We review the recent study ” Chondroitin sulfate as good as widely used anti-inflammatory for knee osteoarthritis “. With brief mention of the Glucosamine Sulfate trial showing superior long term results to acetaminophen. Citation: 1. Pharmaceutical-grade Chondroitin sulfate is as effective as celecoxib and superior to placebo in symptomatic knee osteoarthritis: the ChONdroitin versus CElecoxib versus Placebo Trial (CONCEPT). Annals of the Rheumatic Diseases, 2017; annrheumdis-2016-210860 DOI: 10.1136/annrheumdis-2016-210860 2. Glucosamine sulfate in the treatment of knee osteoarthritis symptoms: A randomized, double-blind, placebo-controlled study using acetaminophen as a side comparator DOI:10.1002/art.22371