HSV-2 Herpes Topical Curcumin holds Promise

HSV-2 Herpes Topical Curcumin holds Promise

HSV-2 Herpes Topical Curcumin holds Promise

“Curcumin can stop the genital herpes virus, it helps in reducing the inflammation and makes it less susceptible to HIV and other STIs,” Prof Garg says.

#hsv2 #curcumin #herpes

Danielle Vitali, Puja Bagri, Jocelyn M. Wessels, Meenakshi Arora, Raghu Ganugula, Ankit Parikh, Talveer Mandur, Allison Felker, Sanjay Garg, M.N.V. Ravi Kumar, Charu Kaushic. Curcumin Can Decrease Tissue Inflammation and the Severity of HSV-2 Infection in the Female Reproductive Mucosa. International Journal of Molecular Sciences, 2020; 21 (1): 337 DOI: 10.3390/ijms21010337

https://www.mdpi.com/1422-0067/21/1/337

Herpes Virus Cleared from Cells BX795

Herpes Virus Cleared from Cells BX795

Herpes Virus Cleared from Cells BX795

From a completely accidental discovery: “BX795 is known as an inhibitor of TBK1, an enzyme involved in innate immunity and neuroinflammation. When TBK1 is suppressed in cells, infection is actually promoted. But when the researchers added higher concentrations of BX795 to cultured human corneal cells infected with HSV-1, the infection was quickly cleared.”

Citation: An off-target effect of BX795 blocks herpes simplex virus type 1 infection of the eye. Science Translational Medicine, 2018; 10 (428): eaan5861 DOI: 10.1126/scitranslmed.aan5861