Herpes Virus Cleared from Cells BX795

Herpes Virus Cleared from Cells BX795

Herpes Virus Cleared from Cells BX795

From a completely accidental discovery: “BX795 is known as an inhibitor of TBK1, an enzyme involved in innate immunity and neuroinflammation. When TBK1 is suppressed in cells, infection is actually promoted. But when the researchers added higher concentrations of BX795 to cultured human corneal cells infected with HSV-1, the infection was quickly cleared.”

Citation: An off-target effect of BX795 blocks herpes simplex virus type 1 infection of the eye. Science Translational Medicine, 2018; 10 (428): eaan5861 DOI: 10.1126/scitranslmed.aan5861

Berry gives cancer therapy a boost

Berry gives cancer therapy a boost

Berry gives cancer therapy a boost
Researchers discover that blueberry when combined with radiation therapy increase it effectiveness from 20% to 70% in vitro. Quote:  “Radiation decreased cancer cells by approximately 20 percent. Interestingly, the cell group that received only blueberry extract had a 25 percent decrease in cancer. However, the biggest decline in cancer cells occurred in the radiation and extract group, with a decrease of about 70 percent.”

Citation: Blueberry as a Potential Radiosensitizer for Treating Cervical Cancer. Pathology & Oncology Research, 2017; DOI: 10.1007/s12253-017-0319-y