Perelman School of Medicine

Metformin leads to an accumulation of AMP, which inhibits an enzyme called adenylate cyclase, thereby reducing levels of cyclic AMP and protein kinase activity: WOOPS

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Contact: Karen Kreeger karen.kreeger@uphs.upenn.edu 215-349-5658 University of Pennsylvania School of Medicine Most-used diabetes drug works in different way than previously thought Findings could lead to diabetes treatments with less side effects PHILADELPHIA – A team, led by senior author Morris… Read More ›