic acid was shown in several types of cancers including skin, esophageal, and colon cancers. However the mechanisms mediating anti-cancer effect of ellagic acid, in general, remain unknown. A research…

Taurine has hepatoprotective effects, significantly protected injury form Liver Fibrosis

2008 study posted for filing Contact: Lin Tian wjg@wjgnet.com 86-105-908-0039 World Journal of Gastroenterology Can Taurine be a potent antioxidant drug in the future? Taurine is a potent antioxidant with hepatoprotective effects. Organelle based changes in hepatocytes after taurine treatment in experimental liver fibrosis were searched systematically and organelle injury scores decreased were found to…

Frankincense oil — a wise man’s remedy for bladder cancer

Contact: Charlotte Webber charlotte.webber@biomedcentral.com 44-207-631-9980 BioMed Central Originating from Africa, India, and the Middle East, frankincense oil has been found to have many medicinal benefits. Now, an enriched extract of the Somalian Frankincense herb Boswellia carteri has been shown to kill off bladder cancer cells. Research presented in the open access journal, BMC Complementary and…

What effect does melatonin have in colitis (IBD) ? ” bacterial translocation in postcolitis rats has been reversed by melatonin administration”

Contact: Jing Zhu wjg@wjgnet.com 0086-105-908-0039 World Journal of Gastroenterology In rats with experimental colitis, the marked increase in bacterial translocation in postcolitis rats has been reversed by melatonin administration. This is due to melatonin’s anti-inflammatory and anti-apoptotic effects. Using an elegant study design, including experimental colitis model, this research was performed by doctors from the…