Prebiotics may help activate anti-tumor immunity

Prebiotics may help activate anti-tumor immunity

Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that two prebiotics, mucin and inulin, slowed the growth of melanoma in mice by boosting the immune system’s ability to fight cancer. In contrast to probiotics, which are live bacterial strains, prebiotics are “food” for bacteria and stimulate the growth of diverse beneficial populations. The study, published today in Cell Reports, provides further evidence that gut microbes have a role in shaping the immune response to cancer, and supports efforts to target the gut microbiome to enhance the efficacy of cancer therapy.

#inulin #prebiotics #cancer

Prebiotic-Induced Anti-tumor Immunity Attenuates Tumor Growth

Yan Li, Lisa Elme´ n, Igor Segota, Tao Long, Scott N. Peterson, Ze’ev A. Ronai

https://doi.org/10.1016/j.celrep.2020.01.035

https://www.sciencedirect.com/science/article/pii/S2211124720300504#app2

Lifespan greatly enhanced with Synbiotics

Lifespan greatly enhanced with Synbiotics

Lifespan greatly enhanced with Synbiotics

Scientists fed fruit flies with a combination of probiotics and an herbal supplement called Triphala that was able to prolong the flies’ longevity by 60 % and protect them against chronic diseases associated with aging.

Susan Westfall, Nikita Lomis, Satya Prakash. Longevity extension in Drosophila through gut-brain communication. Scientific Reports, 2018; 8 (1) DOI: 10.1038/s41598-018-25382-z