Tag: Fred Hutchinson Cancer Research Center

Long-term tamoxifen use increases risk of an aggressive, hard to treat type of second breast cancer: 4 fold increase

2009 study posted for filing Contact: Kristen Woodward kwoodwar@fhcrc.org 206-667-5095 Fred Hutchinson Cancer Research Center Study finds a more than four-fold increased risk of ER negative second cancers SEATTLE – While long-term tamoxifen use among breast cancer survivors decreases their risk of developing the most common, less aggressive […]

Poxviruses defeat antiviral defenses by duplicating a gene – Engineered an E3L-deficient strain that was quickly able to increase infectious virus production by selectively increasing the number of copies of the K3L gene in its genome

Contact: Phil Sahm phil.sahm@hsc.utah.edu 801-581-2517 University of Utah Health Sciences Study helps explain how large DNA viruses undergo rapid evolution SALT LAKE CITY – Scientists have discovered that poxviruses, which are responsible for smallpox and other diseases, can adapt to defeat different host antiviral defenses by quickly and […]

Chemotherapy causes a 30 Fold Increase in WNT16B which drives more cancer and resistance (2nd Confirmation)

Public release date: 5-Aug-2012 [ Contact: Kristen Woodward kwoodwar@fhcrc.org 206-667-5095 Fred Hutchinson Cancer Research Center Researchers discover new mechanism behind resistance to cancer treatment Finding could lead to development of better therapies SEATTLE – Developing resistance to chemotherapy is a nearly universal, ultimately lethal consequence for cancer patients […]