Experiments using virulent avian flu strains pose risk of accidental release // PUBLIC RELEASE DATE: 20-May-2014 Research in mammals that aims to prevent future influenza pandemics raises ethical, public health concerns Boston, MA — Experiments creating dangerous flu strains that are transmissible between mammals pose too great a […]
Public release date: 7-Sep-2010 HRR-Re-Posted at Request – analyzed dozens of ghostwritten reviews and commentaries published in medical journals and journal supplements that were used to promote unproven benefits and downplay harms of Prempro – The analysis revealed that DesignWrite was paid US$25,000 to ghostwrite articles reporting clinical […]
Contact: Fiona Godwin medicinepress@plos.org Public Library of Science Recent changes to World Health Organization guidelines for starting anti-AIDS drugs (antiretroviral therapy—ART) in young children are unlikely to improve death rates but may increase the numbers of children receiving ART by simplifying access to treatment, according to a study […]
By Helen Briggs BBC News Depression is common across the world Depression is the second most common cause of disability worldwide after back pain, according to a review of research. The disease must be treated as a global public health priority, experts report in the journal PLOS […]
IQWiG: Reliable assessment of drugs is only possible on the basis of clinical study reports (CSRs) In 2012 researchers from the German Institute for Quality and Efficiency in Health Care (IQWiG) presented a study in the BMJ analysing information sources used in 16 health technology assessment (HTA) reports […]
A painkiller used by at least a million people in Britain a year should be banned because it raises the risk of heart attack and stroke by almost half, say British academics. Daily doses of painkillers can increase the risk of heart attacks and stroke Photo: ALAMY <!– remove […]
2008 study posted for filing Contact: Andrew Hyde press@plos.org 44-122-346-3330 Public Library of Science Over half of all supporting trials for FDA-approved drugs remained unpublished 5 years after approval, says new research published in this week’s PLoS Medicine. The most important trials determining efficacy, and those with statistically […]
Press release from PLOS Medicine Despite previous studies suggesting the contrary, statins (cholesterol-lowering drugs) may not prevent blood clots (venous thrombo-embolism) in adults, according to a large analysis by international researchers published in this week’s PLOS Medicine. In 2009, an additional analysis of data from a randomized controlled […]
Contact: Sumrina Yousufzai syousufzai@plos.org 415-568-3164 Public Library of Science Press releases and news stories reporting the results of randomized controlled trials often contain “spin”—specific reporting strategies (intentional or unintentional) emphasizing the beneficial effect of the experimental treatment—but such “spin” frequently comes from the abstract (summary) of the actual […]
Requested Repost Citation: Sismondo S (2007) Ghost management: How much of the medical literature is shaped behind the scenes by the pharmaceutical industry” PLoS Med 4(9): e286 Drug companies control or shape multiple steps in the research, analysis, writing, and publication of a large proportion of the […]
Contact: Sumrina Yousufzai syousufzai@plos.org 415-568-3164 Public Library of Science COI declarations and off-label drug use Conflict-of-interest statements made by physicians and scientists in their medical journal articles after they had been allegedly paid by pharmaceutical manufacturers as part of off-label marketing programs are often inadequate, highlighting the deficiencies […]
In an Essay that expands on a previous proposal to use the courts to prosecute those involved in ghostwriting on the basis of it being legal fraud, Xavier Bosch from the University of Barcelona, Spain and colleagues lay out three outline specific areas of legal liability in this […]
