Bisphenol A linked to chemotherapy resistance

2008 study posted for filing Contact: Dama Kimmon dama.kimmon@uc.edu 513-558-4519 University of Cincinnati CINCINNATI—Exposure to bisphenol A (BPA) may reduce the effectiveness of chemotherapy treatments, say University of Cincinnati (UC) scientists. The research study, led by UC’s Nira Ben-Jonathan, PhD, says that BPA—a man-made chemical found in a number of plastic products, including drinking bottles…

Solid tumor cells not killed by radiation and chemotherapy become stronger

2008 re-posted for filing Contact: Mary Jane Gore mary.gore@duke.edu 919-660-1309 Duke University Medical Center DURHAM, N.C. – Because of the way solid tumors adapt the body’s machinery to bring themselves more oxygen, chemotherapy and radiation may actually make these tumors stronger. “In a sense, these therapies can make the tumor healthier,” said Mark W. Dewhirst,…

Stem-cell-protecting drug could prevent the harmful side effects of radiation therapy: mTOR inhibitor rapamycin

Contact: Elisabeth Lyons elyons@cell.com 617-386-2121 Cell Press Radiation therapy is one of the most widely used cancer treatments, but it often damages normal tissue and can lead to debilitating conditions. A class of drugs known as mammalian target of rapamycin (mTOR) inhibitors can prevent radiation-induced tissue damage in mice by protecting normal stem cells that…

A compound extracted from olives inhibits cancer cells growth and prevents their appearance

Contact: José Antonio Lupiáñez Cara jlcara@ugr.es 34-958-240-069 University of Granada A research group of the University of Granadahas found out that maslinic acid, a compound present in the leaf and the olive skin wax extracted from alpeorujo (crushed olive pulp), has the capacity of preventing cancer as well as regulating apoptosis in carcinogenic processes. Maslinic…

Triphala and Its Active Constituent Chebulinic Acid Are Natural Inhibitors of Vascular Endothelial Growth Factor-A Mediated Angiogenesis

Triphala churna (THL) is a combination of three fruits that has been used for many years in India for the treatment of various diseases. There are now reports which indicate that THL can inhibit growth of malignant tumors in animals. However, the mechanisms by which THL mediates its anti-tumor actions are still being explored. Because…

Suppressive effects of a phytochemical cocktail on prostate cancer growth in vitro and in vivo. Abstract no. A104: 25% reduction in tumor size in 14 days

A commercially available nutrition drink reduces the growth of tumors in a mouse model of human prostate cancer by 25 percent in two weeks, according to researchers from the University of Sydney. The drink, Blueberry Punch, is a mixture of plant-based chemicals – phytochemicals – known to have anti-cancer properties. “While individual phytochemicals are successful…

Virus kills breast cancer cells in laboratory

A nondisease-causing virus kills human breast cancer cells in the laboratory, creating opportunities for potential new cancer therapies, according to Penn State College of Medicine researchers who tested the virus on three different breast cancer types that represent the multiple stages of breast cancer development. Adeno-associated virus type 2 (AAV2) is a virus that regularly…

Traditional herbal medicine kills pancreatic cancer cells, Jefferson researchers report (2nd Confirmation)

(PHILADELPHIA) An herb used in traditional medicine by many Middle Eastern countries may help in the fight against pancreatic cancer, one of the most difficult cancers to treat. Researchers at the Kimmel Cancer at Jefferson in Philadelphia have found that thymoquinone, an extract of nigella sativa seed oil, blocked pancreatic cancer cell growth and killed…

Chemotherapy causes a 30 Fold Increase in WNT16B which drives more cancer and resistance (2nd Confirmation)

Public release date: 5-Aug-2012 [ Contact: Kristen Woodward kwoodwar@fhcrc.org 206-667-5095 Fred Hutchinson Cancer Research Center Researchers discover new mechanism behind resistance to cancer treatment Finding could lead to development of better therapies SEATTLE – Developing resistance to chemotherapy is a nearly universal, ultimately lethal consequence for cancer patients with solid tumors – such as those…

Chemotherapy can backfire and boost cancer growth: study

Source: AFP 5AUG2012 Cancer-busting chemotherapy can cause damage to healthy cells which triggers them to secrete a protein that sustains tumour growth and resistance to further treatment, a study said Sunday. Researchers in the United States made the “completely unexpected” finding while seeking to explain why cancer cells are so resilient inside the human body…