Cashew shell compound may mend damaged nerves

Cashew shell compound may mend damaged nerves

In laboratory experiments, a chemical compound found in the shell of the cashew nut promotes the repair of myelin, a team reports today.

#anacardicacid #nerverepair #cashews

Åsa Ljunggren-Rose, Chandramohan Natarajan, Pranathi Matta, Akansha Pandey, Isha Upender, and Subramaniam Sriram. Anacardic acid induces IL-33 and promotes remyelination in CNS. PNAS, 2020 DOI: 10.1073/pnas.2006566117

https://www.pnas.org/content/early/2020/08/11/2006566117

Testosterone eliminated MS symptoms – Animal model

Testosterone eliminated MS symptoms – Animal model

By accident researchers discovered that a guardian molecule cytokine IL-33 that was produced due to testosterone eliminated MS symptoms in mice.

Male-specific IL-33 expression regulates sex-dimorphic EAE susceptibility. Proceedings of the National Academy of Sciences, 2018; 201710401 DOI: 10.1073/pnas.1710401115