Tag: Clinical trial

Dark Chocolate improves vision with 2 hours

Dark Chocolate improves vision with 2 hours   Contrast sensitivity and visual acuity were significantly higher 2 hours after consumption of a dark chocolate bar compared with a milk chocolate bar, but the duration of these effects and their influence in real-world performance await further testing. Rabin JC, […]

Results from many large clinical trials are never published

Contact: Tom Hughes tahughes@unch.unc.edu 919-966-6047 University of North Carolina Health Care Non-publication is more common among industry-funded trials, study finds CHAPEL HILL, N.C. – A new analysis of 585 large, randomized clinical trials registered with ClinicalTrials.gov finds that 29 percent have not been published in scientific journals. In […]

Unpublished trial data ‘violates an ethical obligation’ to study participants, say researchers / 1 in 3 large clinicals not Published

Contact: Stephanie Burns sburns@bmj.com 44-020-738-36920 BMJ-British Medical Journal   Study finds almost 1 in 3 large clinical trials still not published 5 years after completion Almost one in three (29%) large clinical trials remain unpublished five years after completion. And of these, 78% have no results publicly available, […]

Study shows how dietary supplement may block cancer cells

2010 study posted for filing   Contact: Darrell E. Ward Darrell.Ward@osumc.edu 614-293-3737 Ohio State University Medical Center COLUMBUS, Ohio – Researchers at the Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James) have discovered how a substance that is produced […]

Green tea extract appears to keep cancer in check in majority of CLL patients

2010 study posted for filing Contact: Karl Oestreich newsbureau@mayo.edu 507-284-5005 Mayo Clinic Mayo Clinic has conducted the first clinical studies of tea extract in cancer patients CHICAGO — ASCO Abstract Number: 6522 (http://abstract.asco.org/AbstView_74_47574.html). An extract of green tea appears to have clinical activity with low toxicity in chronic […]

BMJ editor urges Roche to fulfil promise to release Tamiflu trial data: Or anything that shows the drug does more good than harm.

Contact: Stephanie Burns sburns@bmjgroup.com 44-020-738-36920 BMJ-British Medical Journal BMJ editor urges Roche to fulfil promise to release Tamiflu trial data Journal launches open data campaign to compel greater accountability in healthcare In an open letter to company director, Professor Sir John Bell, she says: “Billions of pounds of […]

Doubts cast on credibility of some published clinical trials: “a remarkable 93 percent of 2235 so-called RCTs published in some Chinese medical journals during 1994 to 2005 was flawed”

2009 study posted for filing Contact: Charlotte Webber charlotte.webber@biomedcentral.com 44-078-253-17342 BioMed Central This release is available in Chinese. Randomised Controlled Trials (RCTs) are considered the ‘gold standard’ research method for assessing new medical treatments.  But research published in BioMed Central’s open access journal Trials shows that the design […]

Green tea extract shows promise in leukemia trials: Chronic lymphocytic leukemia 50 percent or greater decline in their lymph node size.

2009 study posted for filing ROCHESTER, Minn. — Mayo Clinic researchers are reporting positive results in early leukemia clinical trials using the chemical epigallocatechin gallate (EGCG), an active ingredient in green tea. The trial determined that patients with chronic lymphocytic leukemia (CLL) can tolerate the chemical fairly well […]

Cancer institute tackles sloppy data

Funder demands better evidence for biomarkers in clinical trials. Monya Baker 12 October 2012 Biologists combing through massive patient data sets often find potential biomarkers of certain diseases, but many of these signals turn out to be false. To weed out these useless associations, the US National Cancer […]

Questions of ethics and quality cloud globalization of clinical trials: Same drug in different populations could produce markedly different results

2009 study posted for filing Contact: Michelle Gailiun michelle.gailiun@duke.edu 919-724-5343 Duke University Medical Center DURHAM, N.C. – Top-tier U.S.-based pharmaceutical companies are moving their clinical trials overseas at warp speed, raising questions about ethics, quality control, and even the scientific value of their findings for people back in […]

Pneumococcal vaccine does not appear to protect against pneumonia: ” a systematic review and meta-analysis, looked at 22 clinical trials, reviews and meta-analyses and more than 100,000 participants “

2009 study posted for filing Contact: Kim Barnhardt kim.barnhardt@cmaj.ca 613-731-8610 x2224 Canadian Medical Association Journal Commonly used pneumococcal polysaccharide vaccines do not appear to be effective for preventing pneumonia, found a study by a team of researchers from Switzerland and the United Kingdom http://www.cmaj.ca/press/pg48.pdf. In many industrialized countries, […]


Contact: Jim Ritter Media Relations jritter@lumc.edu (708) 216-2445 Anne Dillon Director, Media Relations adillon@lumc.edu (708) 216-8232 More Sharing ServicesShare   MAYWOOD, Ill. – Loyola University Medical Center has launched the first clinical trial in the Midwest of an experimental melanoma treatment that genetically engineers a patient’s immune system […]

Melatonin may save eyesight in inflammatory disease: Uveitis

2008 study posted for filing Contact: Angela Colmone acolmone@asip.org 301-634-7953 American Journal of Pathology Buenos Aires, Argentina — Current research suggests that melatonin therapy may help treat uveitis, a common inflammatory eye disease. The related report by Sande et al., “Therapeutic Effect of Melatonin in Experimental Uveitis,” appears […]

Toxic drugs, toxic system: Sociologist predicts drug disasters “Drug disasters are literally built into the current system of drug testing and approvals in the United States,”

Repost 2008 Contact: Jackie Cooper jcooper@asanet.org 202-247-9871 American Sociological Association Study says harm from prescription drugs growing, cites fatal flaws in drug testing, approval and marketing BOSTON — Americans are likely to be exposed to unacceptable side effects of FDA-approved drugs such as Vioxx in the future because […]

Pain drug can kill resistant tuberculosis: Researchers claim may never be tested in TB clinical trials.

Public release date: 10-Sep-2012 [Print | E-mail| Share][ Close Window ] Contact: Lauren Woods law2014@med.cornell.edu 212-821-0560 New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College Researchers find low cost drug wipes out drug resistant TB, but worry it may not reach patients in need NEW YORK (September […]

St. Jude develops vaccine against potential pandemic influenza virus H5N1 using reverse genetics (Using H1N1, requested repost 2003)

Contact: Bonnie Cameron bonnie.cameron@stjude.org 901-495-4815 St. Jude Children’s Research Hospital Special modification of reverse genetics created at St. Jude allowed vaccine to be custom-made within weeks of emergence of virus (MEMPHIS, TENN.–April 2, 2003) Scientists at St. Jude Children’s Research Hospital announced today the development of a vaccine […]

Vitamin B3 reduces Alzheimer’s symptoms, lesions

Reposting Breakthroughs as current, to respark attention (From 2008) UC Irvine starts clinical trial on nicotinamide effect in Alzheimer’s patients Irvine, Calif. — An over-the-counter vitamin in high doses prevented memory loss in mice with Alzheimer’s disease, and UC Irvine scientists now are conducting a clinical trial to […]